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The map label for this gene is pdxJ [H]

Identifier: 82702882

GI number: 82702882

Start: 2010386

End: 2011183

Strand: Direct

Name: pdxJ [H]

Synonym: Nmul_A1759

Alternate gene names: 82702882

Gene position: 2010386-2011183 (Clockwise)

Preceding gene: 82702880

Following gene: 82702883

Centisome position: 63.14

GC content: 57.52

Gene sequence:

>798_bases
ATGTGCGGGAGAGCAAATATCATTCAGGCAATCATTGAAAAAAAGCCGAATCAGGAAAACTCTCCCACTATCATGATCAA
ACTCGGCGTTAATATCGATCACGTCGCCACCTTGCGCCAAGCGCGCGGTACAACCTATCCCGATCCGATAGAGGCGGCAC
TCATTGCCGAATCGGCCGGAGCAGATGCCATCACCTTGCACTTGCGCGAAGACCGGCGCCACATACAGGATAGAGACGTG
GAAATCCTGCGCGGCGCCCTCAAGACCCGCATGAATCTGGAGAGCGCGGTCACGGATGAAATGATCGGATTTGCGCTGCG
CATCAAACCCCATGATATCTGCCTTGTGCCGGAACGGCGCGAAGAATTGACAACCGAAGGCGGACTCGATGTGGCACGGC
ATTTCGAGCAAGTACAACGCGCATGCCACAGGCTGGCTGAAGCCGGTATCCGGGTTTCACTCTTCGTCGATGCCGAGCCC
GCGCAGATCGATGCGTCCGTCGAGGCAGGGGCACCGGTCATCGAAATTCACACTGGACATTACGCCGATGCGCAAACGAC
GGACGAGCAGCAAGGCGAGCTGGAGCGGGTCAGGGCGGCGGTAAGCAAGGGCCTGAACCACGGACTCACGGTCAACGCCG
GGCACGGATTGCATTACCTGAATGTTCAGGCAATCGCCGCAATCCCTGGCGTGTCGGAGCTCAACATCGGGCACGCGATC
GTGGCTCGTGCATTGTTCGTGGGCTTCGAGCGGGCAGTCCGGGAAATGAAAAACCTGATGCTGGAAGCATGTAAATGA

Upstream 100 bases:

>100_bases
GCAATCAACTTGGCGATCCGCTTTTATGTACATAGTGTCTTCGCTGCACACGCTATTATAATATAGTCATTTTTTGCCCG
GTCTCTCCTGCCTCTTCCAG

Downstream 100 bases:

>100_bases
TCTATGGGATCGGAACCGATCTGGTTGAAACCTCGCGTATTACGCGCCTGCTGGAAAAATACGGAGAGCGTTTCGCCCGG
CGCCTGCTGACAGACGAGGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MCGRANIIQAIIEKKPNQENSPTIMIKLGVNIDHVATLRQARGTTYPDPIEAALIAESAGADAITLHLREDRRHIQDRDV
EILRGALKTRMNLESAVTDEMIGFALRIKPHDICLVPERREELTTEGGLDVARHFEQVQRACHRLAEAGIRVSLFVDAEP
AQIDASVEAGAPVIEIHTGHYADAQTTDEQQGELERVRAAVSKGLNHGLTVNAGHGLHYLNVQAIAAIPGVSELNIGHAI
VARALFVGFERAVREMKNLMLEACK

Sequences:

>Translated_265_residues
MCGRANIIQAIIEKKPNQENSPTIMIKLGVNIDHVATLRQARGTTYPDPIEAALIAESAGADAITLHLREDRRHIQDRDV
EILRGALKTRMNLESAVTDEMIGFALRIKPHDICLVPERREELTTEGGLDVARHFEQVQRACHRLAEAGIRVSLFVDAEP
AQIDASVEAGAPVIEIHTGHYADAQTTDEQQGELERVRAAVSKGLNHGLTVNAGHGLHYLNVQAIAAIPGVSELNIGHAI
VARALFVGFERAVREMKNLMLEACK
>Mature_265_residues
MCGRANIIQAIIEKKPNQENSPTIMIKLGVNIDHVATLRQARGTTYPDPIEAALIAESAGADAITLHLREDRRHIQDRDV
EILRGALKTRMNLESAVTDEMIGFALRIKPHDICLVPERREELTTEGGLDVARHFEQVQRACHRLAEAGIRVSLFVDAEP
AQIDASVEAGAPVIEIHTGHYADAQTTDEQQGELERVRAAVSKGLNHGLTVNAGHGLHYLNVQAIAAIPGVSELNIGHAI
VARALFVGFERAVREMKNLMLEACK

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=236, Percent_Identity=65.6779661016949, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 28999; Mature: 28999

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGRANIIQAIIEKKPNQENSPTIMIKLGVNIDHVATLRQARGTTYPDPIEAALIAESAG
CCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
ADAITLHLREDRRHIQDRDVEILRGALKTRMNLESAVTDEMIGFALRIKPHDICLVPERR
CCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEECCCHH
EELTTEGGLDVARHFEQVQRACHRLAEAGIRVSLFVDAEPAQIDASVEAGAPVIEIHTGH
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCC
YADAQTTDEQQGELERVRAAVSKGLNHGLTVNAGHGLHYLNVQAIAAIPGVSELNIGHAI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCHHHH
VARALFVGFERAVREMKNLMLEACK
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCGRANIIQAIIEKKPNQENSPTIMIKLGVNIDHVATLRQARGTTYPDPIEAALIAESAG
CCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
ADAITLHLREDRRHIQDRDVEILRGALKTRMNLESAVTDEMIGFALRIKPHDICLVPERR
CCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEECCCHH
EELTTEGGLDVARHFEQVQRACHRLAEAGIRVSLFVDAEPAQIDASVEAGAPVIEIHTGH
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCC
YADAQTTDEQQGELERVRAAVSKGLNHGLTVNAGHGLHYLNVQAIAAIPGVSELNIGHAI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCHHHH
VARALFVGFERAVREMKNLMLEACK
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA