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The map label for this gene is acpS

Identifier: 82702883

GI number: 82702883

Start: 2011180

End: 2011557

Strand: Direct

Name: acpS

Synonym: Nmul_A1760

Alternate gene names: 82702883

Gene position: 2011180-2011557 (Clockwise)

Preceding gene: 82702882

Following gene: 82702884

Centisome position: 63.16

GC content: 52.38

Gene sequence:

>378_bases
ATGATCTATGGGATCGGAACCGATCTGGTTGAAACCTCGCGTATTACGCGCCTGCTGGAAAAATACGGAGAGCGTTTCGC
CCGGCGCCTGCTGACAGACGAGGAGTGGCCGGAATATGCAAAAAGCATGCAGCCCGCAATGTTCCTGGCAAAGCGTTTTG
CCGCCAAGGAAGCCCTCGCCAAAGCCTTTGGCACGGGTATCCGTCATCCTGTCAGCCTGAGCCATATCGGAGTAACCCAT
GATACCCTGGGCAAACCCTATTTCAAATTCCACCCTGAATTGCATACCCTCGTCCAAAACGAAGGCATCACCCGTCACCA
TCTCTCCATCAGTGACGAGTTGAACCTCGCTTGCGCTTTTGTCATATTGGAAAAATAA

Upstream 100 bases:

>100_bases
CGGAGCTCAACATCGGGCACGCGATCGTGGCTCGTGCATTGTTCGTGGGCTTCGAGCGGGCAGTCCGGGAAATGAAAAAC
CTGATGCTGGAAGCATGTAA

Downstream 100 bases:

>100_bases
ATGTCGCTCGGTCCCGTCATACTCGATATCGAAGGCACGCAACTCACCGCCAACGATAAGAAAAAACTCCGGCACCCGCT
GGTTGGAGGGGTGATCCTGT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIYGIGTDLVETSRITRLLEKYGERFARRLLTDEEWPEYAKSMQPAMFLAKRFAAKEALAKAFGTGIRHPVSLSHIGVTH
DTLGKPYFKFHPELHTLVQNEGITRHHLSISDELNLACAFVILEK

Sequences:

>Translated_125_residues
MIYGIGTDLVETSRITRLLEKYGERFARRLLTDEEWPEYAKSMQPAMFLAKRFAAKEALAKAFGTGIRHPVSLSHIGVTH
DTLGKPYFKFHPELHTLVQNEGITRHHLSISDELNLACAFVILEK
>Mature_125_residues
MIYGIGTDLVETSRITRLLEKYGERFARRLLTDEEWPEYAKSMQPAMFLAKRFAAKEALAKAFGTGIRHPVSLSHIGVTH
DTLGKPYFKFHPELHTLVQNEGITRHHLSISDELNLACAFVILEK

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=46.3414634146341, Blast_Score=120, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_NITMU (Q2Y864)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412449.1
- ProteinModelPortal:   Q2Y864
- SMR:   Q2Y864
- STRING:   Q2Y864
- GeneID:   3783960
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1760
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q2Y864
- ProtClustDB:   PRK00070
- BioCyc:   NMUL323848:NMUL_A1760-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14239; Mature: 14239

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGIGTDLVETSRITRLLEKYGERFARRLLTDEEWPEYAKSMQPAMFLAKRFAAKEALA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
KAFGTGIRHPVSLSHIGVTHDTLGKPYFKFHPELHTLVQNEGITRHHLSISDELNLACAF
HHHHCCCCCCCCHHHCCCCHHHCCCCCEEECHHHHHHHHCCCCCEEECCCCCCCCCEEEE
VILEK
EEECC
>Mature Secondary Structure
MIYGIGTDLVETSRITRLLEKYGERFARRLLTDEEWPEYAKSMQPAMFLAKRFAAKEALA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
KAFGTGIRHPVSLSHIGVTHDTLGKPYFKFHPELHTLVQNEGITRHHLSISDELNLACAF
HHHHCCCCCCCCHHHCCCCHHHCCCCCEEECHHHHHHHHCCCCCEEECCCCCCCCCEEEE
VILEK
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA