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The map label for this gene is trpB

Identifier: 82703033

GI number: 82703033

Start: 2202271

End: 2203467

Strand: Reverse

Name: trpB

Synonym: Nmul_A1912

Alternate gene names: 82703033

Gene position: 2203467-2202271 (Counterclockwise)

Preceding gene: 82703034

Following gene: 82703032

Centisome position: 69.2

GC content: 59.15

Gene sequence:

>1197_bases
GTGAAAGTCTATGATCTTCCGGACAGTCATGGGCACTTTGGTCCGTATGGCGGCATCTTTGTCGCTGAAACGCTGATCTC
GGCACTGGAGGATTTACGCATACAGTACGAGCGCTATCGCAGCGACGCCGACTTTCAGGCAGAATTCGCCCATGAACTCA
AGCATTATGTGGGACGCCCGACTCCCATCTATCATGCAAAACGATGGTCTGCGCAGCTGGGGGGCGCCCAGATCCTGCTC
AAGCGCGAGGACCTGAACCATACGGGCGCCCACAAAATCAATAATGCGATGGGACAGGCGCTGCTGGCAAGGCGCATGGG
CAAATCGCGGGTAATAGCCGAGACCGGCGCAGGCCAGCATGGTGTTGCCACGGCCACGGTCGCAGCGCGGTATGGGATGG
AGTGTGTCATCTACATGGGATCGGTCGATGTGGAGCGCCAGGCTGCCAATGTTTACCGGATGAAGCTTCTGGGTGCGGAG
GTCATACCGGTCGAATCCGGCTCACGCACGCTGAAGGATGCTTTGAACGAGGCCATGCGCGACTGGGTGACCAATGTTGC
GGATACCTTTTACATCATCGGTACTGTGGCCGGACCTCATCCCTATCCCATGATGGTACGGGATTTCCAGGCGATCATCG
GGCGCGAGGCCATAACCCAGATGCAGGAGGATTACGGACGGCAGCCCGATGCCCTGATCGCCTGCGTGGGGGGGGGGTCA
AATGCCATCGGGCTTTTTTATCCCTACCTCGACAGCAGCATCCGGATGATCGGAGTGGAAGCGGCCGGACACGGCGTGGA
GACGGATCAGCATGCCGCTACCCTGACGAAGGGACGCCCTGGCGTGTTGCACGGCAATCGCACTTACCTCATCCAGGATG
AGAATGGGCAGATCGTCGAAACACATTCCATTTCGGCAGGCCTGGATTATCCCGGCGTAGGGCCGGAGCATGCCTGGCTC
AAGGACAGCGGACGGGCCGAATATTTCGGAATAACCGACGAGCAGGCTCTGGAAGCCTTCCACGCACTGTGCCATTACGA
AGGGATCATTCCCGCGCTCGAATCCAGTCATGCGCTGGCTTATGCAGCCCGGCTCGCGCCTGCCCTCACTTCCGACAAGT
TGCTGCTGGTGAACCTCTCGGGGCGTGGGGACAAGGATATGCCCACCGTGGCGCGCGCTTCGCATATCACCTTCTAA

Upstream 100 bases:

>100_bases
GCCCATCCTTGGGCGGTGGATGTGTCCAGTGGCGTGGAAGCCGCGAAGGGCATTAAAGATTCGGGGAAAATTGCAGCATT
CATGCGAGGAGTTGGAATCA

Downstream 100 bases:

>100_bases
CCTGCAAAGTCCATTCATGTCCCGTATTTCCACCCTGTTTGGCAAACTGCTCCAGAATCGGAGAAAGGCGCTCATTCCTT
TTATTACTGCTGGCGATCCC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKVYDLPDSHGHFGPYGGIFVAETLISALEDLRIQYERYRSDADFQAEFAHELKHYVGRPTPIYHAKRWSAQLGGAQILL
KREDLNHTGAHKINNAMGQALLARRMGKSRVIAETGAGQHGVATATVAARYGMECVIYMGSVDVERQAANVYRMKLLGAE
VIPVESGSRTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAIIGREAITQMQEDYGRQPDALIACVGGGS
NAIGLFYPYLDSSIRMIGVEAAGHGVETDQHAATLTKGRPGVLHGNRTYLIQDENGQIVETHSISAGLDYPGVGPEHAWL
KDSGRAEYFGITDEQALEAFHALCHYEGIIPALESSHALAYAARLAPALTSDKLLLVNLSGRGDKDMPTVARASHITF

Sequences:

>Translated_398_residues
MKVYDLPDSHGHFGPYGGIFVAETLISALEDLRIQYERYRSDADFQAEFAHELKHYVGRPTPIYHAKRWSAQLGGAQILL
KREDLNHTGAHKINNAMGQALLARRMGKSRVIAETGAGQHGVATATVAARYGMECVIYMGSVDVERQAANVYRMKLLGAE
VIPVESGSRTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAIIGREAITQMQEDYGRQPDALIACVGGGS
NAIGLFYPYLDSSIRMIGVEAAGHGVETDQHAATLTKGRPGVLHGNRTYLIQDENGQIVETHSISAGLDYPGVGPEHAWL
KDSGRAEYFGITDEQALEAFHALCHYEGIIPALESSHALAYAARLAPALTSDKLLLVNLSGRGDKDMPTVARASHITF
>Mature_398_residues
MKVYDLPDSHGHFGPYGGIFVAETLISALEDLRIQYERYRSDADFQAEFAHELKHYVGRPTPIYHAKRWSAQLGGAQILL
KREDLNHTGAHKINNAMGQALLARRMGKSRVIAETGAGQHGVATATVAARYGMECVIYMGSVDVERQAANVYRMKLLGAE
VIPVESGSRTLKDALNEAMRDWVTNVADTFYIIGTVAGPHPYPMMVRDFQAIIGREAITQMQEDYGRQPDALIACVGGGS
NAIGLFYPYLDSSIRMIGVEAAGHGVETDQHAATLTKGRPGVLHGNRTYLIQDENGQIVETHSISAGLDYPGVGPEHAWL
KDSGRAEYFGITDEQALEAFHALCHYEGIIPALESSHALAYAARLAPALTSDKLLLVNLSGRGDKDMPTVARASHITF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=55.3805774278215, Blast_Score=428, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=393, Percent_Identity=53.4351145038168, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_NITMU (Q2Y7R4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412599.1
- HSSP:   P0A2K1
- ProteinModelPortal:   Q2Y7R4
- SMR:   Q2Y7R4
- STRING:   Q2Y7R4
- GeneID:   3784150
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1912
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- PhylomeDB:   Q2Y7R4
- ProtClustDB:   PRK04346
- BioCyc:   NMUL323848:NMUL_A1912-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43420; Mature: 43420

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYDLPDSHGHFGPYGGIFVAETLISALEDLRIQYERYRSDADFQAEFAHELKHYVGRP
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPIYHAKRWSAQLGGAQILLKREDLNHTGAHKINNAMGQALLARRMGKSRVIAETGAGQH
CCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GVATATVAARYGMECVIYMGSVDVERQAANVYRMKLLGAEVIPVESGSRTLKDALNEAMR
CCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
DWVTNVADTFYIIGTVAGPHPYPMMVRDFQAIIGREAITQMQEDYGRQPDALIACVGGGS
HHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NAIGLFYPYLDSSIRMIGVEAAGHGVETDQHAATLTKGRPGVLHGNRTYLIQDENGQIVE
CEEEEEEHHHCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCEEECCEEEEEECCCCCEEE
THSISAGLDYPGVGPEHAWLKDSGRAEYFGITDEQALEAFHALCHYEGIIPALESSHALA
EECCCCCCCCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YAARLAPALTSDKLLLVNLSGRGDKDMPTVARASHITF
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKVYDLPDSHGHFGPYGGIFVAETLISALEDLRIQYERYRSDADFQAEFAHELKHYVGRP
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPIYHAKRWSAQLGGAQILLKREDLNHTGAHKINNAMGQALLARRMGKSRVIAETGAGQH
CCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GVATATVAARYGMECVIYMGSVDVERQAANVYRMKLLGAEVIPVESGSRTLKDALNEAMR
CCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
DWVTNVADTFYIIGTVAGPHPYPMMVRDFQAIIGREAITQMQEDYGRQPDALIACVGGGS
HHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
NAIGLFYPYLDSSIRMIGVEAAGHGVETDQHAATLTKGRPGVLHGNRTYLIQDENGQIVE
CEEEEEEHHHCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCEEECCEEEEEECCCCCEEE
THSISAGLDYPGVGPEHAWLKDSGRAEYFGITDEQALEAFHALCHYEGIIPALESSHALA
EECCCCCCCCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YAARLAPALTSDKLLLVNLSGRGDKDMPTVARASHITF
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA