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The map label for this gene is pheA [H]

Identifier: 78779980

GI number: 78779980

Start: 1494022

End: 1494867

Strand: Direct

Name: pheA [H]

Synonym: PMT9312_1596

Alternate gene names: 78779980

Gene position: 1494022-1494867 (Clockwise)

Preceding gene: 78779978

Following gene: 78779988

Centisome position: 87.41

GC content: 32.51

Gene sequence:

>846_bases
ATGAGCAAACAAGTTGCATATTTAGGTCCTCAAGGGACATACGCAGAAAAAGCAGCTCATATATTATCAAAGCTTGCCAA
TTTTCAGACACCTATATTTGTACCATGTAACGGACTACATTCGGTTATAAAATCATTAGCCTACAAAAATTGTGATGCTG
CTGTAGTTCCTATTGAAAATTCTGTAGAAGGTGGAGTGACAGCCACTCTAGATGCCCTCTGGAAATTTCCTGATATTTTT
ATCAATAAAGCAATTGTTTTACCCATCAAACATGCATTAATTAGTGATGGAGAACTTTCAAAGATTTCAGAAGTATTATC
TCATCCTCAAGCATTAGCTCAATGTTCAGAATGGTTATCTGAAAATCTTCCAAATGCTATCCCTCTTCCAACAAATTCAA
CATCAGAAGCTGTGAATATGGTAAAGGGAAGTCAATTTAGAGCAGCTATCGGTTCAAAATCATTAATTCAAATTGAAGGG
CTTAAAGAATTAGCCTTCCCTATTAATGATGTTCCAGGTAATTGCACTAGATTTGTCTTATTGAGCAAAGAATCAAATTC
TAATTCGCCTAATCTTGCCAGTTTTGCTTTCTCATTAATCTCCAACAAACCAGGTGCTTTACTTAAGGCTATAAATTATA
TTGCTGATTTTGGCTTTAATATGAGTAAAATAGAGTCTAGACCTTCTAAAAGAGAGTTAGGGGAATATATTATATATGTT
GATTTAGAAATCAATAATCAAAATAATATTGAAAACTTTCTTGAATTAAAAAATCATCTCAAACCCCTATGCAATAACTT
TGTAGATTTTGGAAATTATTTTTCTGAGAATATTGAGTTAGATTAA

Upstream 100 bases:

>100_bases
TGTTACGGAAAGCTTTAGTTTTTGTTTTGCATCAAAAGACAATAGCATTTTCTATATTCCTCCAATGCTTACTTGATCTT
TTTTTTTCTTACTATTAATC

Downstream 100 bases:

>100_bases
TTTATCCTCTACATTTATAAACTCCAAACTCCATTAAACCTTTTCTAAATGCCCAATTCATAAGAAGTATTGTCGGGATC
TCTCTTATTGACTTAACTAT

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSKQVAYLGPQGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYKNCDAAVVPIENSVEGGVTATLDALWKFPDIF
INKAIVLPIKHALISDGELSKISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSQFRAAIGSKSLIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNSPNLASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYV
DLEINNQNNIENFLELKNHLKPLCNNFVDFGNYFSENIELD

Sequences:

>Translated_281_residues
MSKQVAYLGPQGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYKNCDAAVVPIENSVEGGVTATLDALWKFPDIF
INKAIVLPIKHALISDGELSKISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSQFRAAIGSKSLIQIEG
LKELAFPINDVPGNCTRFVLLSKESNSNSPNLASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYV
DLEINNQNNIENFLELKNHLKPLCNNFVDFGNYFSENIELD
>Mature_280_residues
SKQVAYLGPQGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYKNCDAAVVPIENSVEGGVTATLDALWKFPDIFI
NKAIVLPIKHALISDGELSKISEVLSHPQALAQCSEWLSENLPNAIPLPTNSTSEAVNMVKGSQFRAAIGSKSLIQIEGL
KELAFPINDVPGNCTRFVLLSKESNSNSPNLASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYVD
LEINNQNNIENFLELKNHLKPLCNNFVDFGNYFSENIELD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=286, Percent_Identity=30.4195804195804, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324013, Length=309, Percent_Identity=27.831715210356, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 30819; Mature: 30687

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQVAYLGPQGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYKNCDAAVVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCC
SVEGGVTATLDALWKFPDIFINKAIVLPIKHALISDGELSKISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHCHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSQFRAAIGSKSLIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNSPNLASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYV
EECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DLEINNQNNIENFLELKNHLKPLCNNFVDFGNYFSENIELD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKQVAYLGPQGTYAEKAAHILSKLANFQTPIFVPCNGLHSVIKSLAYKNCDAAVVPIEN
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCC
SVEGGVTATLDALWKFPDIFINKAIVLPIKHALISDGELSKISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHCHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPNAIPLPTNSTSEAVNMVKGSQFRAAIGSKSLIQIEGLKELAFPINDVPGNCTRFVL
HCCCCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCEEEEE
LSKESNSNSPNLASFAFSLISNKPGALLKAINYIADFGFNMSKIESRPSKRELGEYIIYV
EECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DLEINNQNNIENFLELKNHLKPLCNNFVDFGNYFSENIELD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]