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The map label for this gene is rnhB

Identifier: 78779978

GI number: 78779978

Start: 1492848

End: 1493465

Strand: Direct

Name: rnhB

Synonym: PMT9312_1594

Alternate gene names: 78779978

Gene position: 1492848-1493465 (Clockwise)

Preceding gene: 78779977

Following gene: 78779980

Centisome position: 87.34

GC content: 30.74

Gene sequence:

>618_bases
ATGCGAGAAAAAAAAGAAGAAGATCTTCAGCAAGTATTGAATAAAGTATCCGAAGTTGGAATAGATGAAGTTGGAAGGGG
AGCAGTTTTTGGTCCAGTTTTCTCCGCTGTTGTAGTTTTAACTGAAAAAAATAAATTTATCTTGAAACAATTTGGAGTAA
AGGATAGTAAAAAATTAACTCCTAAAAAAAGAAAATTACTTTTGCCAAAAATTTTATTACTTTCTTCAGATTATGGAATT
GGGCAATCCTCAGCCAGAGAAATAGATATGCTCGGCATCAGAGTCGCAACAGAACTTTCAATGATAAGAGCTTTAAAAAA
ATTAAAAGAAAAACCATCTGAAATAATAGTTGATGGCCCTTTATTGTTAAGACCATGGAAAGGAATTCAGAAAAATATAG
TATCAGGAGACTCGAAAATTACCGCAATAGCTTCAGCAAGCATAGTTGCAAAAGTAGCTCGAGACAATCTAATGGAAAGA
TTAGAAAAAAAATACTCAGGATACTTAATATTTAAAAATAAAGGGTATGGTACCAGGGAGCATTTTTCAAATATCAAAAA
AAATGGAATAACTAATCTTCATAGGAAAAGTTTTTTAAATCAATCAGATCTTATTTAA

Upstream 100 bases:

>100_bases
AATGCAAATCCCAAAGATAAATCAAAAAAAACTAATAAAAAAAATGAAGTTATATTTATAGATAAGAAGGATGAAGTTGA
ACTTACCGATGAAATAAGCA

Downstream 100 bases:

>100_bases
TTCACACCAATCTACAAAATCTTTCACTAATTGCTGTTGAACTCTTGACTTTATACCCAACAAAATTCCGTTCAATACCG
AATGACCAGTAGATTCCAAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MREKKEEDLQQVLNKVSEVGIDEVGRGAVFGPVFSAVVVLTEKNKFILKQFGVKDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDMLGIRVATELSMIRALKKLKEKPSEIIVDGPLLLRPWKGIQKNIVSGDSKITAIASASIVAKVARDNLMER
LEKKYSGYLIFKNKGYGTREHFSNIKKNGITNLHRKSFLNQSDLI

Sequences:

>Translated_205_residues
MREKKEEDLQQVLNKVSEVGIDEVGRGAVFGPVFSAVVVLTEKNKFILKQFGVKDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDMLGIRVATELSMIRALKKLKEKPSEIIVDGPLLLRPWKGIQKNIVSGDSKITAIASASIVAKVARDNLMER
LEKKYSGYLIFKNKGYGTREHFSNIKKNGITNLHRKSFLNQSDLI
>Mature_205_residues
MREKKEEDLQQVLNKVSEVGIDEVGRGAVFGPVFSAVVVLTEKNKFILKQFGVKDSKKLTPKKRKLLLPKILLLSSDYGI
GQSSAREIDMLGIRVATELSMIRALKKLKEKPSEIIVDGPLLLRPWKGIQKNIVSGDSKITAIASASIVAKVARDNLMER
LEKKYSGYLIFKNKGYGTREHFSNIKKNGITNLHRKSFLNQSDLI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=37.3626373626374, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PROM9 (Q318P1)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_398090.1
- ProteinModelPortal:   Q318P1
- SMR:   Q318P1
- STRING:   Q318P1
- GeneID:   3766412
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1594
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK13925
- BioCyc:   PMAR74546:PMT9312_1594-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22979; Mature: 22979

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKKEEDLQQVLNKVSEVGIDEVGRGAVFGPVFSAVVVLTEKNKFILKQFGVKDSKKLT
CCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHEECCCHHHHHHHCCCCCCCCC
PKKRKLLLPKILLLSSDYGIGQSSAREIDMLGIRVATELSMIRALKKLKEKPSEIIVDGP
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
LLLRPWKGIQKNIVSGDSKITAIASASIVAKVARDNLMERLEKKYSGYLIFKNKGYGTRE
EEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHH
HFSNIKKNGITNLHRKSFLNQSDLI
HHHHHHHCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MREKKEEDLQQVLNKVSEVGIDEVGRGAVFGPVFSAVVVLTEKNKFILKQFGVKDSKKLT
CCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHEECCCHHHHHHHCCCCCCCCC
PKKRKLLLPKILLLSSDYGIGQSSAREIDMLGIRVATELSMIRALKKLKEKPSEIIVDGP
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
LLLRPWKGIQKNIVSGDSKITAIASASIVAKVARDNLMERLEKKYSGYLIFKNKGYGTRE
EEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHH
HFSNIKKNGITNLHRKSFLNQSDLI
HHHHHHHCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA