Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 82703833

GI number: 82703833

Start: 3120560

End: 3121153

Strand: Reverse

Name: ruvA

Synonym: Nmul_A2720

Alternate gene names: 82703833

Gene position: 3121153-3120560 (Counterclockwise)

Preceding gene: 82703834

Following gene: 82703832

Centisome position: 98.02

GC content: 56.23

Gene sequence:

>594_bases
ATGATCGGGAGAATAAGCGGACTCCTGCTGGAAAAATTTCCCCCGCTGGTGCTGGTTGATGTCCAGGGTGTGGGCTATGA
GATCGACGTACCCATGAGCACGTTCTACAACCTGCCGGCCGTCGGGACGCAAATCACGCTCCACACTCATTTCGTCGTAC
GCGAAGACGCGCATTTGCTTTTCGGTTTCGCTACGGAAGGCGAGCGGCAGGCATTTCGCCAGCTCGTAAAAATTTCCGGT
GTTGGGGCGAGAACCGCGCTGGCTTTGCTATCCGGTCTGAGCGTGGCTGACTTGCATCAGACAGTGTCCAATCAGGATCC
TGCCCGTCTGATCAGGATTCCCGGCATCGGCAAGAAGACGGCAGAGCGCTTGCTGCTGGAATTGCGCGACAAGCTTGACT
TGGGCGTATCCGCGATTCCAGGCGCAGCGGGAGCCCGGCGGCCCTCAACGATGGGAAGCGATGTGCTGAATGCCCTGTTG
TCTCTAGGGTATAATGATCGCGAGGCCAATTGGGCGGTCAGTCAGCTATCCGTGGATCTTTCCGTTTCGGACGGCATAAG
ACAGGCACTGAAGTTCTTGTCAAAAGAGAAATAA

Upstream 100 bases:

>100_bases
CCGCCGATGCCCTTGCCTGTGCTATTTGCCATGCCCATGGAGGCTTGGGACTGGGTGCCCTGTCGACCGCCGGTTACCGG
GTAAAACAGGGGCGTCTCAT

Downstream 100 bases:

>100_bases
CGTCTTTGTCGGCGGTGGGGAAAGCCTGTCCTTCAGATTATCGCTCCGGTCGCCGATTCAATTCGATCAGCAGAAAACCT
GGCGGAGATAGCGCTTTTTG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLLFGFATEGERQAFRQLVKISG
VGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKTAERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALL
SLGYNDREANWAVSQLSVDLSVSDGIRQALKFLSKEK

Sequences:

>Translated_197_residues
MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLLFGFATEGERQAFRQLVKISG
VGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKTAERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALL
SLGYNDREANWAVSQLSVDLSVSDGIRQALKFLSKEK
>Mature_197_residues
MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLLFGFATEGERQAFRQLVKISG
VGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKTAERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALL
SLGYNDREANWAVSQLSVDLSVSDGIRQALKFLSKEK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=200, Percent_Identity=44, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_NITMU (Q2Y5G4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413399.1
- HSSP:   P40832
- ProteinModelPortal:   Q2Y5G4
- SMR:   Q2Y5G4
- STRING:   Q2Y5G4
- GeneID:   3785885
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2720
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q2Y5G4
- ProtClustDB:   PRK00116
- BioCyc:   NMUL323848:NMUL_A2720-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21257; Mature: 21257

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLL
CCCCHHHHHHHHCCCEEEEEECCCCEEEECCHHHHHCCCCCCEEEEEEEEEEEECCCEEE
FGFATEGERQAFRQLVKISGVGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKT
EEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCHHH
AERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALLSLGYNDREANWAVSQLSVDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEHEEEEE
SVSDGIRQALKFLSKEK
EHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGRISGLLLEKFPPLVLVDVQGVGYEIDVPMSTFYNLPAVGTQITLHTHFVVREDAHLL
CCCCHHHHHHHHCCCEEEEEECCCCEEEECCHHHHHCCCCCCEEEEEEEEEEEECCCEEE
FGFATEGERQAFRQLVKISGVGARTALALLSGLSVADLHQTVSNQDPARLIRIPGIGKKT
EEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCCHHH
AERLLLELRDKLDLGVSAIPGAAGARRPSTMGSDVLNALLSLGYNDREANWAVSQLSVDL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEHEEEEE
SVSDGIRQALKFLSKEK
EHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA