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The map label for this gene is clpX

Identifier: 78780134

GI number: 78780134

Start: 1639640

End: 1641007

Strand: Direct

Name: clpX

Synonym: PMT9312_1749

Alternate gene names: 78780134

Gene position: 1639640-1641007 (Clockwise)

Preceding gene: 78780133

Following gene: 78780135

Centisome position: 95.93

GC content: 33.48

Gene sequence:

>1368_bases
ATGGCTAAATTCGACGCCCATCTTAAATGTTCATTTTGCGGGAAATCACAAGACCAAGTAAGAAAGCTTATAGCTGGTCC
TGGGGTTTATATCTGTGATGAGTGCATAGACCTTTGTAATGAAATTCTCGATGAAGAACTACTTGATAATCAAGCGAACA
CAAACAACTCTCCGCAAGTAAAAAAGAAATTAACAAATGATAATCCAAAAAAATCTGTTCCTTTAGAATTAACCTCAATT
CCTAAGCCATTAGAAATTAAAAGTTTTCTAGATAATCAAGTTGTTGGCCAAGAATCTGCAAAAAAAATATTATCAGTAGC
CGTATATAACCACTACAAACGATTAGCATGGAAAGTTAAAGAAGAAAGTAAAAATAGCAATTCAACTGATTCACAAGCAA
CGAAATTACAAAAATCGAATATTTTACTCATCGGCCCTACTGGAAGTGGAAAAACGTTATTGGCGCAGACTTTAGCTGAG
TTTCTAGATGTTCCTTTTGCAGTTGCTGATGCAACGACTTTGACAGAAGCTGGATATGTTGGGGAAGATGTTGAAAACAT
ACTTTTAAGACTTCTACAAAAATCAGAAATGAATGTAGAACTAGCTCAAAAAGGAATTATCTATATAGATGAAATAGATA
AAATTGCAAGAAAAAGTGAGAATCCTTCAATTACTAGAGATGTCTCTGGTGAAGGAGTACAACAAGCATTATTAAAAATG
CTTGAAGGAACAATTGCTAATGTGCCACCGCAAGGCGGCAGAAAACATCCTTATCATGACTGCATCCAAATTGATACGAG
TCAAATATTATTTATTTGCGGGGGGGCTTTTATAGGTTTAGAGGATATCGTTCAAAAGCGTATGGGTAAACACTCTATAG
GATTTACCACCAATTCAGATCAAAACAACGTTGATACAAAAAAACTAGTAGAACCAAGAGATTCCTTAAAAAATTTAGAG
TTAGATGATTTAGTGAAATATGGGCTAATTCCAGAATTTATTGGAAGAATTCCCGTTTGTGCTGTATTAGATCGTCTGAC
TAAAGAAACTTTAGAATCTATTTTAACTCAACCGAGAGATGCATTAGTCAAGCAATTCAAAACGTTACTAAGTATGGATA
ATGTTGAATTGAAATTTGAGCCTGATTCTGTTGAAGCAATAGCTAATGAAGCATATAAAAGAAAAACAGGTGCAAGAGCA
TTAAGATCAATAATTGAGGAGCTTATGCTAGACGTAATGTACACTTTGCCTTCTGAAAAAAATGTAAAAGAATTCACAAT
TACAAAAAAAATGGTAGATAATTTATTCTCATCCAAAATTGTTAAACTACCTTCAGGATCAAAAAGAATCATTAAAGAGT
CTGCATAA

Upstream 100 bases:

>100_bases
GGATACTGATTTTTTAAGAATATGATGACGAATCGATATTTATAAGCAATCCTAGTGAATAGGGAATATTTAACACCTTT
CACATTAAAACTTATAATCG

Downstream 100 bases:

>100_bases
AAAGTAGAGTTTAATTTTTGCAATTTTAACCCTAATTGTTCTAATTAATGAAGAATAAATGCCTAATATACATAAGCCTT
TTCATCAAAAATATAGACCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLTNDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEESKNSNSTDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNNVDTKKLVEPRDSLKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELKFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDVMYTLPSEKNVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA

Sequences:

>Translated_455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLTNDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEESKNSNSTDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNNVDTKKLVEPRDSLKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELKFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDVMYTLPSEKNVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
>Mature_454_residues
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQVKKKLTNDNPKKSVPLELTSIP
KPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEESKNSNSTDSQATKLQKSNILLIGPTGSGKTLLAQTLAEF
LDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKML
EGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNNVDTKKLVEPRDSLKNLEL
DDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELKFEPDSVEAIANEAYKRKTGARAL
RSIIEELMLDVMYTLPSEKNVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=303, Percent_Identity=49.8349834983498, Blast_Score=289, Evalue=4e-78,
Organism=Escherichia coli, GI1786642, Length=431, Percent_Identity=55.2204176334107, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1790366, Length=217, Percent_Identity=30.4147465437788, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=294, Percent_Identity=45.9183673469388, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=294, Percent_Identity=45.9183673469388, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=38.7409200968523, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=40.7114624505929, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=37.5870069605568, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=46.3722397476341, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=46.3722397476341, Blast_Score=283, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 50568; Mature: 50437

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQV
CCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KKKLTNDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVK
HHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EESKNSNSTDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HHCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNNVDTKKLVEPRDSLKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHHCCCHHHHCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELKFEPDSVEAIANEAYKRKTGARALRSIIEELMLDVMYTLPSEK
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
CCHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNSPQV
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KKKLTNDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVK
HHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EESKNSNSTDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
HHCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNNVDTKKLVEPRDSLKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHHCCCHHHHCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELKFEPDSVEAIANEAYKRKTGARALRSIIEELMLDVMYTLPSEK
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
CCHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA