Click here to switch to the map view.

The map label for this gene is ubiA

Identifier: 82703724

GI number: 82703724

Start: 2997023

End: 2997895

Strand: Reverse

Name: ubiA

Synonym: Nmul_A2611

Alternate gene names: 82703724

Gene position: 2997895-2997023 (Counterclockwise)

Preceding gene: 82703725

Following gene: 82703723

Centisome position: 94.15

GC content: 58.53

Gene sequence:

>873_bases
GTGACACTCACTCAACGTCTCGTGCATTACGAAAAGCTGATGCGGCTGGACAAGCCCATCGGCATTCTGCTGCTGTTGTG
GCCCACGCTATGGGGCTTGTGGCTGGCAGCGGAAGGTGTGCCGCGGTTGGATATCCTGTTGATATTCGTGCTGGGGACGG
TGCTGATGCGCTCCGCCGGTTGTGTCGTCAACGACTATGCTGATCGCAATTTCGATGGACATGTCGAGCGTACCCGGACC
CGCCCCCTGGCACTTGGAGCGGTGAGCACCAGGGAAGCGCTGCTGCTGGCTGCAGGGTTGAGCCTCGTGGCGTTCCTGCT
GATCCAGCCGCTGAACCGGCTTACCATCGAGCTTTCGTTTGTCGCCCTGTTCCTGGCCGCAAGCTACCCTTTCACCAAGC
GGTTTTTTGCCATGCCGCAGGCTTACCTCGGCATCGCCTTCAGCTTTGGCATCCCCATGGCATTCGCCGCCCAGACCGGG
GAAGTGCCGTTTCCTGCCTGGTTCCTGATGGGTGCAAACCTGTTGTGGGTGATCGCCTACGATACCGAATACGCCATGGT
GGACAAGGTGGACGATCTCCGGATCGGCATCAAGACTTCCGCCATCACGTTCGGACGTTTCGACGTCGTCGGTGTGGTGT
TGTGCCATATGGCTTTCCTCGCGGGCATGGTTGCCATCGGCCTGCTGCAGAATCTCGGTGTCATTTATTACATTGGCCTG
GCCACAGCGCTGGGACTCATCCTGTATCAATACCGCCTGATCCACGACCGCGACCGCGCGCGCTGCTTCAAGGCTTTTCT
CCACAACAACTGGGTGGGTGCGACGATATTTGCCGGTATCGTGCTGGATTACTTGGTAAGAGCGGCTTCTTAA

Upstream 100 bases:

>100_bases
TGCAGCCGGGGAATCTGTGGGCGCGTCGCTCCCTGTTCACGCTGCATGGCCAGTCCATACTGGTTACCGAAGTATTCCTT
CCTTCCATCCTGGAGCTTGC

Downstream 100 bases:

>100_bases
GGTTTCCGGACGTAAAGGGCGTAAATGAAGTACAAGGACCTGCGCGATTTTCTTGCGCAACTCGAAAGACAGGGCGAGCT
GAAACGCGTGGCAGTCGAGA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTLTQRLVHYEKLMRLDKPIGILLLLWPTLWGLWLAAEGVPRLDILLIFVLGTVLMRSAGCVVNDYADRNFDGHVERTRT
RPLALGAVSTREALLLAAGLSLVAFLLIQPLNRLTIELSFVALFLAASYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTG
EVPFPAWFLMGANLLWVIAYDTEYAMVDKVDDLRIGIKTSAITFGRFDVVGVVLCHMAFLAGMVAIGLLQNLGVIYYIGL
ATALGLILYQYRLIHDRDRARCFKAFLHNNWVGATIFAGIVLDYLVRAAS

Sequences:

>Translated_290_residues
MTLTQRLVHYEKLMRLDKPIGILLLLWPTLWGLWLAAEGVPRLDILLIFVLGTVLMRSAGCVVNDYADRNFDGHVERTRT
RPLALGAVSTREALLLAAGLSLVAFLLIQPLNRLTIELSFVALFLAASYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTG
EVPFPAWFLMGANLLWVIAYDTEYAMVDKVDDLRIGIKTSAITFGRFDVVGVVLCHMAFLAGMVAIGLLQNLGVIYYIGL
ATALGLILYQYRLIHDRDRARCFKAFLHNNWVGATIFAGIVLDYLVRAAS
>Mature_289_residues
TLTQRLVHYEKLMRLDKPIGILLLLWPTLWGLWLAAEGVPRLDILLIFVLGTVLMRSAGCVVNDYADRNFDGHVERTRTR
PLALGAVSTREALLLAAGLSLVAFLLIQPLNRLTIELSFVALFLAASYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGE
VPFPAWFLMGANLLWVIAYDTEYAMVDKVDDLRIGIKTSAITFGRFDVVGVVLCHMAFLAGMVAIGLLQNLGVIYYIGLA
TALGLILYQYRLIHDRDRARCFKAFLHNNWVGATIFAGIVLDYLVRAAS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=285, Percent_Identity=34.3859649122807, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=53.8732394366197, Blast_Score=290, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17553718, Length=285, Percent_Identity=35.7894736842105, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=285, Percent_Identity=34.0350877192982, Blast_Score=157, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=183, Percent_Identity=38.2513661202186, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=42.5531914893617, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=137, Percent_Identity=42.3357664233577, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=32.2033898305085, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=38.86925795053, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_NITMU (Q2Y5S3)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413290.1
- STRING:   Q2Y5S3
- GeneID:   3786240
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2611
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- PhylomeDB:   Q2Y5S3
- ProtClustDB:   PRK12848
- BioCyc:   NMUL323848:NMUL_A2611-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32240; Mature: 32109

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14fe5b50)-; HASH(0x10819800)-; HASH(0x159dbeec)-; HASH(0x15b7ca00)-; HASH(0x157c1a74)-; HASH(0x14cb41b8)-; HASH(0x159e05f4)-; HASH(0x15eb42a0)-; HASH(0x1514af9c)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTQRLVHYEKLMRLDKPIGILLLLWPTLWGLWLAAEGVPRLDILLIFVLGTVLMRSAG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
CVVNDYADRNFDGHVERTRTRPLALGAVSTREALLLAAGLSLVAFLLIQPLNRLTIELSF
CEEECCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
VALFLAASYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGEVPFPAWFLMGANLLWVIAY
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCCEEEEEEE
DTEYAMVDKVDDLRIGIKTSAITFGRFDVVGVVLCHMAFLAGMVAIGLLQNLGVIYYIGL
CCCCHHHCCCCHHEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ATALGLILYQYRLIHDRDRARCFKAFLHNNWVGATIFAGIVLDYLVRAAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TLTQRLVHYEKLMRLDKPIGILLLLWPTLWGLWLAAEGVPRLDILLIFVLGTVLMRSAG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
CVVNDYADRNFDGHVERTRTRPLALGAVSTREALLLAAGLSLVAFLLIQPLNRLTIELSF
CEEECCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
VALFLAASYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGEVPFPAWFLMGANLLWVIAY
HHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCCEEEEEEE
DTEYAMVDKVDDLRIGIKTSAITFGRFDVVGVVLCHMAFLAGMVAIGLLQNLGVIYYIGL
CCCCHHHCCCCHHEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ATALGLILYQYRLIHDRDRARCFKAFLHNNWVGATIFAGIVLDYLVRAAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA