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The map label for this gene is gapA [H]

Identifier: 82701521

GI number: 82701521

Start: 425941

End: 426942

Strand: Reverse

Name: gapA [H]

Synonym: Nmul_A0387

Alternate gene names: 82701521

Gene position: 426942-425941 (Counterclockwise)

Preceding gene: 82701522

Following gene: 82701520

Centisome position: 13.41

GC content: 52.69

Gene sequence:

>1002_bases
ATGACAATCAAGGTCGGTATCAATGGATTTGGCCGGATCGGGCGAATGGTTTTCCGCGCGGCGGTACAGAATTTTCCGGA
TATTGAAGTCGTTGCCATCAATGATCTGCTTGAACCCGACTACCTCGCCTATATGCTGCAGCATGATTCCGTGCATGGCC
GCTTCAAGGGGGATGTTTCGATCGAAGACAGTACGCTCATTGTCAATGGCAAAAGAATACGGCTGACAGCGATTAAAGAC
CCGGCTGAACTGAAATGGGGAGAGGTCGGCGCTGAAGTCGTGGTTGAGTCGACCGGGCTTTTCCTCACCAAGGAAAGCTG
CCAGAAACATATTGCCGCAGGCGCAAAGAAAGTCATCATGTCTGCGCCGTCGAAAGACGATACGCCCATGTTCGTATATG
GAGTGAATAATGACTCGTATGACGGTCAGGCGATCATTTCCAATGCCTCATGCACCACGAACTGCCTGGCTCCCGTTGCA
AAGGTATTGAACGACACCTTTGGCGTCAAACGCGGCCTGATGACGACAGTTCACGCTGCTACCGCAACCCAGAAGACCGT
GGATGGTCCTTCCAACAAGGATTGGCGCGGTGGCCGGGGTATTCTGGAAAACATCATTCCCTCCTCCACCGGCGCGGCAA
AAGCCGTTGGCAAGGTTATCCCCGAACTCAATACGAAGCTTACCGGTATGGCTTTCCGCGTACCGACCTCCGATGTCTCG
GTGGTGGATCTTACGGTTGAGCTGGAAAAGGAAGCCAGCTACGAAGAAATCTGCAATGCCATGAAGAAGGCATCCGAGGG
ATCGATGAAAGGTGTGCTGGCCTATACGGACCAGAAGGTTGTTTCCACCGATTTTAGGGGCGAAAGCGCAACCTCGATTT
TCGATGCGGAAGCAGGAATGGCCCTGGACGGGAATTTTGTAAAAGTGGTTTCCTGGTACGACAACGAGTGGGGTTATTCC
AGCAAGATTCTGGAGATGGTCCGCGTTGTAGCAGGCAAGTAG

Upstream 100 bases:

>100_bases
CGGTAAACAGCGTCATTTAATTCTGACCAATTGCCAGCCGAAACGCGGAGAAAATTTTCTCCGCGTCCGAGGTTCTTTTT
TTATCCAAGGAGTGTAAAAC

Downstream 100 bases:

>100_bases
CAGAGGACCAATTCGTCACACGGGGAAGAAACTCGGAATCGTTTTTCTTCCCCCTGATCCCTGTCCTTCTCTTCAATTCA
TCATAAGGAATCCCTAGACT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTIKVGINGFGRIGRMVFRAAVQNFPDIEVVAINDLLEPDYLAYMLQHDSVHGRFKGDVSIEDSTLIVNGKRIRLTAIKD
PAELKWGEVGAEVVVESTGLFLTKESCQKHIAAGAKKVIMSAPSKDDTPMFVYGVNNDSYDGQAIISNASCTTNCLAPVA
KVLNDTFGVKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPELNTKLTGMAFRVPTSDVS
VVDLTVELEKEASYEEICNAMKKASEGSMKGVLAYTDQKVVSTDFRGESATSIFDAEAGMALDGNFVKVVSWYDNEWGYS
SKILEMVRVVAGK

Sequences:

>Translated_333_residues
MTIKVGINGFGRIGRMVFRAAVQNFPDIEVVAINDLLEPDYLAYMLQHDSVHGRFKGDVSIEDSTLIVNGKRIRLTAIKD
PAELKWGEVGAEVVVESTGLFLTKESCQKHIAAGAKKVIMSAPSKDDTPMFVYGVNNDSYDGQAIISNASCTTNCLAPVA
KVLNDTFGVKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPELNTKLTGMAFRVPTSDVS
VVDLTVELEKEASYEEICNAMKKASEGSMKGVLAYTDQKVVSTDFRGESATSIFDAEAGMALDGNFVKVVSWYDNEWGYS
SKILEMVRVVAGK
>Mature_332_residues
TIKVGINGFGRIGRMVFRAAVQNFPDIEVVAINDLLEPDYLAYMLQHDSVHGRFKGDVSIEDSTLIVNGKRIRLTAIKDP
AELKWGEVGAEVVVESTGLFLTKESCQKHIAAGAKKVIMSAPSKDDTPMFVYGVNNDSYDGQAIISNASCTTNCLAPVAK
VLNDTFGVKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPELNTKLTGMAFRVPTSDVSV
VDLTVELEKEASYEEICNAMKKASEGSMKGVLAYTDQKVVSTDFRGESATSIFDAEAGMALDGNFVKVVSWYDNEWGYSS
KILEMVRVVAGK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=60.3603603603604, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=57.1428571428571, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=72.782874617737, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=38.2978723404255, Blast_Score=249, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=61.4243323442137, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=61.4243323442137, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=60.5341246290801, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=60.5341246290801, Blast_Score=402, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=61.631419939577, Blast_Score=417, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=60.7250755287009, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=60.1208459214501, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=58.433734939759, Blast_Score=400, Evalue=1e-112,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=58.433734939759, Blast_Score=400, Evalue=1e-112,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=58.433734939759, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=58.433734939759, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=59.0769230769231, Blast_Score=390, Evalue=1e-108,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35888; Mature: 35757

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRMVFRAAVQNFPDIEVVAINDLLEPDYLAYMLQHDSVHGRFKGDVS
CEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCEE
IEDSTLIVNGKRIRLTAIKDPAELKWGEVGAEVVVESTGLFLTKESCQKHIAAGAKKVIM
ECCCEEEEECCEEEEEEECCCHHCCCCCCCCEEEEECCCEEEEHHHHHHHHHHCHHHEEE
SAPSKDDTPMFVYGVNNDSYDGQAIISNASCTTNCLAPVAKVLNDTFGVKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPELNTKLTGMAFRVPTSDVS
HHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VVDLTVELEKEASYEEICNAMKKASEGSMKGVLAYTDQKVVSTDFRGESATSIFDAEAGM
EEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCCCCCEEEECCCCE
ALDGNFVKVVSWYDNEWGYSSKILEMVRVVAGK
EECCCEEEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGINGFGRIGRMVFRAAVQNFPDIEVVAINDLLEPDYLAYMLQHDSVHGRFKGDVS
EEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCEE
IEDSTLIVNGKRIRLTAIKDPAELKWGEVGAEVVVESTGLFLTKESCQKHIAAGAKKVIM
ECCCEEEEECCEEEEEEECCCHHCCCCCCCCEEEEECCCEEEEHHHHHHHHHHCHHHEEE
SAPSKDDTPMFVYGVNNDSYDGQAIISNASCTTNCLAPVAKVLNDTFGVKRGLMTTVHAA
ECCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGKVIPELNTKLTGMAFRVPTSDVS
HHCHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VVDLTVELEKEASYEEICNAMKKASEGSMKGVLAYTDQKVVSTDFRGESATSIFDAEAGM
EEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCCCCCEEEECCCCE
ALDGNFVKVVSWYDNEWGYSSKILEMVRVVAGK
EECCCEEEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]