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The map label for this gene is ubiC

Identifier: 82703725

GI number: 82703725

Start: 2997892

End: 2998434

Strand: Reverse

Name: ubiC

Synonym: Nmul_A2612

Alternate gene names: 82703725

Gene position: 2998434-2997892 (Counterclockwise)

Preceding gene: 82703726

Following gene: 82703724

Centisome position: 94.16

GC content: 58.75

Gene sequence:

>543_bases
ATGAATGCTGCCCAGCTATCGGACTGGCATCCTGCACCTTCCTCCATATCGCCCCGCGCCCGGGGCTGGTTGCAAAATCG
CGGCTCTCTTACCCAGCTTATTCAGCGCCGCTGCTGCAGTGAGTTCAGTGTCAAGCCAGTGTTCCAGTCGTTGGCAACGG
TCTGCGACGATGAACTGGCCGTAATGAATTTACGGCGGGATGAACTGGCCCTGGTGCGGGAAGTGTATTTATATTGCGGC
GAGACGCCGGTTGTCTTTGCCCATTCCGTGGTGGCGCGGAAACATTTGCGCGGCGCATGGCGCAGCCTGATCGGACTGGG
CAACAAGTCGCTGGGGACAGTGTTATTTACCAATCCTGTCGTCAAGCGTACACCGCTCCGCTTCAAGAAGCTGACTGCGG
CTCATCCGCTTTTCAGCCGCGCCTGCCGCAAGTTGCGGGTGCAGCCGGGGAATCTGTGGGCGCGTCGCTCCCTGTTCACG
CTGCATGGCCAGTCCATACTGGTTACCGAAGTATTCCTTCCTTCCATCCTGGAGCTTGCGTGA

Upstream 100 bases:

>100_bases
GCTTTCTACAATTCTCAGGCCGGTTTGGTGAAATATCCGGGCTAAGGATTCAGCCGGGCTGGATTATGGGGCATAATTCA
CTCTTTTCAGCTCTTCCGGA

Downstream 100 bases:

>100_bases
CACTCACTCAACGTCTCGTGCATTACGAAAAGCTGATGCGGCTGGACAAGCCCATCGGCATTCTGCTGCTGTTGTGGCCC
ACGCTATGGGGCTTGTGGCT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELAVMNLRRDELALVREVYLYCG
ETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPVVKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFT
LHGQSILVTEVFLPSILELA

Sequences:

>Translated_180_residues
MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELAVMNLRRDELALVREVYLYCG
ETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPVVKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFT
LHGQSILVTEVFLPSILELA
>Mature_180_residues
MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELAVMNLRRDELALVREVYLYCG
ETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPVVKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFT
LHGQSILVTEVFLPSILELA

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_NITMU (Q2Y5S2)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413291.1
- ProteinModelPortal:   Q2Y5S2
- SMR:   Q2Y5S2
- STRING:   Q2Y5S2
- GeneID:   3786241
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2612
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   EVCHYPE
- ProtClustDB:   CLSK585969
- BioCyc:   NMUL323848:NMUL_A2612-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20246; Mature: 20246

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: NA

Important sites: BINDING 73-73 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHH
VMNLRRDELALVREVYLYCGETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPV
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
VKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFTLHGQSILVTEVFLPSILELA
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAAQLSDWHPAPSSISPRARGWLQNRGSLTQLIQRRCCSEFSVKPVFQSLATVCDDELA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHH
VMNLRRDELALVREVYLYCGETPVVFAHSVVARKHLRGAWRSLIGLGNKSLGTVLFTNPV
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
VKRTPLRFKKLTAAHPLFSRACRKLRVQPGNLWARRSLFTLHGQSILVTEVFLPSILELA
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA