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The map label for this gene is umuD [H]

Identifier: 78779247

GI number: 78779247

Start: 799327

End: 799743

Strand: Reverse

Name: umuD [H]

Synonym: PMT9312_0863

Alternate gene names: 78779247

Gene position: 799743-799327 (Counterclockwise)

Preceding gene: 78779248

Following gene: 78779246

Centisome position: 46.79

GC content: 28.3

Gene sequence:

>417_bases
TTGGATTCCTTTGATTCAACCACTAAAAAATTCAAAATCCCCTTATTAAATGATTCGGTATCTGCAGGATTTCCTTCTCC
TGCAGATGACTATACAGAAGAGAATATTGATTTAAATGAACATTTAATATCTAATCCGTTTAGCACTTTTTTTCTTAGAG
TTAGAGGTGACTCAATGATAAATGCAGGAATTAAAGATAAAGATTTAATAATAGTAGACAAAAGTTTAACAGCCAAGCCA
GGGAATATTATCATTGCAATGATAGACGGGGAATTTACAATAAAAAGATTATCTATAAAAAATGATGAATTATATTTAAA
AGCAGAAAATCATAATTATCCTGATTTTAGATTTAAAAACCATATTGATGTACAGATATGGGGCGTTGTTATTTATTCAA
TACATAGCTATTTATGA

Upstream 100 bases:

>100_bases
TTGATTTGATTTTATCTAAAATTAATCTATAAAACATTAACAACCAACTATTTTTTTTGATTTTTTATTATATAGTACAT
ATATACTATTAATTCAAGTT

Downstream 100 bases:

>100_bases
GAATTTCAAGCATTGATGCTATAGCTCTTATAGATGCTAATAATTTTTATGCGTCATGTGAACAAACTATTAATCCTCAT
TTGAGAAATAAACCAGTAGT

Product: SOS mutagenesis protein UmuD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MDSFDSTTKKFKIPLLNDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVRGDSMINAGIKDKDLIIVDKSLTAKP
GNIIIAMIDGEFTIKRLSIKNDELYLKAENHNYPDFRFKNHIDVQIWGVVIYSIHSYL

Sequences:

>Translated_138_residues
MDSFDSTTKKFKIPLLNDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVRGDSMINAGIKDKDLIIVDKSLTAKP
GNIIIAMIDGEFTIKRLSIKNDELYLKAENHNYPDFRFKNHIDVQIWGVVIYSIHSYL
>Mature_138_residues
MDSFDSTTKKFKIPLLNDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVRGDSMINAGIKDKDLIIVDKSLTAKP
GNIIIAMIDGEFTIKRLSIKNDELYLKAENHNYPDFRFKNHIDVQIWGVVIYSIHSYL

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=123, Percent_Identity=44.7154471544715, Blast_Score=115, Evalue=8e-28,
Organism=Escherichia coli, GI1790476, Length=101, Percent_Identity=35.6435643564356, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15743; Mature: 15743

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFDSTTKKFKIPLLNDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVRGDSMI
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCEE
NAGIKDKDLIIVDKSLTAKPGNIIIAMIDGEFTIKRLSIKNDELYLKAENHNYPDFRFKN
ECCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCCCEECC
HIDVQIWGVVIYSIHSYL
CCCEEEHHEEEEEHHHCC
>Mature Secondary Structure
MDSFDSTTKKFKIPLLNDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVRGDSMI
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCEE
NAGIKDKDLIIVDKSLTAKPGNIIIAMIDGEFTIKRLSIKNDELYLKAENHNYPDFRFKN
ECCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCCCEECC
HIDVQIWGVVIYSIHSYL
CCCEEEHHEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]