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The map label for this gene is dgk [H]

Identifier: 82702009

GI number: 82702009

Start: 1000971

End: 1001612

Strand: Reverse

Name: dgk [H]

Synonym: Nmul_A0880

Alternate gene names: 82702009

Gene position: 1001612-1000971 (Counterclockwise)

Preceding gene: 82702010

Following gene: 82702008

Centisome position: 31.46

GC content: 53.27

Gene sequence:

>642_bases
GTGAAACTTGAGGAATATCGCCACATCGCGGTGGAAGGCCCCATCGGCGTGGGAAAAACCAGCCTGGCGCGACGAATGGC
GGAGTATGCGGGTGGACAGCTCCTGCTGGAAAAACCCGAGGAAAATCCGTTTCTCGGCAAGTTCTACGAGGATATCCGCC
GCTATGCGCTCCCTACTCAACTGTTTTTTCTGTTTCAGCGTGCCAACCAGTTGCAGGACCTGACGCAGATCGACCTGTTT
ACGAAAACGACCATAAGCGACTTCCTGCTGGATAAGGACCCGCTGTTTGCGGGACTGACGCTCAACAACGCAGAATACGA
GCTGTACCGAAAAATCTATCGCCATCTGCAACCCGAAGCTTTCACCCCCGACCTCGTGATCTATCTGCAAGCTTCACCCG
CCACGCTGGCGGAGCGGGTGAAGCGCCGCGGCAGTTCCTATGAAAAAAACATTTCCGAAACGTATTTGTGGCGATTGGCC
GACAGCTATGCGCGCTTCTTCCATCACTATGAGGATGCCCCGCTTCTGATCATCAACAGTGAGCATCTCAATTTCGTTGA
GAGCGAAGAAGATTTCGCATTACTGCTGAGGCAGGTCGAGCAAATGCGCGGCCCGAGGGAATATTTCAATTTCGAAAGAT
GA

Upstream 100 bases:

>100_bases
TGCTCGAAATTGCGTCGATCAGCAGCATACCGGGACACGACAACATAAGGGAATTGCTTGCTGCCTGTAAGGGACAGCGG
CTGGAACGCGAGCTGGACAC

Downstream 100 bases:

>100_bases
GCAAACCGGAAAACAGGAACCCGAAAATGGGTGGGATGATCTATCCGATACATGCAACCAGGAGCTGAACCATGCGTATC
ACACAAGATGTCTTTCAAAA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKLEEYRHIAVEGPIGVGKTSLARRMAEYAGGQLLLEKPEENPFLGKFYEDIRRYALPTQLFFLFQRANQLQDLTQIDLF
TKTTISDFLLDKDPLFAGLTLNNAEYELYRKIYRHLQPEAFTPDLVIYLQASPATLAERVKRRGSSYEKNISETYLWRLA
DSYARFFHHYEDAPLLIINSEHLNFVESEEDFALLLRQVEQMRGPREYFNFER

Sequences:

>Translated_213_residues
MKLEEYRHIAVEGPIGVGKTSLARRMAEYAGGQLLLEKPEENPFLGKFYEDIRRYALPTQLFFLFQRANQLQDLTQIDLF
TKTTISDFLLDKDPLFAGLTLNNAEYELYRKIYRHLQPEAFTPDLVIYLQASPATLAERVKRRGSSYEKNISETYLWRLA
DSYARFFHHYEDAPLLIINSEHLNFVESEEDFALLLRQVEQMRGPREYFNFER
>Mature_213_residues
MKLEEYRHIAVEGPIGVGKTSLARRMAEYAGGQLLLEKPEENPFLGKFYEDIRRYALPTQLFFLFQRANQLQDLTQIDLF
TKTTISDFLLDKDPLFAGLTLNNAEYELYRKIYRHLQPEAFTPDLVIYLQASPATLAERVKRRGSSYEKNISETYLWRLA
DSYARFFHHYEDAPLLIINSEHLNFVESEEDFALLLRQVEQMRGPREYFNFER

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25145; Mature: 25145

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEEYRHIAVEGPIGVGKTSLARRMAEYAGGQLLLEKPEENPFLGKFYEDIRRYALPTQ
CCCHHHCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LFFLFQRANQLQDLTQIDLFTKTTISDFLLDKDPLFAGLTLNNAEYELYRKIYRHLQPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCC
FTPDLVIYLQASPATLAERVKRRGSSYEKNISETYLWRLADSYARFFHHYEDAPLLIINS
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
EHLNFVESEEDFALLLRQVEQMRGPREYFNFER
CCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MKLEEYRHIAVEGPIGVGKTSLARRMAEYAGGQLLLEKPEENPFLGKFYEDIRRYALPTQ
CCCHHHCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LFFLFQRANQLQDLTQIDLFTKTTISDFLLDKDPLFAGLTLNNAEYELYRKIYRHLQPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCC
FTPDLVIYLQASPATLAERVKRRGSSYEKNISETYLWRLADSYARFFHHYEDAPLLIINS
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
EHLNFVESEEDFALLLRQVEQMRGPREYFNFER
CCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]