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The map label for this gene is ubiE [H]

Identifier: 78778815

GI number: 78778815

Start: 405922

End: 406623

Strand: Direct

Name: ubiE [H]

Synonym: PMT9312_0430

Alternate gene names: 78778815

Gene position: 405922-406623 (Clockwise)

Preceding gene: 78778814

Following gene: 78778817

Centisome position: 23.75

GC content: 27.92

Gene sequence:

>702_bases
ATGAAATTCACAAAAACTATCGAAGTCAAAAATATATTTAATAAAATTTCTTATAAATATGACTTTTTAAATAATCTATT
AAGTTTTGGGCTGCACAGATTATGGAAAAGGAAATTAGTTGATTTATTGGAACCTTTAAATGGTGAAGATTGGGCAGATT
TATGCTGTGGAACTGGAGATTTAGCATTCTTAATTTCTGAGAGAGTTAGTCCAAGGGGTTCAATTACTGGGATTGACAGT
GCAGAGGATATCTTAAATATTGCAAAAAAAAAATCAGAGCTAAAAAAAAATAAATTTATTAAGTGGGAAATTAAAGATGT
ATTAGAAATTAATGATTATTCAAAAAATTTTGATGGAATTTGCATGTCATATGGACTTAGAAACTTGAATAATGTTGAAG
GAGGAATAAAAAAAGTTTTTGATCTTTTGAAGGATAAGGGAAGGGCAGGATTTTTGGATTTTAATCACTCAACAAGAAAT
TCTTTATCCAATATTTTTCAGAAAATTTATTTGAGATTAATTGTAGTAACCATTTCGCGGCTTTTTAATTTAGGTCCTGA
GTACGCATATATTGAAAAAAGTATTAGTAATTTTCCAAAGAAAAATGTGCTTATAAATATTGCTAAGGAAGTTGGATTTA
AAAAAGCTGAATATAGGACTATTTTGGGGGGGCAAATGGGGATACTAATTTTAACTAAATAA

Upstream 100 bases:

>100_bases
TTAAGAGAAATAAAGACTTTCCTCCTCGAAAGAAAACTTCCAATTAGACCATATGAATAAAAAATTTAATACCAAAAAGA
AATAAGTTAAAAATTTAAAA

Downstream 100 bases:

>100_bases
AGAATTTAGTTTTTAATTATTTTTTCTCCAACAAAAAGAACACTTTCCCCATCTTTTGATTTCGCCCTCAGGAGTAGGGG
AATTACAAAGAGTACAAATG

Product: demethylmenaquinone methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVDLLEPLNGEDWADLCCGTGDLAFLISERVSPRGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEGGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNVLINIAKEVGFKKAEYRTILGGQMGILILTK

Sequences:

>Translated_233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVDLLEPLNGEDWADLCCGTGDLAFLISERVSPRGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEGGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNVLINIAKEVGFKKAEYRTILGGQMGILILTK
>Mature_233_residues
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVDLLEPLNGEDWADLCCGTGDLAFLISERVSPRGSITGIDS
AEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGICMSYGLRNLNNVEGGIKKVFDLLKDKGRAGFLDFNHSTRN
SLSNIFQKIYLRLIVVTISRLFNLGPEYAYIEKSISNFPKKNVLINIAKEVGFKKAEYRTILGGQMGILILTK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=224, Percent_Identity=27.6785714285714, Blast_Score=103, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17557039, Length=228, Percent_Identity=29.8245614035088, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323526, Length=249, Percent_Identity=25.3012048192771, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24641702, Length=238, Percent_Identity=23.5294117647059, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 26701; Mature: 26701

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01183 UBIE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVDLLEPLNGEDWADLCCGTGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH
LAFLISERVSPRGSITGIDSAEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHCCCCCCCHH
CMSYGLRNLNNVEGGIKKVFDLLKDKGRAGFLDFNHSTRNSLSNIFQKIYLRLIVVTISR
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLGPEYAYIEKSISNFPKKNVLINIAKEVGFKKAEYRTILGGQMGILILTK
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MKFTKTIEVKNIFNKISYKYDFLNNLLSFGLHRLWKRKLVDLLEPLNGEDWADLCCGTGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH
LAFLISERVSPRGSITGIDSAEDILNIAKKKSELKKNKFIKWEIKDVLEINDYSKNFDGI
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHCCCCCCCHH
CMSYGLRNLNNVEGGIKKVFDLLKDKGRAGFLDFNHSTRNSLSNIFQKIYLRLIVVTISR
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
LFNLGPEYAYIEKSISNFPKKNVLINIAKEVGFKKAEYRTILGGQMGILILTK
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]