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The map label for this gene is ccpA [H]

Identifier: 78358693

GI number: 78358693

Start: 3616835

End: 3617899

Strand: Direct

Name: ccpA [H]

Synonym: Dde_3654

Alternate gene names: 78358693

Gene position: 3616835-3617899 (Clockwise)

Preceding gene: 78358692

Following gene: 78358694

Centisome position: 96.96

GC content: 62.25

Gene sequence:

>1065_bases
ATGAGGTCAAACTGCAAACGTTTGCAGCAACTGCGGCACCCGCCGCAAAACGGACAGCGCATGCGCCAGTACACCATTAA
AGACATCGCCAGAGAACTGGGGGTTTCACCCTCGACGGTGTCGCGTGCGCTCAGCGGACACCCCGGCATCAGCGCCCGGA
CCCGCAGCAGGGTTCAGGAACTGGCCCGCCTGCACAACTACCAGCCCAACCTGCTCGCTAAAAGTCTGCAGCAGAAGCAT
TCCAGCACCATCGGCGTCATTGTGCCGGAGATCCGCCACGACTTTTTCGCCGCCACCATCAGCGGCATCGAAGAGGTGGC
CTACACGGCAGGATACGCCATCATGGTCTGCCAGAGCCATGAAACACTCGACCGCGAAACAACCAACATAGCCGCACTGC
TGGGACAGCGCATAGCGGGCCTGCTGCTTTCCGTCTCGTGCCGCACGCACGACGCACGGCATCTTGCTCCGGTGCTGCGC
AGCCGCACGCCTCTGGTGGTTTTCGACAGAGTGCCCGAAGGATTTGCAGGCAGCACAGTCACCACCGACGACGAGCAGGG
AGCCTGTGACATCACAGCGCTGCTGCTGCAAAAAGGCTACCGGCGCATAGCCCACATAGGAGGCCCCCCGCATCTGGCCA
TAAGCCGCCGACGGTACGCAGGGTATACAAAAGCCCTTGCCGCGGCGGGAATACCGCAGTTTTCCGGATACCATATTCAG
GGCGGCTTTGACGAAGAAGACGGCAGACGCGGCGCCATGCAGCTTTTTGACCTTGCGCAGCCGCCTGACGCCATCATGGC
CGTCACCGACCCTGTGGCACTGGGAGTGTACAGCGCCGCGCGGCAGCGGGGTTTGCGCATACCGCAGGATATAGCGGTCA
CCGGATTCAGCGGCAACCCCGTGGGCGAACTGATCACCCCGCGCCTGACAACAGTATACCAGCCAGCCTTTGAAATGGGC
AGACGCGCCGCCGGCCTGCTGCTGGAACAGATACGCGGCACCGCGGCACAAAGCACAGCAACCGTGTCATTGCCCACGCG
TGTGGTTGTGCGCGAATCGGCGTAG

Upstream 100 bases:

>100_bases
CATCCCGCTGGATATCCGCGGCAGCGGCCTGCACCGGCTGCTCCCGTAAGTCAGCTCCGCAGGCAAAAAAAGCCGTGCCG
CTTTTGACAAAACCATGTAA

Downstream 100 bases:

>100_bases
AGGCAGACATGAGCAGCACGCAGGATACATGTTTTACGCACCTGTCAGGTGCGCATACTGTCAGACCGCAACCCTGCGCA
ACAATACCGCACTGTTCCTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MRSNCKRLQQLRHPPQNGQRMRQYTIKDIARELGVSPSTVSRALSGHPGISARTRSRVQELARLHNYQPNLLAKSLQQKH
SSTIGVIVPEIRHDFFAATISGIEEVAYTAGYAIMVCQSHETLDRETTNIAALLGQRIAGLLLSVSCRTHDARHLAPVLR
SRTPLVVFDRVPEGFAGSTVTTDDEQGACDITALLLQKGYRRIAHIGGPPHLAISRRRYAGYTKALAAAGIPQFSGYHIQ
GGFDEEDGRRGAMQLFDLAQPPDAIMAVTDPVALGVYSAARQRGLRIPQDIAVTGFSGNPVGELITPRLTTVYQPAFEMG
RRAAGLLLEQIRGTAAQSTATVSLPTRVVVRESA

Sequences:

