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The map label for this gene is yjjN [C]

Identifier: 83311243

GI number: 83311243

Start: 2320501

End: 2321631

Strand: Reverse

Name: yjjN [C]

Synonym: amb2144

Alternate gene names: 83311243

Gene position: 2321631-2320501 (Counterclockwise)

Preceding gene: 83311248

Following gene: 83311242

Centisome position: 46.74

GC content: 66.93

Gene sequence:

>1131_bases
ATGGCGCGACGGTGCCGCGGGTCGGAGATAACGGGAAGAGAGAGGGAATACGGAATGAGCATTTCCGCTTATCGTTGGAT
GATGACCGGTGTCGGCCAGCCCATGGTGAAGGAAGCCATGGAAATCGCCGCGCCGGGCGCCGGTGAGGTGCTGGTCGAGG
TCGCGGGCTGCGGCGTCTGCCACACGGATCTGGACTACTATTACAACGGCGTGCGCACCAACCACGCCCTGCCCCTGGCG
CTTGGCCACGAGATCAGCGGCCGGGTGATTCAGGCCGGCGCCGGCGCCGAAAGCTGGGTCGGCAAGGCCGTCATCATTTC
GGCGGTGATTCCCTGCGGCCAGTGCGACCTGTGCAAGCGCGGCAAGGGCACCATCTGCCGCTCGCAGAAGATGCCGGGCA
ACGATCTGCAGGGCGGCTTCGCCACCCATATCACCGTCCCCGCCAACGGGCTGTGCGCCGTGGACGAGGCCCGGCTGAAG
GCTGCCGGCCTGGAGCTGTCCGAGGTCTCCGTGGTGGCCGACGCGCTGACCACCCCCTATCAGGCCGCCGTGCAGGCCGG
CATCGGCCAGGGCGACCTGGTGATCGTCATCGGCTGTGGCGGCGTGGGCGGCTATTCCGTCCAGGTGGCCTCGGCCATGG
GCGCCACCGTGGTGGCTCTGGACATCGACCCGGTCAAGCTGGAAGCGGTCAAGGCGGCGGGCGCCAAGCTGACGCTGAAC
CCCAAGGACTTCCCCTCGACCCGCGAGATCAAGAAGGAAATCGGCGCCTTCGCCAAGGCCCAGGGCCTGCGCTCCACCGA
GTGGATCATCATGGAATGCTCGGGCAGCGTTCCCGGCCAGCAGAGCGCCTTCGACCTGATGGTCCATGGCTGCACCATCT
GCGTGGTGGGCTACACCATGAACAAGGCCGAGTTCCGCCTGTCCAACCTGATGGCCTTCCATGCCCGCGCGCTGGGCAAT
TGGGGCTGCCCGCCGGACCTGTATCCCGGCGCCCTGGATCTGGTCCTGTCGGGCAAGATCAACGTGAAGAACTTCGTCGA
GCGTCGCCCGCTGGACAGCATCAACGACACGTTCGCCGCCGTGCACGACCACAAGCTGTCGCGCCGCGCCGTCCTGTGCC
CCAACGCCTAA

Upstream 100 bases:

>100_bases
TGCATACCACCCATTTGGGTCGGACGACAAGCCCACAAGCTGCACTTGACGGCTAATTCGGTATTGTGGTACGCATTTAC
GGAATAATACAGGGCGATCC

Downstream 100 bases:

>100_bases
AAGAAATTCAAGAGAGGGAGAGTCCTGGTCATGAAGAAGGAAACCGCGGCCATCGTCGATTCAACGGCGCCCGCCCACCT
CAACGATCACAATCTGGTCC

Product: Zn-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MARRCRGSEITGREREYGMSISAYRWMMTGVGQPMVKEAMEIAAPGAGEVLVEVAGCGVCHTDLDYYYNGVRTNHALPLA
LGHEISGRVIQAGAGAESWVGKAVIISAVIPCGQCDLCKRGKGTICRSQKMPGNDLQGGFATHITVPANGLCAVDEARLK
AAGLELSEVSVVADALTTPYQAAVQAGIGQGDLVIVIGCGGVGGYSVQVASAMGATVVALDIDPVKLEAVKAAGAKLTLN
PKDFPSTREIKKEIGAFAKAQGLRSTEWIIMECSGSVPGQQSAFDLMVHGCTICVVGYTMNKAEFRLSNLMAFHARALGN
WGCPPDLYPGALDLVLSGKINVKNFVERRPLDSINDTFAAVHDHKLSRRAVLCPNA

Sequences:

>Translated_376_residues
MARRCRGSEITGREREYGMSISAYRWMMTGVGQPMVKEAMEIAAPGAGEVLVEVAGCGVCHTDLDYYYNGVRTNHALPLA
LGHEISGRVIQAGAGAESWVGKAVIISAVIPCGQCDLCKRGKGTICRSQKMPGNDLQGGFATHITVPANGLCAVDEARLK
AAGLELSEVSVVADALTTPYQAAVQAGIGQGDLVIVIGCGGVGGYSVQVASAMGATVVALDIDPVKLEAVKAAGAKLTLN
PKDFPSTREIKKEIGAFAKAQGLRSTEWIIMECSGSVPGQQSAFDLMVHGCTICVVGYTMNKAEFRLSNLMAFHARALGN
WGCPPDLYPGALDLVLSGKINVKNFVERRPLDSINDTFAAVHDHKLSRRAVLCPNA
>Mature_375_residues
ARRCRGSEITGREREYGMSISAYRWMMTGVGQPMVKEAMEIAAPGAGEVLVEVAGCGVCHTDLDYYYNGVRTNHALPLAL
GHEISGRVIQAGAGAESWVGKAVIISAVIPCGQCDLCKRGKGTICRSQKMPGNDLQGGFATHITVPANGLCAVDEARLKA
AGLELSEVSVVADALTTPYQAAVQAGIGQGDLVIVIGCGGVGGYSVQVASAMGATVVALDIDPVKLEAVKAAGAKLTLNP
KDFPSTREIKKEIGAFAKAQGLRSTEWIIMECSGSVPGQQSAFDLMVHGCTICVVGYTMNKAEFRLSNLMAFHARALGNW
GCPPDLYPGALDLVLSGKINVKNFVERRPLDSINDTFAAVHDHKLSRRAVLCPNA

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565154, Length=365, Percent_Identity=27.1232876712329, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI34577061, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4501929, Length=247, Percent_Identity=29.5546558704453, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501933, Length=258, Percent_Identity=27.906976744186, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI262073058, Length=239, Percent_Identity=27.6150627615063, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI71743840, Length=239, Percent_Identity=27.6150627615063, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI156523966, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4501939, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI226510992, Length=326, Percent_Identity=25.7668711656442, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786552, Length=368, Percent_Identity=27.445652173913, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787863, Length=334, Percent_Identity=27.2455089820359, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788075, Length=353, Percent_Identity=25.4957507082153, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788407, Length=215, Percent_Identity=30.6976744186047, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790718, Length=201, Percent_Identity=30.3482587064677, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082125, Length=292, Percent_Identity=24.6575342465753, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081918, Length=329, Percent_Identity=27.6595744680851, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788073, Length=327, Percent_Identity=23.8532110091743, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790045, Length=259, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786518, Length=230, Percent_Identity=32.6086956521739, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082401, Length=328, Percent_Identity=25.3048780487805, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=348, Percent_Identity=25.8620689655172, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=373, Percent_Identity=26.8096514745308, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71997431, Length=375, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=276, Percent_Identity=26.8115942028986, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=346, Percent_Identity=24.5664739884393, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=305, Percent_Identity=27.8688524590164, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=218, Percent_Identity=30.2752293577982, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=305, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=26.3013698630137, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=334, Percent_Identity=26.9461077844311, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=363, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=224, Percent_Identity=30.3571428571429, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=222, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737895, Length=370, Percent_Identity=26.7567567567568, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737897, Length=302, Percent_Identity=27.8145695364238, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137530, Length=318, Percent_Identity=27.0440251572327, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550770, Length=332, Percent_Identity=25.6024096385542, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551930, Length=332, Percent_Identity=25.6024096385542, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221457811, Length=332, Percent_Identity=25.6024096385542, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39636; Mature: 39505

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRCRGSEITGREREYGMSISAYRWMMTGVGQPMVKEAMEIAAPGAGEVLVEVAGCGVC
CCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCEE
HTDLDYYYNGVRTNHALPLALGHEISGRVIQAGAGAESWVGKAVIISAVIPCGQCDLCKR
ECCHHHHHCCEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHEEEEHHCCCCCCCHHHC
GKGTICRSQKMPGNDLQGGFATHITVPANGLCAVDEARLKAAGLELSEVSVVADALTTPY
CCCCEEECCCCCCCCCCCCEEEEEEECCCCEEECHHHHHHHCCCCHHHHHHHHHHHCCCH
QAAVQAGIGQGDLVIVIGCGGVGGYSVQVASAMGATVVALDIDPVKLEAVKAAGAKLTLN
HHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCCEEEEEECCCCCEEEEC
PKDFPSTREIKKEIGAFAKAQGLRSTEWIIMECSGSVPGQQSAFDLMVHGCTICVVGYTM
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCEEEEEEEEEC
NKAEFRLSNLMAFHARALGNWGCPPDLYPGALDLVLSGKINVKNFVERRPLDSINDTFAA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHH
VHDHKLSRRAVLCPNA
HHHCCCCCCEEECCCC
>Mature Secondary Structure 
ARRCRGSEITGREREYGMSISAYRWMMTGVGQPMVKEAMEIAAPGAGEVLVEVAGCGVC
CCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCEE
HTDLDYYYNGVRTNHALPLALGHEISGRVIQAGAGAESWVGKAVIISAVIPCGQCDLCKR
ECCHHHHHCCEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHEEEEHHCCCCCCCHHHC
GKGTICRSQKMPGNDLQGGFATHITVPANGLCAVDEARLKAAGLELSEVSVVADALTTPY
CCCCEEECCCCCCCCCCCCEEEEEEECCCCEEECHHHHHHHCCCCHHHHHHHHHHHCCCH
QAAVQAGIGQGDLVIVIGCGGVGGYSVQVASAMGATVVALDIDPVKLEAVKAAGAKLTLN
HHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCCEEEEEECCCCCEEEEC
PKDFPSTREIKKEIGAFAKAQGLRSTEWIIMECSGSVPGQQSAFDLMVHGCTICVVGYTM
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHCCEEEEEEEEEC
NKAEFRLSNLMAFHARALGNWGCPPDLYPGALDLVLSGKINVKNFVERRPLDSINDTFAA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHH
VHDHKLSRRAVLCPNA
HHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]