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The map label for this gene is nagZ

Identifier: 82702884

GI number: 82702884

Start: 2011558

End: 2012607

Strand: Direct

Name: nagZ

Synonym: Nmul_A1761

Alternate gene names: 82702884

Gene position: 2011558-2012607 (Clockwise)

Preceding gene: 82702883

Following gene: 82702885

Centisome position: 63.17

GC content: 57.43

Gene sequence:

>1050_bases
ATGTCGCTCGGTCCCGTCATACTCGATATCGAAGGCACGCAACTCACCGCCAACGATAAGAAAAAACTCCGGCACCCGCT
GGTTGGAGGGGTGATCCTGTTCACGCGCAACTATTCCTCGCTTGCGCAACTCATGCATCTGACTGCTGAAATCCATGCGC
TGCGAACGCCGCCACTCCTGGTCGCCGTCGATCACGAAGGAGGCAGAGTTCAACGTTTCCGGGAAGATTTCACGCGCCTG
CCCCCCATGCGAGAACTGGGCAGGATCTGGGATGAGCATCCTGCCCAGGCGCGGCATCTGGCGCATGAGGCGGGATATGT
CCTGGCGGCGGAACTACGGGCTGCGGGCGTGGACTTCAGTTTTACACCGGTCCTGGATATGGATTATGGCCAAAGCAGCG
TCATCCGCGACCGTGCTTTTCACCGTGACCCGCAAGCCATTGCCGAGCTGGCCCATAGCCTGATGAGCGGGTTGAAATCA
GCCGGAATGGCAGCGGTGGGCAAACATTTCCCTGGTCATGGTTATATCGAGGCCGATTCCCATTTCGAAATGCCGGTGGA
CGAACGAACTTACGCGCAGATCGAAATGGACGATCTTATTCCATTCCGTAAAATGATCGGTTTCGGCCTTACCGGCATGA
TGCCTGCCCACGTCATTTATCCAAAGGTGGATGCATTACCGGCCGGTTTTTCCGAAGTATGGCTCAAAAAGGTTTTGCGG
GGTGAGCTGGGTTTCGAAGGGTGTATCTTCAGCGACGATCTGAATATGGCGGGAGCAGCTTTTGCAGGCAATCCGGTGGA
GCGGGCCCAGAAAGCATTGCATGCGGGATGCGACATGGTGCTTCTGTGTAATAACCCGGAAGCGGCCGAAATGCTGCTCG
CGGAGCTACATTGGGACCTGCCCGCCCTTGGGGTGATTCGTCTCGCCCGCATGCGCGGGCGCCCAAACCCGGATTCGCTG
GTGAAACTGCACGAAAACCCGAACTTCGTCAGTGCCGTGGAAAAAATTGCGGGTATCGGCGTTCGCAGCGGCGAGTTGCC
GCTGGTGTAG

Upstream 100 bases:

>100_bases
ATTGCATACCCTCGTCCAAAACGAAGGCATCACCCGTCACCATCTCTCCATCAGTGACGAGTTGAACCTCGCTTGCGCTT
TTGTCATATTGGAAAAATAA

Downstream 100 bases:

>100_bases
CAAAATCTGAAACCCGCACCTTCCCTATCCCCGCCCTCCTGCCACAGCGGGTCTCCTCTGTTTTGCCACCCTCCTCCCCA
GCAGCAGCTCCAGCGTTCTC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSLGPVILDIEGTQLTANDKKKLRHPLVGGVILFTRNYSSLAQLMHLTAEIHALRTPPLLVAVDHEGGRVQRFREDFTRL
PPMRELGRIWDEHPAQARHLAHEAGYVLAAELRAAGVDFSFTPVLDMDYGQSSVIRDRAFHRDPQAIAELAHSLMSGLKS
AGMAAVGKHFPGHGYIEADSHFEMPVDERTYAQIEMDDLIPFRKMIGFGLTGMMPAHVIYPKVDALPAGFSEVWLKKVLR
GELGFEGCIFSDDLNMAGAAFAGNPVERAQKALHAGCDMVLLCNNPEAAEMLLAELHWDLPALGVIRLARMRGRPNPDSL
VKLHENPNFVSAVEKIAGIGVRSGELPLV

Sequences:

>Translated_349_residues
MSLGPVILDIEGTQLTANDKKKLRHPLVGGVILFTRNYSSLAQLMHLTAEIHALRTPPLLVAVDHEGGRVQRFREDFTRL
PPMRELGRIWDEHPAQARHLAHEAGYVLAAELRAAGVDFSFTPVLDMDYGQSSVIRDRAFHRDPQAIAELAHSLMSGLKS
AGMAAVGKHFPGHGYIEADSHFEMPVDERTYAQIEMDDLIPFRKMIGFGLTGMMPAHVIYPKVDALPAGFSEVWLKKVLR
GELGFEGCIFSDDLNMAGAAFAGNPVERAQKALHAGCDMVLLCNNPEAAEMLLAELHWDLPALGVIRLARMRGRPNPDSL
VKLHENPNFVSAVEKIAGIGVRSGELPLV
>Mature_348_residues
SLGPVILDIEGTQLTANDKKKLRHPLVGGVILFTRNYSSLAQLMHLTAEIHALRTPPLLVAVDHEGGRVQRFREDFTRLP
PMRELGRIWDEHPAQARHLAHEAGYVLAAELRAAGVDFSFTPVLDMDYGQSSVIRDRAFHRDPQAIAELAHSLMSGLKSA
GMAAVGKHFPGHGYIEADSHFEMPVDERTYAQIEMDDLIPFRKMIGFGLTGMMPAHVIYPKVDALPAGFSEVWLKKVLRG
ELGFEGCIFSDDLNMAGAAFAGNPVERAQKALHAGCDMVLLCNNPEAAEMLLAELHWDLPALGVIRLARMRGRPNPDSLV
KLHENPNFVSAVEKIAGIGVRSGELPLV

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=295, Percent_Identity=50.1694915254237, Blast_Score=278, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_NITMU (Q2Y863)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412450.1
- ProteinModelPortal:   Q2Y863
- SMR:   Q2Y863
- STRING:   Q2Y863
- GeneID:   3783961
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1761
- eggNOG:   COG1472
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- PhylomeDB:   Q2Y863
- ProtClustDB:   PRK05337
- BioCyc:   NMUL323848:NMUL_A1761-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 38355; Mature: 38224

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 252-252

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGPVILDIEGTQLTANDKKKLRHPLVGGVILFTRNYSSLAQLMHLTAEIHALRTPPLL
CCCCCEEEEECCCEECCCCHHHHHCCHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
VAVDHEGGRVQRFREDFTRLPPMRELGRIWDEHPAQARHLAHEAGYVLAAELRAAGVDFS
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHHCCCCCC
FTPVLDMDYGQSSVIRDRAFHRDPQAIAELAHSLMSGLKSAGMAAVGKHFPGHGYIEADS
CCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEECCC
HFEMPVDERTYAQIEMDDLIPFRKMIGFGLTGMMPAHVIYPKVDALPAGFSEVWLKKVLR
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHEECCCHHCCCCCHHHHHHHHHHH
GELGFEGCIFSDDLNMAGAAFAGNPVERAQKALHAGCDMVLLCNNPEAAEMLLAELHWDL
HCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCC
PALGVIRLARMRGRPNPDSLVKLHENPNFVSAVEKIAGIGVRSGELPLV
CHHHHHHHHHHCCCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLGPVILDIEGTQLTANDKKKLRHPLVGGVILFTRNYSSLAQLMHLTAEIHALRTPPLL
CCCCEEEEECCCEECCCCHHHHHCCHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
VAVDHEGGRVQRFREDFTRLPPMRELGRIWDEHPAQARHLAHEAGYVLAAELRAAGVDFS
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHHCCCCCC
FTPVLDMDYGQSSVIRDRAFHRDPQAIAELAHSLMSGLKSAGMAAVGKHFPGHGYIEADS
CCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEECCC
HFEMPVDERTYAQIEMDDLIPFRKMIGFGLTGMMPAHVIYPKVDALPAGFSEVWLKKVLR
CCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCHHEECCCHHCCCCCHHHHHHHHHHH
GELGFEGCIFSDDLNMAGAAFAGNPVERAQKALHAGCDMVLLCNNPEAAEMLLAELHWDL
HCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCC
PALGVIRLARMRGRPNPDSLVKLHENPNFVSAVEKIAGIGVRSGELPLV
CHHHHHHHHHHCCCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA