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The map label for this gene is aroQ

Identifier: 78484790

GI number: 78484790

Start: 497702

End: 498136

Strand: Reverse

Name: aroQ

Synonym: Tcr_0445

Alternate gene names: 78484790

Gene position: 498136-497702 (Counterclockwise)

Preceding gene: 78484791

Following gene: 78484789

Centisome position: 20.52

GC content: 45.98

Gene sequence:

>435_bases
ATGGCAAACATTCTCGTAATCAACGGCCCCAATCTCAATATGCTAGGCAAAAGAGAACCGGAACATTATGGTCGCCAAAC
CTTGGGCGACATTATCGAGGAACTCGAAACACTTGCAGATGATTATGAAGTGCGTTTATACAACTTCCAGAGCAATGCCG
AGCACGAAATAGTGGAACGCATCCAGACCGCGATTGACGATATTGATTTCATTATCATCAACCCTGCGGCGTTCACACAC
ACCAGTGTCGCGATACGAGACGCCTTATCGACCGTCAAGATCCCTTTTATTGAAGTGCATTTGTCTAACATTCATAAAAG
AGAAGCTTTTCGAACCCATTCATATTTTTCCGATTTGGCTGAAGGCGTTATTGCCGGGCTAGGTCCAATCGGCTACCAGC
TCGCACTGGCCGCCGCAGTTGAAAAACTGAAATAA

Upstream 100 bases:

>100_bases
CGACTTTTTTACAACTTTCTATATCGTTAAACCTAACTTTCAGGTATAATTTTCAACAATTTAATGATTAGCTCCGCTGA
GATGAATCAAGGATACTTTC

Downstream 100 bases:

>100_bases
AAAAATACATTTAAATAACGACTATTTAAGAGGAATAGAGAACATGGATATTCGTTCAATTCGTAAATTGATTGAAATTG
TAGAACAGTCTGACGTTGCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MANILVINGPNLNMLGKREPEHYGRQTLGDIIEELETLADDYEVRLYNFQSNAEHEIVERIQTAIDDIDFIIINPAAFTH
TSVAIRDALSTVKIPFIEVHLSNIHKREAFRTHSYFSDLAEGVIAGLGPIGYQLALAAAVEKLK

Sequences:

>Translated_144_residues
MANILVINGPNLNMLGKREPEHYGRQTLGDIIEELETLADDYEVRLYNFQSNAEHEIVERIQTAIDDIDFIIINPAAFTH
TSVAIRDALSTVKIPFIEVHLSNIHKREAFRTHSYFSDLAEGVIAGLGPIGYQLALAAAVEKLK
>Mature_143_residues
ANILVINGPNLNMLGKREPEHYGRQTLGDIIEELETLADDYEVRLYNFQSNAEHEIVERIQTAIDDIDFIIINPAAFTHT
SVAIRDALSTVKIPFIEVHLSNIHKREAFRTHSYFSDLAEGVIAGLGPIGYQLALAAAVEKLK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_THICR (Q31II2)

Other databases:

- EMBL:   CP000109
- RefSeq:   YP_390715.1
- HSSP:   Q48255
- ProteinModelPortal:   Q31II2
- SMR:   Q31II2
- STRING:   Q31II2
- GeneID:   3761472
- GenomeReviews:   CP000109_GR
- KEGG:   tcx:Tcr_0445
- NMPDR:   fig|317025.3.peg.623
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   TCRU317025:TCR_0445-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16101; Mature: 15969

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILVINGPNLNMLGKREPEHYGRQTLGDIIEELETLADDYEVRLYNFQSNAEHEIVER
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
IQTAIDDIDFIIINPAAFTHTSVAIRDALSTVKIPFIEVHLSNIHKREAFRTHSYFSDLA
HHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHH
EGVIAGLGPIGYQLALAAAVEKLK
HHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANILVINGPNLNMLGKREPEHYGRQTLGDIIEELETLADDYEVRLYNFQSNAEHEIVER
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
IQTAIDDIDFIIINPAAFTHTSVAIRDALSTVKIPFIEVHLSNIHKREAFRTHSYFSDLA
HHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHH
EGVIAGLGPIGYQLALAAAVEKLK
HHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA