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The map label for this gene is fbp

Identifier: 83311760

GI number: 83311760

Start: 2853154

End: 2854170

Strand: Reverse

Name: fbp

Synonym: amb2661

Alternate gene names: 83311760

Gene position: 2854170-2853154 (Counterclockwise)

Preceding gene: 83311764

Following gene: 83311758

Centisome position: 57.46

GC content: 63.42

Gene sequence:

>1017_bases
ATGCCGTACAAAAGGATCACGCTGACCCACTTCCTGTTGCAGGAACAGCGCCGCCTGGGCGGGTCGGGTTCGTTCACCGC
GCTGATGACCGACATCATCTTCGCCTGCAAGATGATCTCGCACGAGGTCAACCGCGGTGCGCTGGCCGGCAATCTGGGCG
TGGCGGGGTCGGAGAACGTCCAGGGCGAGGAGCAGAAGAAGCTCGACGTGCTGGCCAACGACATCTTCCTGCACATGAAC
GCCCTGGGCGGGTCCTATGCCGGCATGGCCTCGGAAGAGCTGGAAGACGTGCACGCCGTGCACGGCGCCGCCGATGGCAA
GTACCTGCTGCTGTTCGATCCGCTGGATGGCTCGTCCAACATCGACGTCAACATCTCGGTGGGGTCCATCTTCTCCATCC
TGAAGCTGCCCGAGGGTGCCAATGCCGGGTCCAAGGACGCCTTCCTGCAGCCCGGCGTGAAGCAGGTTGCCGCCGGCTAT
GCCCTTTACGGCTCGTCGACCATGCTGGTGCTGACCACCGGCAACGGGGTCAACGGCTTCACCCTCGACAACAACGTGGG
CATGTTCCTGCTGACCCACCCCAACATGACCATTCCGGCCGATACCAAGGAATTCGCCATCAACGCGTCCCGCGAGCGGT
TCTGGGAGCCGCCGGTGAAGCGCTATATCGATGAATGCCGCCAGGGCAAGGAAGGCCCCCGGGGTAAGGATTTCAACATG
CGCTGGGTGGCTTCCATGGTGGCCGAGGTGCATCGCATCCTGTGTCGCGGCGGCGTGTTCCTCTACCCGGCCGATACCGA
GAACATGAAGAAGGGCGGCAAGCTGCGCCTGATGTACGAAGCCAATCCCATGGCCTTCATCGTCGAGCAGGCGGGTGGTG
CCGCCACCACCGGCCGTGGTCGCATGATGGAGGTTCCTCCCACCGGCCTGCATCAGCGCGTGCCGGTGATCCTGGGCTCC
AAGGAAGAGGTGGAGCGCATCGGCGCCTACCACGCCGAATACGACGCGAAGAAGTAA

Upstream 100 bases:

>100_bases
AAGTCCCCACCTTCACATTGCATTTTTGTGGCCTTAAGCTTAAGTCTTGGCGCCACCCAACGACGGGGAAAATCCCGCCT
TAAGCCTCGAGAGGGAAGAC

Downstream 100 bases:

>100_bases
TACCAGCCTGCGCTGAGTGAAACTCATCGCGGGTTGGTTAGGCCCAAGGGGCCGCGCGCCTTACGCGCGGGAGGCAAGGG
CGCACGGCGCCCGCCCGCCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPYKRITLTHFLLQEQRRLGGSGSFTALMTDIIFACKMISHEVNRGALAGNLGVAGSENVQGEEQKKLDVLANDIFLHMN
ALGGSYAGMASEELEDVHAVHGAADGKYLLLFDPLDGSSNIDVNISVGSIFSILKLPEGANAGSKDAFLQPGVKQVAAGY
ALYGSSTMLVLTTGNGVNGFTLDNNVGMFLLTHPNMTIPADTKEFAINASRERFWEPPVKRYIDECRQGKEGPRGKDFNM
RWVASMVAEVHRILCRGGVFLYPADTENMKKGGKLRLMYEANPMAFIVEQAGGAATTGRGRMMEVPPTGLHQRVPVILGS
KEEVERIGAYHAEYDAKK

Sequences:

>Translated_338_residues
MPYKRITLTHFLLQEQRRLGGSGSFTALMTDIIFACKMISHEVNRGALAGNLGVAGSENVQGEEQKKLDVLANDIFLHMN
ALGGSYAGMASEELEDVHAVHGAADGKYLLLFDPLDGSSNIDVNISVGSIFSILKLPEGANAGSKDAFLQPGVKQVAAGY
ALYGSSTMLVLTTGNGVNGFTLDNNVGMFLLTHPNMTIPADTKEFAINASRERFWEPPVKRYIDECRQGKEGPRGKDFNM
RWVASMVAEVHRILCRGGVFLYPADTENMKKGGKLRLMYEANPMAFIVEQAGGAATTGRGRMMEVPPTGLHQRVPVILGS
KEEVERIGAYHAEYDAKK
>Mature_337_residues
PYKRITLTHFLLQEQRRLGGSGSFTALMTDIIFACKMISHEVNRGALAGNLGVAGSENVQGEEQKKLDVLANDIFLHMNA
LGGSYAGMASEELEDVHAVHGAADGKYLLLFDPLDGSSNIDVNISVGSIFSILKLPEGANAGSKDAFLQPGVKQVAAGYA
LYGSSTMLVLTTGNGVNGFTLDNNVGMFLLTHPNMTIPADTKEFAINASRERFWEPPVKRYIDECRQGKEGPRGKDFNMR
WVASMVAEVHRILCRGGVFLYPADTENMKKGGKLRLMYEANPMAFIVEQAGGAATTGRGRMMEVPPTGLHQRVPVILGSK
EEVERIGAYHAEYDAKK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=322, Percent_Identity=47.5155279503106, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI16579888, Length=322, Percent_Identity=47.5155279503106, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI22907028, Length=321, Percent_Identity=43.3021806853583, Blast_Score=255, Evalue=4e-68,
Organism=Escherichia coli, GI1790679, Length=331, Percent_Identity=43.202416918429, Blast_Score=265, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17508131, Length=333, Percent_Identity=48.048048048048, Blast_Score=300, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6323409, Length=325, Percent_Identity=42.4615384615385, Blast_Score=265, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45550998, Length=328, Percent_Identity=46.6463414634146, Blast_Score=263, Evalue=9e-71,
Organism=Drosophila melanogaster, GI19921562, Length=326, Percent_Identity=46.0122699386503, Blast_Score=263, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_MAGSA (Q2W3W0)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422024.1
- HSSP:   P09467
- ProteinModelPortal:   Q2W3W0
- SMR:   Q2W3W0
- STRING:   Q2W3W0
- GeneID:   3802932
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2661
- NMPDR:   fig|342108.5.peg.2358
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- PhylomeDB:   Q2W3W0
- BioCyc:   MMAG342108:AMB2661-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36744; Mature: 36612

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00124 FBPASE

Important sites: BINDING 208-208 BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYKRITLTHFLLQEQRRLGGSGSFTALMTDIIFACKMISHEVNRGALAGNLGVAGSENV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
QGEEQKKLDVLANDIFLHMNALGGSYAGMASEELEDVHAVHGAADGKYLLLFDPLDGSSN
CCCHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
IDVNISVGSIFSILKLPEGANAGSKDAFLQPGVKQVAAGYALYGSSTMLVLTTGNGVNGF
EEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEECCCEEEEEEECCCCCCE
TLDNNVGMFLLTHPNMTIPADTKEFAINASRERFWEPPVKRYIDECRQGKEGPRGKDFNM
EECCCCCEEEEECCCEECCCCCHHHEEECCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCH
RWVASMVAEVHRILCRGGVFLYPADTENMKKGGKLRLMYEANPMAFIVEQAGGAATTGRG
HHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCEEEEEECCCEEEEEECCCCCEECCCC
RMMEVPPTGLHQRVPVILGSKEEVERIGAYHAEYDAKK
EEEECCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PYKRITLTHFLLQEQRRLGGSGSFTALMTDIIFACKMISHEVNRGALAGNLGVAGSENV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
QGEEQKKLDVLANDIFLHMNALGGSYAGMASEELEDVHAVHGAADGKYLLLFDPLDGSSN
CCCHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
IDVNISVGSIFSILKLPEGANAGSKDAFLQPGVKQVAAGYALYGSSTMLVLTTGNGVNGF
EEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCEEEECCCEEEEEEECCCCCCE
TLDNNVGMFLLTHPNMTIPADTKEFAINASRERFWEPPVKRYIDECRQGKEGPRGKDFNM
EECCCCCEEEEECCCEECCCCCHHHEEECCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCH
RWVASMVAEVHRILCRGGVFLYPADTENMKKGGKLRLMYEANPMAFIVEQAGGAATTGRG
HHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCEEEEEECCCEEEEEECCCCCEECCCC
RMMEVPPTGLHQRVPVILGSKEEVERIGAYHAEYDAKK
EEEECCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA