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The map label for this gene is fis [C]

Identifier: 82701267

GI number: 82701267

Start: 137575

End: 137817

Strand: Direct

Name: fis [C]

Synonym: Nmul_A0132

Alternate gene names: 82701267

Gene position: 137575-137817 (Clockwise)

Preceding gene: 82701266

Following gene: 82701268

Centisome position: 4.32

GC content: 49.79

Gene sequence:

>243_bases
ATGAGCATAATTAACGAAAACGATATCGCGCGGTGCGTACGCAAAACGGTCGAAGATTACTTTAACGATCTCGACGGGGA
GAAGCCGCATGCCATCCATGAAATGGTGATACGCAGCGTGGAAAAGCCCCTGATCGAACTGGTCATGGAAAGAGCCGGGG
GTAATCAAACCCGTGCCGCCGAATTGCTCGGCATCAACCGCAATACGCTGCGCAATAAAATGAAGCAGTATCAGATCAAA
TAG

Upstream 100 bases:

>100_bases
AGTCTACGGACCAGCAGCTGTCTGCGGTTAACGACTTTTTCAGTGAGCTTGCCGGCTACGGGCGGCGGTTGACCTACGTC
GAGGCTGAGGAACTGGTGGC

Downstream 100 bases:

>100_bases
ACGCTCGGGCAAAATTGTCGTTACGCGCCTGAAGGTCAGCCGCAAGCGGGCCAATTAACGGTTGTAATGCATCACGCTAC
AGACCCATCCTGATTCAATA

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MSIINENDIARCVRKTVEDYFNDLDGEKPHAIHEMVIRSVEKPLIELVMERAGGNQTRAAELLGINRNTLRNKMKQYQIK

Sequences:

>Translated_80_residues
MSIINENDIARCVRKTVEDYFNDLDGEKPHAIHEMVIRSVEKPLIELVMERAGGNQTRAAELLGINRNTLRNKMKQYQIK
>Mature_79_residues
SIINENDIARCVRKTVEDYFNDLDGEKPHAIHEMVIRSVEKPLIELVMERAGGNQTRAAELLGINRNTLRNKMKQYQIK

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=74, Percent_Identity=40.5405405405405, Blast_Score=72, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 9268; Mature: 9137

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIINENDIARCVRKTVEDYFNDLDGEKPHAIHEMVIRSVEKPLIELVMERAGGNQTRAA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ELLGINRNTLRNKMKQYQIK
HHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIINENDIARCVRKTVEDYFNDLDGEKPHAIHEMVIRSVEKPLIELVMERAGGNQTRAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ELLGINRNTLRNKMKQYQIK
HHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]