>Translated_354_residues
MRSNCKRLQQLRHPPQNGQRMRQYTIKDIARELGVSPSTVSRALSGHPGISARTRSRVQELARLHNYQPNLLAKSLQQKH
SSTIGVIVPEIRHDFFAATISGIEEVAYTAGYAIMVCQSHETLDRETTNIAALLGQRIAGLLLSVSCRTHDARHLAPVLR
SRTPLVVFDRVPEGFAGSTVTTDDEQGACDITALLLQKGYRRIAHIGGPPHLAISRRRYAGYTKALAAAGIPQFSGYHIQ
GGFDEEDGRRGAMQLFDLAQPPDAIMAVTDPVALGVYSAARQRGLRIPQDIAVTGFSGNPVGELITPRLTTVYQPAFEMG
RRAAGLLLEQIRGTAAQSTATVSLPTRVVVRESA
>Mature_354_residues
MRSNCKRLQQLRHPPQNGQRMRQYTIKDIARELGVSPSTVSRALSGHPGISARTRSRVQELARLHNYQPNLLAKSLQQKH
SSTIGVIVPEIRHDFFAATISGIEEVAYTAGYAIMVCQSHETLDRETTNIAALLGQRIAGLLLSVSCRTHDARHLAPVLR
SRTPLVVFDRVPEGFAGSTVTTDDEQGACDITALLLQKGYRRIAHIGGPPHLAISRRRYAGYTKALAAAGIPQFSGYHIQ
GGFDEEDGRRGAMQLFDLAQPPDAIMAVTDPVALGVYSAARQRGLRIPQDIAVTGFSGNPVGELITPRLTTVYQPAFEMG
RRAAGLLLEQIRGTAAQSTATVSLPTRVVVRESA

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=309, Percent_Identity=35.5987055016181, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=33.0097087378641, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787948, Length=310, Percent_Identity=30, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=29.8305084745763, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788474, Length=324, Percent_Identity=29.320987654321, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787580, Length=325, Percent_Identity=28.6153846153846, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790715, Length=327, Percent_Identity=26.9113149847095, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1789068, Length=312, Percent_Identity=26.6025641025641, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=26.625386996904, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=26.6467065868263, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789456, Length=338, Percent_Identity=27.2189349112426, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=24.2603550295858, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786268, Length=310, Percent_Identity=22.9032258064516, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=25.6329113924051, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38502; Mature: 38502

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSNCKRLQQLRHPPQNGQRMRQYTIKDIARELGVSPSTVSRALSGHPGISARTRSRVQE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHH
LARLHNYQPNLLAKSLQQKHSSTIGVIVPEIRHDFFAATISGIEEVAYTAGYAIMVCQSH
HHHHHCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ETLDRETTNIAALLGQRIAGLLLSVSCRTHDARHLAPVLRSRTPLVVFDRVPEGFAGSTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCC
TTDDEQGACDITALLLQKGYRRIAHIGGPPHLAISRRRYAGYTKALAAAGIPQFSGYHIQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCEEEC
GGFDEEDGRRGAMQLFDLAQPPDAIMAVTDPVALGVYSAARQRGLRIPQDIAVTGFSGNP
CCCCCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
VGELITPRLTTVYQPAFEMGRRAAGLLLEQIRGTAAQSTATVSLPTRVVVRESA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEECCEEEEEECCC
>Mature Secondary Structure
MRSNCKRLQQLRHPPQNGQRMRQYTIKDIARELGVSPSTVSRALSGHPGISARTRSRVQE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHH
LARLHNYQPNLLAKSLQQKHSSTIGVIVPEIRHDFFAATISGIEEVAYTAGYAIMVCQSH
HHHHHCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
ETLDRETTNIAALLGQRIAGLLLSVSCRTHDARHLAPVLRSRTPLVVFDRVPEGFAGSTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCC
TTDDEQGACDITALLLQKGYRRIAHIGGPPHLAISRRRYAGYTKALAAAGIPQFSGYHIQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCEEEC
GGFDEEDGRRGAMQLFDLAQPPDAIMAVTDPVALGVYSAARQRGLRIPQDIAVTGFSGNP
CCCCCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
VGELITPRLTTVYQPAFEMGRRAAGLLLEQIRGTAAQSTATVSLPTRVVVRESA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]