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The map label for this gene is crtB [H]

Identifier: 82703460

GI number: 82703460

Start: 2670156

End: 2670998

Strand: Reverse

Name: crtB [H]

Synonym: Nmul_A2343

Alternate gene names: 82703460

Gene position: 2670998-2670156 (Counterclockwise)

Preceding gene: 82703461

Following gene: 82703459

Centisome position: 83.88

GC content: 53.62

Gene sequence:

>843_bases
ATGACACCTGACCAGTATTGCCAGGAAAAAGCTGTTCAAAGCGGTTCGAGCTTCTACTACAGCTTTCTCTATCTGCCCCC
TGAGAGGCGTCGTGCCATTACTGCACTCTACGCTTTTTGTCGAGAGGTGGACGATGTCGTGGACGAGTGTACGGAAGCAT
CAGTAGCGCGAGTAAAGCTTGCATGGTGGCGACAGGAAGTTGCTGCGATCTTCGATGCAGGGGGAAACAAGCCCAGCCAC
CCCGTGGCACAGGCATTGGCAGGCGTGGCAAGCACGTTCAATCTGACCGCAGACCGTCTGAACGAGATCATAGACGGTAT
GGAAATGGATCTCGATTATAACCGCTACGCAGATTTCGATACCCTTCGGCACTACTGTTACCATGTGGCAAGCGTAGTGG
GATTATGCTCCGCTGAGATATTCGGCTACCGCAATCCGAAAACGCTCGAATATGCCCAGGATCTCGGGCTGGCATTCCAG
CTTACCAATATCATACGCGACGTCGGCGAGGATGCCCGGCGCGACCGTATTTATCTGCCTCAGGACGAGCTCGCGCGCTT
CGGGGTGAGCAATGAAGATATACTCCAGTCGCGTGAAACAGACAATTTCCGGCGTTTAATCGAATTTCAGATCGACCGGG
CGGAAAGTTATTATGCAAACGCTTTTGCGGCGCTGCCGGAGGAGGATCGCAAAAGCCAGCGTTCCGGGATCATCATGGCG
GCGATCTATCAGGCCTTGCTGAAGGAGATCAAGGCTGATGGATGTCATGTGATGCGGCAGCGTATAAGCCTCACGCCGCT
GCGTAAGCTCTGGATAGCATGGAAAACCTGGATGAAAGGATGA

Upstream 100 bases:

>100_bases
CGGGGAACGCAGCGACAAGTGTGATTGATGAGATAATGTGCTTTTTTTGCTTCAGCGAGGGCTCAGCGATGACAAATTAT
CGCCTTTTTAATAATTTATC

Downstream 100 bases:

>100_bases
AGCGTTATTCCCGCGCTACCCAAAGGCACTTTCCATGGAGCCTTCATCGCTGTAAACCGGGAGCAACCTCTTAACGGAAT
TTGTTTCCAGCCGTAAGTAT

Product: squalene/phytoene synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTPDQYCQEKAVQSGSSFYYSFLYLPPERRRAITALYAFCREVDDVVDECTEASVARVKLAWWRQEVAAIFDAGGNKPSH
PVAQALAGVASTFNLTADRLNEIIDGMEMDLDYNRYADFDTLRHYCYHVASVVGLCSAEIFGYRNPKTLEYAQDLGLAFQ
LTNIIRDVGEDARRDRIYLPQDELARFGVSNEDILQSRETDNFRRLIEFQIDRAESYYANAFAALPEEDRKSQRSGIIMA
AIYQALLKEIKADGCHVMRQRISLTPLRKLWIAWKTWMKG

Sequences:

>Translated_280_residues
MTPDQYCQEKAVQSGSSFYYSFLYLPPERRRAITALYAFCREVDDVVDECTEASVARVKLAWWRQEVAAIFDAGGNKPSH
PVAQALAGVASTFNLTADRLNEIIDGMEMDLDYNRYADFDTLRHYCYHVASVVGLCSAEIFGYRNPKTLEYAQDLGLAFQ
LTNIIRDVGEDARRDRIYLPQDELARFGVSNEDILQSRETDNFRRLIEFQIDRAESYYANAFAALPEEDRKSQRSGIIMA
AIYQALLKEIKADGCHVMRQRISLTPLRKLWIAWKTWMKG
>Mature_279_residues
TPDQYCQEKAVQSGSSFYYSFLYLPPERRRAITALYAFCREVDDVVDECTEASVARVKLAWWRQEVAAIFDAGGNKPSHP
VAQALAGVASTFNLTADRLNEIIDGMEMDLDYNRYADFDTLRHYCYHVASVVGLCSAEIFGYRNPKTLEYAQDLGLAFQL
TNIIRDVGEDARRDRIYLPQDELARFGVSNEDILQSRETDNFRRLIEFQIDRAESYYANAFAALPEEDRKSQRSGIIMAA
IYQALLKEIKADGCHVMRQRISLTPLRKLWIAWKTWMKG

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=204, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 32146; Mature: 32014

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1 ; PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDQYCQEKAVQSGSSFYYSFLYLPPERRRAITALYAFCREVDDVVDECTEASVARVKL
CCCHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWWRQEVAAIFDAGGNKPSHPVAQALAGVASTFNLTADRLNEIIDGMEMDLDYNRYADFD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHCCCHH
TLRHYCYHVASVVGLCSAEIFGYRNPKTLEYAQDLGLAFQLTNIIRDVGEDARRDRIYLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QDELARFGVSNEDILQSRETDNFRRLIEFQIDRAESYYANAFAALPEEDRKSQRSGIIMA
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHH
AIYQALLKEIKADGCHVMRQRISLTPLRKLWIAWKTWMKG
HHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPDQYCQEKAVQSGSSFYYSFLYLPPERRRAITALYAFCREVDDVVDECTEASVARVKL
CCHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWWRQEVAAIFDAGGNKPSHPVAQALAGVASTFNLTADRLNEIIDGMEMDLDYNRYADFD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHCCCHH
TLRHYCYHVASVVGLCSAEIFGYRNPKTLEYAQDLGLAFQLTNIIRDVGEDARRDRIYLP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QDELARFGVSNEDILQSRETDNFRRLIEFQIDRAESYYANAFAALPEEDRKSQRSGIIMA
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHH
AIYQALLKEIKADGCHVMRQRISLTPLRKLWIAWKTWMKG
HHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018713; 8905231 [H]