| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome, complete genome. |
|---|---|
| Accession | NC_007519 |
| Length | 3,730,232 |
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The map label for this gene is galK [H]
Identifier: 78358692
GI number: 78358692
Start: 3615479
End: 3616783
Strand: Direct
Name: galK [H]
Synonym: Dde_3653
Alternate gene names: 78358692
Gene position: 3615479-3616783 (Clockwise)
Preceding gene: 78358691
Following gene: 78358693
Centisome position: 96.92
GC content: 65.59
Gene sequence:
>1305_bases ATGATACCCGCGCTGCATACGCAGCAGGAAATGCTGAACGCCCTGCATAGGGGGGCGCTGGACGCGGGGCTGCGCGCCCT GTACGCGCCGGACAGCGACAGCGGGCACACAGCCGCTGCGGCACGCATCCGGCTGGAAAACCTGCTGCATGAACATCTGC ACCGCTACGGCCCGCGGCCTGTGGGTATTTTCAGCGCGCCCGGCCGTACGGAGCTGGCAGGCAACCATACCGACCACAAC AAGGGTGTGGTGGTGGCGGCAGCAGTCACACTGGACTGTCTGGCCGTGGCTTCTGCCCGCGCCGACCTGCGCGTGCATCT GGTTTCCGCCGGATTTGCCCGTCCGGTGGACCTGACACTGGATGACCTGCAGCCGCGCGCGGACGAAAAAGAAACCCCCG CGGCCATCGTCAGAGGCATGGCTGCCGGCATACACGGCCTGATGCCCCTCTGCGGATTCGATGCCTGTGTGCACAGTACG GTTCCCGTGGGTGCGGGACTCAGCTCCTCCGCAGCATTCGAGGTGCTCTGCGGCCGCATTTTTTCAGGCTGGCATTCCGG TTACGTCCTCACTCAGCAAACGCTGGCGGCACTGGCCCATACCGCAGAATCCCGTTATTTCGGCAAGCCATGCGGCGAAA TGGATCAACTGGCCTGTGCGGGCAGCGGAGCTTCGGTCATCCGCTTCGGCATGCCGCAGGGCAAAAACGTTGAAGCCGTG CCCGTCAATATTGCGGAAGCCGGCTATCAGCTTGCGGTTGTAAACACGGGGGGCAGCCACGCCGACCTGACGGCGGAATA CGCCGCCATACCCGCAGAGATGCGCCGCGCCGCGGCCGTACTGGGCAAGCAGCAGGCCCACGGCATCACCGCCGCAGAGG TGCTGCGCCACGCCGCAGCCATCCGCAATGCGGCCGGAGACCGGGCCCTGCTGCGGCTGCTTCATTTTGCCGAAGAGACA CAGCGTGCCGAAGCCGTGGCACAGGCGCTGCGTCACAACCGCACGCAGGAATTGCTGCGGCTGGTCAATGCCAGCGGCGA TTCTTCGTGGCGGCTGCTGCAAAACTGCTACCCCGCCGGTGCGTCCGCCCAGCCCCTGCCCGTGGCGCTGGAAACGACCC GCCTGCAACTGGACGGGCAAGGGGCATGGCGTGTGCACGGCGGAGGATTTGCCGGTACCATACAGGTCTATGTGCCGCAG CGGCTCATGGCCGGCTACACAAAGTGCATGGAACAGCTTTTCGGCGACGGGTGTGTCATCCCGCTGGATATCCGCGGCAG CGGCCTGCACCGGCTGCTCCCGTAA
Upstream 100 bases:
>100_bases TGGGCAGCCCGCAGCGCGACCTGACTGCAGAGAGCGCGGCGGACAAGCTGCGCGCCCTTTCCGACGTGCATTACACGGAC CTGCGGCAGGGGTCTGCAAC
Downstream 100 bases:
>100_bases GTCAGCTCCGCAGGCAAAAAAAGCCGTGCCGCTTTTGACAAAACCATGTAAATGAGGTCAAACTGCAAACGTTTGCAGCA ACTGCGGCACCCGCCGCAAA
Product: galactokinase
Products: NA
Alternate protein names: Galactose kinase [H]
Number of amino acids: Translated: 434; Mature: 434
Protein sequence:
>434_residues MIPALHTQQEMLNALHRGALDAGLRALYAPDSDSGHTAAAARIRLENLLHEHLHRYGPRPVGIFSAPGRTELAGNHTDHN KGVVVAAAVTLDCLAVASARADLRVHLVSAGFARPVDLTLDDLQPRADEKETPAAIVRGMAAGIHGLMPLCGFDACVHST VPVGAGLSSSAAFEVLCGRIFSGWHSGYVLTQQTLAALAHTAESRYFGKPCGEMDQLACAGSGASVIRFGMPQGKNVEAV PVNIAEAGYQLAVVNTGGSHADLTAEYAAIPAEMRRAAAVLGKQQAHGITAAEVLRHAAAIRNAAGDRALLRLLHFAEET QRAEAVAQALRHNRTQELLRLVNASGDSSWRLLQNCYPAGASAQPLPVALETTRLQLDGQGAWRVHGGGFAGTIQVYVPQ RLMAGYTKCMEQLFGDGCVIPLDIRGSGLHRLLP
Sequences:
>Translated_434_residues MIPALHTQQEMLNALHRGALDAGLRALYAPDSDSGHTAAAARIRLENLLHEHLHRYGPRPVGIFSAPGRTELAGNHTDHN KGVVVAAAVTLDCLAVASARADLRVHLVSAGFARPVDLTLDDLQPRADEKETPAAIVRGMAAGIHGLMPLCGFDACVHST VPVGAGLSSSAAFEVLCGRIFSGWHSGYVLTQQTLAALAHTAESRYFGKPCGEMDQLACAGSGASVIRFGMPQGKNVEAV PVNIAEAGYQLAVVNTGGSHADLTAEYAAIPAEMRRAAAVLGKQQAHGITAAEVLRHAAAIRNAAGDRALLRLLHFAEET QRAEAVAQALRHNRTQELLRLVNASGDSSWRLLQNCYPAGASAQPLPVALETTRLQLDGQGAWRVHGGGFAGTIQVYVPQ RLMAGYTKCMEQLFGDGCVIPLDIRGSGLHRLLP >Mature_434_residues MIPALHTQQEMLNALHRGALDAGLRALYAPDSDSGHTAAAARIRLENLLHEHLHRYGPRPVGIFSAPGRTELAGNHTDHN KGVVVAAAVTLDCLAVASARADLRVHLVSAGFARPVDLTLDDLQPRADEKETPAAIVRGMAAGIHGLMPLCGFDACVHST VPVGAGLSSSAAFEVLCGRIFSGWHSGYVLTQQTLAALAHTAESRYFGKPCGEMDQLACAGSGASVIRFGMPQGKNVEAV PVNIAEAGYQLAVVNTGGSHADLTAEYAAIPAEMRRAAAVLGKQQAHGITAAEVLRHAAAIRNAAGDRALLRLLHFAEET QRAEAVAQALRHNRTQELLRLVNASGDSSWRLLQNCYPAGASAQPLPVALETTRLQLDGQGAWRVHGGGFAGTIQVYVPQ RLMAGYTKCMEQLFGDGCVIPLDIRGSGLHRLLP
Specific function: Galactose metabolism; first step. [C]
COG id: COG0153
COG function: function code G; Galactokinase
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the GHMP kinase family. GalK subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503895, Length=354, Percent_Identity=29.9435028248588, Blast_Score=98, Evalue=2e-20, Organism=Escherichia coli, GI1786972, Length=343, Percent_Identity=24.4897959183673, Blast_Score=84, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000705 - InterPro: IPR022963 - InterPro: IPR019741 - InterPro: IPR019539 - InterPro: IPR006204 - InterPro: IPR013750 - InterPro: IPR006203 - InterPro: IPR006206 - InterPro: IPR020568 - InterPro: IPR014721 [H]
Pfam domain/function: PF10509 GalKase_gal_bdg; PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]
EC number: =2.7.1.6 [H]
Molecular weight: Translated: 45874; Mature: 45874
Theoretical pI: Translated: 7.48; Mature: 7.48
Prosite motif: PS00627 GHMP_KINASES_ATP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIPALHTQQEMLNALHRGALDAGLRALYAPDSDSGHTAAAARIRLENLLHEHLHRYGPRP CCCCCCCHHHHHHHHHHCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC VGIFSAPGRTELAGNHTDHNKGVVVAAAVTLDCLAVASARADLRVHLVSAGFARPVDLTL EEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCH DDLQPRADEKETPAAIVRGMAAGIHGLMPLCGFDACVHSTVPVGAGLSSSAAFEVLCGRI HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH FSGWHSGYVLTQQTLAALAHTAESRYFGKPCGEMDQLACAGSGASVIRFGMPQGKNVEAV HHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCCEEEE PVNIAEAGYQLAVVNTGGSHADLTAEYAAIPAEMRRAAAVLGKQQAHGITAAEVLRHAAA EEEHHHCCEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH IRNAAGDRALLRLLHFAEETQRAEAVAQALRHNRTQELLRLVNASGDSSWRLLQNCYPAG HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHCCCCC ASAQPLPVALETTRLQLDGQGAWRVHGGGFAGTIQVYVPQRLMAGYTKCMEQLFGDGCVI CCCCCCEEEEEEEEEEECCCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCEE PLDIRGSGLHRLLP EEEECCCCHHHCCC >Mature Secondary Structure MIPALHTQQEMLNALHRGALDAGLRALYAPDSDSGHTAAAARIRLENLLHEHLHRYGPRP CCCCCCCHHHHHHHHHHCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC VGIFSAPGRTELAGNHTDHNKGVVVAAAVTLDCLAVASARADLRVHLVSAGFARPVDLTL EEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCH DDLQPRADEKETPAAIVRGMAAGIHGLMPLCGFDACVHSTVPVGAGLSSSAAFEVLCGRI HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH FSGWHSGYVLTQQTLAALAHTAESRYFGKPCGEMDQLACAGSGASVIRFGMPQGKNVEAV HHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEECCCCCCCEEEE PVNIAEAGYQLAVVNTGGSHADLTAEYAAIPAEMRRAAAVLGKQQAHGITAAEVLRHAAA EEEHHHCCEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH IRNAAGDRALLRLLHFAEETQRAEAVAQALRHNRTQELLRLVNASGDSSWRLLQNCYPAG HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHCCCCC ASAQPLPVALETTRLQLDGQGAWRVHGGGFAGTIQVYVPQRLMAGYTKCMEQLFGDGCVI CCCCCCEEEEEEEEEEECCCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCEE PLDIRGSGLHRLLP EEEECCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12000953 [H]