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The map label for this gene is hpcD [H]

Identifier: 83309902

GI number: 83309902

Start: 860917

End: 861384

Strand: Reverse

Name: hpcD [H]

Synonym: amb0803

Alternate gene names: 83309902

Gene position: 861384-860917 (Counterclockwise)

Preceding gene: 83309903

Following gene: 83309901

Centisome position: 17.34

GC content: 60.9

Gene sequence:

>468_bases
TTGGACACGCCGTTCCAGGACGAGATCCCTCCTCCCGCAGGTCGTCGGGATGACATTCAAATTTGCGCGAGGAGACACAT
GCCCCACTTCATCGCCGAGTACACCGACAACATCAAGGACCGGGCCGACATCCGGGGAATGCTGAAGAAGGTCAACCAGG
TGCTGATCGCCCAGGGCGGCGTTTTCCCCATCGGCGGCATCCGCGCCCGCGCCATCGAGTTGCACGACTATGTGATGGCC
GACGACGAGGAGGATTACGGCTTCGTCCACTGCACGCTCAAGATCGGCGCCGGACGCAGCGACGCCGAGAAGAAGAAGGC
CTGCGAGGAGCTGTTCGCCATGATGACGGACCACTTCGCCCCTCTTTACGACAGCGGCTATTTCGCGCTCTCCATGGAGC
TCTACGAGTTCGACGAGGGCGGCACCTTCAAGAAGAACAACGTCCACGCCCGTTTCAGGAAGGCTTGA

Upstream 100 bases:

>100_bases
CCGGCCAGGTCAACGCGGTCTTCCCCGTCGCCGCCTGATTTGCACAACCTGTCATCCCGAGCGCCGGCGAGGGATCTCCG
CCTGGAACGGTGAAGCCAAC

Downstream 100 bases:

>100_bases
CCCATGGCTCTCACGCTCGATCAGATCAATGCCGCCGCCGCCCGCCTGCATCGGGCCGAGCAGACCCGACACCAGTGCGG
CCAGATTTCGCTGGACCACC

Product: 5-carboxymethyl-2-hydroxymuconate isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MDTPFQDEIPPPAGRRDDIQICARRHMPHFIAEYTDNIKDRADIRGMLKKVNQVLIAQGGVFPIGGIRARAIELHDYVMA
DDEEDYGFVHCTLKIGAGRSDAEKKKACEELFAMMTDHFAPLYDSGYFALSMELYEFDEGGTFKKNNVHARFRKA

Sequences:

>Translated_155_residues
MDTPFQDEIPPPAGRRDDIQICARRHMPHFIAEYTDNIKDRADIRGMLKKVNQVLIAQGGVFPIGGIRARAIELHDYVMA
DDEEDYGFVHCTLKIGAGRSDAEKKKACEELFAMMTDHFAPLYDSGYFALSMELYEFDEGGTFKKNNVHARFRKA
>Mature_155_residues
MDTPFQDEIPPPAGRRDDIQICARRHMPHFIAEYTDNIKDRADIRGMLKKVNQVLIAQGGVFPIGGIRARAIELHDYVMA
DDEEDYGFVHCTLKIGAGRSDAEKKKACEELFAMMTDHFAPLYDSGYFALSMELYEFDEGGTFKKNNVHARFRKA

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 17648; Mature: 17648

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPFQDEIPPPAGRRDDIQICARRHMPHFIAEYTDNIKDRADIRGMLKKVNQVLIAQGG
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
VFPIGGIRARAIELHDYVMADDEEDYGFVHCTLKIGAGRSDAEKKKACEELFAMMTDHFA
CCCCCCCEEEEEEEEHEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
PLYDSGYFALSMELYEFDEGGTFKKNNVHARFRKA
CCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MDTPFQDEIPPPAGRRDDIQICARRHMPHFIAEYTDNIKDRADIRGMLKKVNQVLIAQGG
CCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
VFPIGGIRARAIELHDYVMADDEEDYGFVHCTLKIGAGRSDAEKKKACEELFAMMTDHFA
CCCCCCCEEEEEEEEHEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
PLYDSGYFALSMELYEFDEGGTFKKNNVHARFRKA
CCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]