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The map label for this gene is trxB

Identifier: 82750469

GI number: 82750469

Start: 788917

End: 789852

Strand: Direct

Name: trxB

Synonym: SAB0717

Alternate gene names: 82750469

Gene position: 788917-789852 (Clockwise)

Preceding gene: 82750468

Following gene: 82750471

Centisome position: 28.77

GC content: 37.39

Gene sequence:

>936_bases
ATGACTGAAATAGATTTTGATATAGCAATTATCGGTGCAGGTCCAGCTGGTATGACTGCTGCAGTATACGCATCACGTGC
TAATTTAAAAACAGTTATGATTGAAAGAGGTATTCCAGGCGGTCAAATGGCTAATACAGAAGAAGTAGAGAACTTCCCTG
GTTTCGAAATGATTACAGGTCCAGATTTATCTACAAAAATGTTTGAACACGCTAAAAAGTTTGGTGCAGTTTATCAATAT
GGAGATATTAAATCTGTAGAAGATAAAGGCGAATATAAAGTGATTAACTTTGGTAACAAAGAATTAACAGCTAAAGCGGT
CATTATTGCTACAGGTGCAGAATACAAGAAAATTGGTGTTCCGGGTGAACAAGAACTTGGTGGACGCGGTGTAAGTTATT
GTGCAGTATGTGATGGTGCATTCTTTAAAAATAAACGCCTATTCGTTATCGGTGGTGGTGACTCAGCAGTAGAAGAGGGA
ACATTCTTAACTAAATTTGCTGACAAAATAACAATCGTTCACCGTCGTGATGAGTTACGTGCACAGCGTATTTTACAAGA
TAGAGCATTCAAAAATGATAAAATCGACTTTATTTGGAGTCATACTTTGAAATCAATTAATGAAAAAGACGGCAAAGTGG
GTTCTGTGACATTAACGTCTACAAAAGATGGTTCAGAAGAAACACACGAGGTTGATGGTGTATTCATCTATATTGGTATG
AAACCATTAACAGCGCCATTTAAAGACTTAGGTATTACAAATGATGTTGGTTATATTGTGACAAAAGATGATATGACAAC
ATCAGTACCGGGTATTTTTGCAGCAGGAGATGTTCGCGACAAAGGTTTACGCCAAATTGTCACTGCTACTGGCGATGGTA
GTATTGCAGCGCAAAGTGCAGCGGAATATATTGAACATTTAAACGATCAAGCTTAA

Upstream 100 bases:

>100_bases
GAACAAAATGATTGAATTTCTCTTGAGCATATAGATTTATGAAAAGTTAGATTTATTATATAATGCGCATAATGATTAAT
AATGAGGAGGCGTTAATAAA

Downstream 100 bases:

>100_bases
TTCGAAGTCGAATTAAGATGTTGAGCTGTAAATTATTTGGATATTTATTTTAATAGTGTCATCACATTGTTAAAATAATG
TCTTACTTTTAAATTAAAGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQY
GDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEG
TFLTKFADKITIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEVDGVFIYIGM
KPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA

Sequences:

>Translated_311_residues
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQY
GDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEG
TFLTKFADKITIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEVDGVFIYIGM
KPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>Mature_310_residues
TEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYG
DIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGT
FLTKFADKITIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEVDGVFIYIGMK
PLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=41.85303514377, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=31.4754098360656, Blast_Score=141, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=41.4012738853503, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=41.2698412698413, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33659; Mature: 33527

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITG
CCEEEEEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEC
PDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGV
CCCHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCEEEECC
PGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKITIVHRRDELR
CCCHHHCCCCCEEEEEECCCEECCCEEEEEECCCCCHHCCCHHEEHHCEEEEEECHHHHH
AQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEVDGVFIYIGM
HHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCEEEEEEEC
KPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSA
CCCCCCHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHEEEEECCCCCCHHHHH
AEYIEHLNDQA
HHHHHHHCCCC
>Mature Secondary Structure 
TEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITG
CEEEEEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEC
PDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGV
CCCHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCEEEECC
PGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKITIVHRRDELR
CCCHHHCCCCCEEEEEECCCEECCCEEEEEECCCCCHHCCCHHEEHHCEEEEEECHHHHH
AQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEVDGVFIYIGM
HHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCEEEEEEEC
KPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSA
CCCCCCHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHEEEEECCCCCCHHHHH
AEYIEHLNDQA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA