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The map label for this gene is ftsK [H]

Identifier: 82750877

GI number: 82750877

Start: 1235726

End: 1238095

Strand: Direct

Name: ftsK [H]

Synonym: SAB1138

Alternate gene names: 82750877

Gene position: 1235726-1238095 (Clockwise)

Preceding gene: 82750876

Following gene: 82750878

Centisome position: 45.06

GC content: 33.76

Gene sequence:

>2370_bases
TTGGCACAAGCAAAAAAGAAATCGACAGCTAAGAAAAAAACAACATCAAAAAAAAGAACAAATTCGAGGAAAAAGAAGAA
TGATAATCCGATACGTTATGTCATAGCTATTTTAGTAGTTGTATTAATGGTGTTGGGTGTTTTCCAATTAGGAATAATAG
GTCGTCTAATTGACAGCTTCTTTAATTATTTATTTGGGTACAGTAGATATTTAACATATATTTTAGTACTCTTAGCAACT
GGTTTTATTACATACTCTAAACGTATTCCTAAAACTAGACGAACGGCTGGTTCGATTGTATTGCAAATTGCATTGCTATT
TGTATCACAGTTAGTTTTTCATTTTAATAGTGGTATCAAAGCTGAAAGAGAACCTGTACTTTCTCATGTGTATCAGTCAT
ACCAACACAGTCATTTTCCAAATTTTGGTGGCGGTGTATTAGGCTTTTATTTATTAGAGTTAAGCGTACCTTTAATTTCA
TTATTTGGTGTATGTATTATTACTATTTTATTATTATGCTCAAGTGTTATTTTATTAACAAACCATCAACATCGTGATGT
TGCAAAAGTTGCACTGGAAAATATAAAAGCTTGGTTTGGTTCATTTAATGAAAAAATGTCGGAAAGAAACCAAGAAAAAC
AATTGAAGCGTGAAGAAAAAGCGAGACTTAAAGAAGAACAAAAGGCACGTCAAAATGAACAGCCACAAATAAAAGATGTG
AGTGATTTTACGGAAGTGCCTCAAGAAAGAGATATTCCAATTTATGGGCATACTGAAAATGAAAGTAAAAGCCAGAGTCA
ACCAAGTCGAAAAAAGCGAGTGTTTGATGCAGAGAATAGTTCGAATAACATCGTAAATCATAATCAAGCAGATCAGCAAG
AGCAATTAACAGAACAAACTCATAACAGTGTTGAAAGTGAAAACACTATTGAAGAAGCTGGTGAAGTTACGAATGTATCG
TATGTTGTTCCACCGTTAACTTTACTTAATCAACCTGCAAAACAAAAAGCAACATCTAAAGCTGAAGTACAACGTAAAGG
ACAAGTACTAGAGAATACATTAAAAGATTTTGGGGTAAATGCAAAAGTGACACAAATTAAAATTGGTCCTGCAGTAACTC
AATATGAAATTCAACCAGCTCAAGGGGTTAAAGTGAGTAAAATTGTAAACTTGCATAATGATATTGCATTAGCTTTAGCA
GCAAAAGATGTTAGAATCGAAGCGCCAATACCTGGTCGCTCTGCAGTAGGTATTGAAGTGCCAAATGAGAAAATTTCATT
AGTTTCACTAAAAGAAGTTTTAGATGAAAAATTCCCGTCTAATAATAAACTAGAAGTTGGATTAGGAAGAGATATATCAG
GTGATCCAATTACTGTTCCACTAAATGAAATGCCACACTTATTGGTGGCAGGATCGACGGGTAGTGGTAAATCTGTTTGT
ATAAATGGTATTATTACAAGTATTTTATTAAATGCTAAGCCGCATGAAGTTAAACTTATGTTAATCGATCCGAAAATGGT
TGAACTAAATGTTTATAACGGAATTCCACATTTATTAATTCCGGTTGTTACAAATCCTCATAAAGCTGCTCAAGCTTTAG
AAAAAATTGTAGCTGAGATGGAAAGACGTTATGATTTATTCCAACATTCATCAACTAGAAATATTAAAGGTTATAACGAA
TTAATCCGTAAGCAAAATCAAGAATTAGATGAGAAGCAACCAGAATTACCTTATATCGTTGTTATTGTAGATGAGCTTGC
AGATTTAATGATGGTAGCTGGTAAAGAAGTTGAAAATGCGATTCAACGTATCACACAAATGGCACGTGCAGCAGGTATAC
ATTTGATTGTAGCGACACAAAGACCTTCTGTGGATGTAATTACAGGTATCATTAAAAATAATATTCCATCTAGAATTGCT
TTTGCTGTGAGTTCTCAAACAGATTCAAGAACTATTATTGGTACTGGCGGCGCAGAAAAGTTACTTGGTAAAGGTGACAT
GTTATACGTTGGAAATGGTGACTCATCACAAACACGTATTCAAGGGGCGTTTTTAAGTGACCAAGAGGTGCAAGATGTTG
TAAATTATGTAGTAGAACAACAACAGGCAAATTATGTAAAAGAAATGGAACCAGATGCACCAGTGGATAAATCGGAAATG
AAAAGTGAAGATGCTTTATATGATGAAGCGTATTTGTTTGTTGTTGAACAACAAAAGGCAAGTACATCATTGTTACAACG
CCAATTTAGAATTGGTTATAATAGAGCATCTAGGTTGATGGATGATTTAGAACGCAATCAGGTAATCGGTCCACAAAAAG
GAAGCAAGCCTAGACAAGTTTTAATAGATCTTAATAATGACGAGGTGTAA

Upstream 100 bases:

>100_bases
CTCTTTCATCGTCTGTTTGGACTACATATTCTAAACATCAAATAGGAAATAATATATAATAACGTCGTTTTAACTAAGGT
AACATAAGGAGGTGCGTCAA

Downstream 100 bases:

>100_bases
AAAAATGTCAGAAATGAATGCGGTATATAACGTTAAACAATACATTTTAAATTTGATTAAGCAAAATAAATTGGAATATG
GTGACCAACTTCCAAGTAAT

Product: SpoIII family DNA translocase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 788

Protein sequence:

>789_residues
MAQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLAT
GFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSHVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
LFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
SDFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFDAENSSNNIVNHNQADQQEQLTEQTHNSVESENTIEEAGEVTNVS
YVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALA
AKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVC
INGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNE
LIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIA
FAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEM
KSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV

Sequences:

>Translated_789_residues
MAQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLAT
GFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSHVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
LFGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
SDFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFDAENSSNNIVNHNQADQQEQLTEQTHNSVESENTIEEAGEVTNVS
YVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALA
AKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVC
INGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNE
LIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIA
FAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEM
KSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV
>Mature_788_residues
AQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATG
FITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSHVYQSYQHSHFPNFGGGVLGFYLLELSVPLISL
FGVCIITILLLCSSVILLTNHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDVS
DFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFDAENSSNNIVNHNQADQQEQLTEQTHNSVESENTIEEAGEVTNVSY
VVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAA
KDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCI
NGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNEL
IRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAF
AVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMK
SEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=484, Percent_Identity=46.900826446281, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88111; Mature: 87980

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEECCCCCC
>Mature Secondary Structure 
AQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AEREPVLSHVYQSYQHSHFPNFGGGVLGFYLLELSVPLISLFGVCIITILLLCSSVILLT
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NHQHRDVAKVALENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SDFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFDAENSSNNIVNHNQADQQEQLTEQT
HHHHHCCCCCCCCEECCCCCCCCHHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
HNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVN
HHCCCCHHHHHHCCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAKDVRIEAPIPGRSAVGIEV
CEEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCEEEEEEECCEEEECCCCCCCEEEEEC
PNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVC
CCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCHHH
INGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEM
HHHHHHHHHHCCCCCEEEEEEECCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHH
ERRYDLFQHSSTRNIKGYNELIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCHHHHHH
IQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEK
HHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECCCHHH
LLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEM
HHCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQV
CCHHHHHCCEEEEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
LIDLNNDEV
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA