Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 82703832

GI number: 82703832

Start: 3119408

End: 3120451

Strand: Reverse

Name: ruvB

Synonym: Nmul_A2719

Alternate gene names: 82703832

Gene position: 3120451-3119408 (Counterclockwise)

Preceding gene: 82703833

Following gene: 82703831

Centisome position: 98.0

GC content: 57.95

Gene sequence:

>1044_bases
ATGATAGAAACAGACCGCTTGATTACCCCTGCGCCCCTCTCGTTAAAAGAAGAGGATCTGGAGCGGGCGCTGCGGCCGAA
GCATCTGGCCGAATACATAGGCCAGGAAAAAATTCGCGGACAGCTACAGATATTCATCGAGGCAGCCAGGCGGCGCAGGG
AAGCGCTCGATCATGTACTGCTGTTTGGTCCGCCCGGCCTTGGTAAAACCACCCTTGCGCACATCGTTGCCAAGGAGATG
GGCGTGGGGCTGCGCCAGACCTCCGGCCCAGTGTTGGAACGTCCCGGCGATCTTGCGGCCCTGCTGACCAATCTCGAGCC
CAACGATGTTTTGTTCATAGATGAAATCCATCGTCTCTCCCCGGTCGTGGAGGAAATTCTCTATCCCGCACTGGAGGATT
ACCAGCTAGACATCATGATCGGCGAAGGCCCTGCGGCCCGTTCGGTCAAGCTTGATTTGCCGCCTTTTACCCTGGTCGGC
GCAACGACCCGCGCCGGAATGTTGACCAATCCGCTGCGCGATCGTTTTGGCATCATTTCGCGCCTGGAATTTTACTCCGT
CGAAGAACTCACCCAGATCGTCATGCGTTCCGCTGCATTGTTGGGAGCAGACATCTCTCCCGATGGCGCCACTGAAATTG
CGCGCCGTTCGCGTGGAACGCCTCGCGTTGTCAATCGTCTTCTACGACGTGTGCGTGACTTCGCGGAAGTCAAGGCGGAG
GGCCGTATCAACCGCCAGGTGGCCGACGCTGCCCTGCTCATGCTGGATGTGGATGCAATCGGACTCGATGTGATGGATAG
AAAGCTGCTCCTTACCGTAATGGAAAAATTCGGCGGCGGTCCGGTCGGTGTCGATAACCTCGCCGCCGCCATCAGCGAAG
AGCGCGGAACCATAGAAGACGTGCTCGAGCCCTATCTGATCCAGCAAGGATATATGAAGCGCACGCCGCGCGGACGGATG
GCGACGTCCATCGCGTATCAGCATTTTGGTCTGGCCCTGCCAAGGAATGGACTCAGCGCGGATTTGTGGGATGAGAAGCA
GTAG

Upstream 100 bases:

>100_bases
TCGGCGGTGGGGAAAGCCTGTCCTTCAGATTATCGCTCCGGTCGCCGATTCAATTCGATCAGCAGAAAACCTGGCGGAGA
TAGCGCTTTTTGAATTGGGA

Downstream 100 bases:

>100_bases
TAAATTTTCCGTGATGCAATCGTAGTAGCCGGCAGCTGGTCGCGATGTCGGCATCGATTTCTCAATTGATCAGATGAAGA
TGTCTTACTCAAGTCCCGAG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MIETDRLITPAPLSLKEEDLERALRPKHLAEYIGQEKIRGQLQIFIEAARRRREALDHVLLFGPPGLGKTTLAHIVAKEM
GVGLRQTSGPVLERPGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPALEDYQLDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIISRLEFYSVEELTQIVMRSAALLGADISPDGATEIARRSRGTPRVVNRLLRRVRDFAEVKAE
GRINRQVADAALLMLDVDAIGLDVMDRKLLLTVMEKFGGGPVGVDNLAAAISEERGTIEDVLEPYLIQQGYMKRTPRGRM
ATSIAYQHFGLALPRNGLSADLWDEKQ

