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The map label for this gene is dnaX [H]

Identifier: 78780135

GI number: 78780135

Start: 1641066

End: 1642805

Strand: Direct

Name: dnaX [H]

Synonym: PMT9312_1750

Alternate gene names: 78780135

Gene position: 1641066-1642805 (Clockwise)

Preceding gene: 78780134

Following gene: 78780138

Centisome position: 96.01

GC content: 29.02

Gene sequence:

>1740_bases
ATGCCTAATATACATAAGCCTTTTCATCAAAAATATAGACCAAGCAACCTAGATGAACTGGTAGGTCAAAATTTTATATC
CATTACTCTAAAACAAGCACTATTAACAAAAAAGATTTCTCCAGCTTATCTTTTTAATGGTCCAAGAGGCACTGGCAAAA
CATCAAGTGCGCGAATATTTGCGAAATCTTTAAACTGCCAAGCATTCGAAGAACCAACAATACATCCTTGTGGTAAGTGT
GACTTATGTAGACAAATCACAGATGGGAACGCTCTAGATATTATCGAAATTGATGCAGCATCGAATACTGGAGTAGAAAA
TATAAGAGAAATTATTGAAAGAGCTAGATTTGCACCTACTCAAGCGAGATGGAAGGTATACGTTATTGATGAATGTCATA
TGCTTTCAACAGCAGCTTCAAATGCTTTATTAAAAACTATTGAAGAACCACCCTCAAGAGTAGTATTTATTCTTGCGACA
ACAAATCCTGAGAGAGTATTAAATACAATACAAAGTAGATGTCAAAAGTTTGATTTTAGAAGAATAAGTCCTAGTGACAT
TTTTCAACATTTATCAGAAATCGCAGAAAAAGAATCGATTAAATATGAAGTTCAGGCGTTAAACATTATTGCAAAAAGAT
CTAATGGAGGTATGAGAGATGCACAAAGCCTCCTTGAACAACTTAATCTTCTTCCGGAAGGCATAACAATTAATAATATT
AAAAATCTGTTGGGAGAAGTATCAGAAATTGAATTAACAAATCTGATCAAATCATTAATTGAGAATAATCCAGAATCATT
AATTATCACCTGCAACAAATTATATGATGATGGAAACGAACCCTATCAAATCATTATTGGGTTATTAAACATAACAAGAG
ATTTACTACTTCACACTACAAATAATAAATATTCAGATCTTTATTATACTTCTGATGGATTTCAAGATGAATTGGATAAA
ATCTCAAAAACAATCAATAAATCAACAATAATTAATTGGCATAATCATCTTAGAAATATTGAATATCAACTCAAAACAAG
TGATAATCCAAGGCTTTGGCTGGAAATACATTTAACTGGCCTTTTAGATAATCACAAGATAAATAGTATTGATAATAAGC
AAGAAAAGATAAAAAGAAAGGTAATAATTAATGAAGAAAATAATTCTAATGAAATTCAAAAACCAAGTATCAAAGAGAAT
ATCAGTAGAGAGCAATTGATTTCAAAAAAAGTAGAAAAAGTAGAAAAAGTAGAAAATTTTAATGGTCTTGAAAAAGAAAA
TATGGGAAATATTTCTAAAAATAGCCAAAATAATCTTGGTTCAAATAACTTAAAAGATAAATGGGAATTAATTCTTTCTA
AATTAGAGTTGCCATCAACAAGAATGTTACTTTCACAACAAGCAGAACTTGAAAGTTTTGATTCGGAGAAAATCACAATT
GCATTAGCTCCAAACTGGGAAAATATGATAAAAAGCAGAAAAGTTATAATTGAAAATACAGTTAAAAAGATCTTTGGAGA
TCAAATAATACTTAATTTTTCAACCAAACAATTAATTCAAAGTAACAAAACAAACACTCCAGAAGTCTCCCAAAATGAAG
TAAAGAATTTGAAACTAACAAAAAAAAATGAACTAAAAACTAATTCTTCAACAAAAATATCTAACGAGGAAACTTATGAT
GATAGTTCAAAAAACTTAGCAAATTTTTTTAATGGAGAAATTATAGACCTTGATGAATAA

Upstream 100 bases:

>100_bases
CTACCTTCAGGATCAAAAAGAATCATTAAAGAGTCTGCATAAAAAGTAGAGTTTAATTTTTGCAATTTTAACCCTAATTG
TTCTAATTAATGAAGAATAA

Downstream 100 bases:

>100_bases
ATTAAACTCCAGTATGAAGAGTTTTTCGCCAAAGTATCTTTTTTGGGAAAATAGACATCTTTATTGTTACCCAGGGGATT
ACTAGAAACCAATGTGATAA

Product: DNA polymerase III, tau subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MPNIHKPFHQKYRPSNLDELVGQNFISITLKQALLTKKISPAYLFNGPRGTGKTSSARIFAKSLNCQAFEEPTIHPCGKC
DLCRQITDGNALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILAT
TNPERVLNTIQSRCQKFDFRRISPSDIFQHLSEIAEKESIKYEVQALNIIAKRSNGGMRDAQSLLEQLNLLPEGITINNI
KNLLGEVSEIELTNLIKSLIENNPESLIITCNKLYDDGNEPYQIIIGLLNITRDLLLHTTNNKYSDLYYTSDGFQDELDK
ISKTINKSTIINWHNHLRNIEYQLKTSDNPRLWLEIHLTGLLDNHKINSIDNKQEKIKRKVIINEENNSNEIQKPSIKEN
ISREQLISKKVEKVEKVENFNGLEKENMGNISKNSQNNLGSNNLKDKWELILSKLELPSTRMLLSQQAELESFDSEKITI
ALAPNWENMIKSRKVIIENTVKKIFGDQIILNFSTKQLIQSNKTNTPEVSQNEVKNLKLTKKNELKTNSSTKISNEETYD
DSSKNLANFFNGEIIDLDE

Sequences:

>Translated_579_residues
MPNIHKPFHQKYRPSNLDELVGQNFISITLKQALLTKKISPAYLFNGPRGTGKTSSARIFAKSLNCQAFEEPTIHPCGKC
DLCRQITDGNALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILAT
TNPERVLNTIQSRCQKFDFRRISPSDIFQHLSEIAEKESIKYEVQALNIIAKRSNGGMRDAQSLLEQLNLLPEGITINNI
KNLLGEVSEIELTNLIKSLIENNPESLIITCNKLYDDGNEPYQIIIGLLNITRDLLLHTTNNKYSDLYYTSDGFQDELDK
ISKTINKSTIINWHNHLRNIEYQLKTSDNPRLWLEIHLTGLLDNHKINSIDNKQEKIKRKVIINEENNSNEIQKPSIKEN
ISREQLISKKVEKVEKVENFNGLEKENMGNISKNSQNNLGSNNLKDKWELILSKLELPSTRMLLSQQAELESFDSEKITI
ALAPNWENMIKSRKVIIENTVKKIFGDQIILNFSTKQLIQSNKTNTPEVSQNEVKNLKLTKKNELKTNSSTKISNEETYD
DSSKNLANFFNGEIIDLDE
>Mature_578_residues
PNIHKPFHQKYRPSNLDELVGQNFISITLKQALLTKKISPAYLFNGPRGTGKTSSARIFAKSLNCQAFEEPTIHPCGKCD
LCRQITDGNALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATT
NPERVLNTIQSRCQKFDFRRISPSDIFQHLSEIAEKESIKYEVQALNIIAKRSNGGMRDAQSLLEQLNLLPEGITINNIK
NLLGEVSEIELTNLIKSLIENNPESLIITCNKLYDDGNEPYQIIIGLLNITRDLLLHTTNNKYSDLYYTSDGFQDELDKI
SKTINKSTIINWHNHLRNIEYQLKTSDNPRLWLEIHLTGLLDNHKINSIDNKQEKIKRKVIINEENNSNEIQKPSIKENI
SREQLISKKVEKVEKVENFNGLEKENMGNISKNSQNNLGSNNLKDKWELILSKLELPSTRMLLSQQAELESFDSEKITIA
LAPNWENMIKSRKVIIENTVKKIFGDQIILNFSTKQLIQSNKTNTPEVSQNEVKNLKLTKKNELKTNSSTKISNEETYDD
SSKNLANFFNGEIIDLDE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=290, Percent_Identity=26.8965517241379, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI31881687, Length=290, Percent_Identity=26.8965517241379, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI6677723, Length=258, Percent_Identity=25.5813953488372, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI31563534, Length=294, Percent_Identity=22.7891156462585, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI194306571, Length=251, Percent_Identity=25.8964143426295, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194306567, Length=251, Percent_Identity=25.8964143426295, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786676, Length=359, Percent_Identity=35.6545961002786, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1787119, Length=244, Percent_Identity=28.6885245901639, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=297, Percent_Identity=25.9259259259259, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541988, Length=330, Percent_Identity=23.9393939393939, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=277, Percent_Identity=26.7148014440433, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322528, Length=275, Percent_Identity=28, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324039, Length=330, Percent_Identity=26.3636363636364, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324478, Length=268, Percent_Identity=25, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17647857, Length=292, Percent_Identity=23.972602739726, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921076, Length=268, Percent_Identity=25, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859927, Length=274, Percent_Identity=28.1021897810219, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 66048; Mature: 65917

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIHKPFHQKYRPSNLDELVGQNFISITLKQALLTKKISPAYLFNGPRGTGKTSSARIF
CCCCCCCHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEE
AKSLNCQAFEEPTIHPCGKCDLCRQITDGNALDIIEIDAASNTGVENIREIIERARFAPT
EECCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATTNPERVLNTIQSRCQKFDFR
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RISPSDIFQHLSEIAEKESIKYEVQALNIIAKRSNGGMRDAQSLLEQLNLLPEGITINNI
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHH
KNLLGEVSEIELTNLIKSLIENNPESLIITCNKLYDDGNEPYQIIIGLLNITRDLLLHTT
HHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHEEEC
NNKYSDLYYTSDGFQDELDKISKTINKSTIINWHNHLRNIEYQLKTSDNPRLWLEIHLTG
CCCCCEEEEECCCCHHHHHHHHHHHCHHHEEEHHHHHCCCEEEEECCCCCEEEEEEEEEE
LLDNHKINSIDNKQEKIKRKVIINEENNSNEIQKPSIKENISREQLISKKVEKVEKVENF
EECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCC
NGLEKENMGNISKNSQNNLGSNNLKDKWELILSKLELPSTRMLLSQQAELESFDSEKITI
CCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEE
ALAPNWENMIKSRKVIIENTVKKIFGDQIILNFSTKQLIQSNKTNTPEVSQNEVKNLKLT
EECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHCCEEE
KKNELKTNSSTKISNEETYDDSSKNLANFFNGEIIDLDE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
PNIHKPFHQKYRPSNLDELVGQNFISITLKQALLTKKISPAYLFNGPRGTGKTSSARIF
CCCCCCHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEE
AKSLNCQAFEEPTIHPCGKCDLCRQITDGNALDIIEIDAASNTGVENIREIIERARFAPT
EECCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATTNPERVLNTIQSRCQKFDFR
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RISPSDIFQHLSEIAEKESIKYEVQALNIIAKRSNGGMRDAQSLLEQLNLLPEGITINNI
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHH
KNLLGEVSEIELTNLIKSLIENNPESLIITCNKLYDDGNEPYQIIIGLLNITRDLLLHTT
HHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHEEEC
NNKYSDLYYTSDGFQDELDKISKTINKSTIINWHNHLRNIEYQLKTSDNPRLWLEIHLTG
CCCCCEEEEECCCCHHHHHHHHHHHCHHHEEEHHHHHCCCEEEEECCCCCEEEEEEEEEE
LLDNHKINSIDNKQEKIKRKVIINEENNSNEIQKPSIKENISREQLISKKVEKVEKVENF
EECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCC
NGLEKENMGNISKNSQNNLGSNNLKDKWELILSKLELPSTRMLLSQQAELESFDSEKITI
CCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEE
ALAPNWENMIKSRKVIIENTVKKIFGDQIILNFSTKQLIQSNKTNTPEVSQNEVKNLKLT
EECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCCCCCHHHHHCCEEE
KKNELKTNSSTKISNEETYDDSSKNLANFFNGEIIDLDE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]