Sequences:

>Translated_347_residues
MIETDRLITPAPLSLKEEDLERALRPKHLAEYIGQEKIRGQLQIFIEAARRRREALDHVLLFGPPGLGKTTLAHIVAKEM
GVGLRQTSGPVLERPGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPALEDYQLDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIISRLEFYSVEELTQIVMRSAALLGADISPDGATEIARRSRGTPRVVNRLLRRVRDFAEVKAE
GRINRQVADAALLMLDVDAIGLDVMDRKLLLTVMEKFGGGPVGVDNLAAAISEERGTIEDVLEPYLIQQGYMKRTPRGRM
ATSIAYQHFGLALPRNGLSADLWDEKQ
>Mature_347_residues
MIETDRLITPAPLSLKEEDLERALRPKHLAEYIGQEKIRGQLQIFIEAARRRREALDHVLLFGPPGLGKTTLAHIVAKEM
GVGLRQTSGPVLERPGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPALEDYQLDIMIGEGPAARSVKLDLPPFTLVG
ATTRAGMLTNPLRDRFGIISRLEFYSVEELTQIVMRSAALLGADISPDGATEIARRSRGTPRVVNRLLRRVRDFAEVKAE
GRINRQVADAALLMLDVDAIGLDVMDRKLLLTVMEKFGGGPVGVDNLAAAISEERGTIEDVLEPYLIQQGYMKRTPRGRM
ATSIAYQHFGLALPRNGLSADLWDEKQ

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=71.8562874251497, Blast_Score=483, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_NITMU (Q2Y5G5)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413398.1
- ProteinModelPortal:   Q2Y5G5
- SMR:   Q2Y5G5
- STRING:   Q2Y5G5
- GeneID:   3785884
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2719
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q2Y5G5
- ProtClustDB:   PRK00080
- BioCyc:   NMUL323848:NMUL_A2719-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38453; Mature: 38453

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDRLITPAPLSLKEEDLERALRPKHLAEYIGQEKIRGQLQIFIEAARRRREALDHVL
CCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LFGPPGLGKTTLAHIVAKEMGVGLRQTSGPVLERPGDLAALLTNLEPNDVLFIDEIHRLS
EECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHHH
PVVEEILYPALEDYQLDIMIGEGPAARSVKLDLPPFTLVGATTRAGMLTNPLRDRFGIIS
HHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEECCCHHCCHHHHHHHHHHHHHH
RLEFYSVEELTQIVMRSAALLGADISPDGATEIARRSRGTPRVVNRLLRRVRDFAEVKAE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GRINRQVADAALLMLDVDAIGLDVMDRKLLLTVMEKFGGGPVGVDNLAAAISEERGTIED
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
VLEPYLIQQGYMKRTPRGRMATSIAYQHFGLALPRNGLSADLWDEKQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIETDRLITPAPLSLKEEDLERALRPKHLAEYIGQEKIRGQLQIFIEAARRRREALDHVL
CCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LFGPPGLGKTTLAHIVAKEMGVGLRQTSGPVLERPGDLAALLTNLEPNDVLFIDEIHRLS
EECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEHHHHHHHH
PVVEEILYPALEDYQLDIMIGEGPAARSVKLDLPPFTLVGATTRAGMLTNPLRDRFGIIS
HHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCEEEECCCHHCCHHHHHHHHHHHHHH
RLEFYSVEELTQIVMRSAALLGADISPDGATEIARRSRGTPRVVNRLLRRVRDFAEVKAE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
GRINRQVADAALLMLDVDAIGLDVMDRKLLLTVMEKFGGGPVGVDNLAAAISEERGTIED
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
VLEPYLIQQGYMKRTPRGRMATSIAYQHFGLALPRNGLSADLWDEKQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA