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The map label for this gene is pgi [H]

Identifier: 78358636

GI number: 78358636

Start: 3553217

End: 3554569

Strand: Direct

Name: pgi [H]

Synonym: Dde_3597

Alternate gene names: 78358636

Gene position: 3553217-3554569 (Clockwise)

Preceding gene: 78358635

Following gene: 78358637

Centisome position: 95.25

GC content: 63.34

Gene sequence:

>1353_bases
ATGAGCAACAGCGCCTTTCTTAACTGGACCCACGCCCGTCACGGCCGCATCTCCGGCACAGACCCTGCGTCCCTCACCCC
CCGTCTGGGTGAAGCCGCCAACCTGCTGGGCCTTGAACTGGCCGCGGGCAGGCTGCCGTTCATCGACATGCCGTATGCTG
ACGGCATGACCGCCCGCCTGCAGGAGCTGGAACCGCTGCTGCGCCGTTTTGAACACATGGTGGTGCTGGGCATAGGCGGT
TCCGCGCTGGGTGCCCGCGCGTTGCAGAAGGCTTTTTTTCCCGCGCAGGACAGACCCGCCCACACCGGCCCGTGGCTGTG
GATAGCGGACAACGTGGACGCCGACAGTCTGGAAGCATGGCTGCAGTCACTGCCCGCCGAAAAAACCGTGGTGGTGGTCA
TCAGTAAATCCGGCGGCACCATAGAAACCATCGGGCAGTATTTTCTGATACGCGACTGGCTGCGGACGGCACGCGGCGAC
GCATGGACAAATCATGTCATCGCCGTCACCGACGAACGCAGCGGTTTTCTGCGTGAAGAGGCAGACACGCACGGCCTTGC
ATCCATGCCCGTGCCCGACCATCTGGGCGGACGGTATTCCGTACTTTCCGCCGTGGGGCTCATTCCCGCTGCCTTCACCG
GCATGGACTGGCAGGCGCTTGTACGCGGAGCAAAAACCGTGGGCGCCCCCCTGTGCAGCAGCCCCGATGCGGCCACACTG
GGCGCGCACCCCGCGTGGCATCTGGCCGCATGGAACCACGCGCTCATGCAGGCCGGATACAGCCAGCTCATTTTCTTTTC
ATACATGCCGCTGTGGGCGCACTTCGGATTCTGGTTCGCCCAGCTGTGGGCCGAAAGTCTGGGCAAGGAAGGCAAAGGCT
CCATGCCGCTGCCCGCAGTGGGAGTCACTGACCAGCATTCCACCCAGCAGATGTTTCTGGACGGTCCCCGCGACAAGGCG
TGCCTGTTCCTCACCTGCTCTTCACTGCCGCAGGGGCGCACCTTTCCCGGCGACATGCCCCCCAAGTGGGATTTTCTGCG
GGGCAGACGCTTCGGCGACCTGCTGGAAGCAGAAGCACTGGGCACCCGCATGGCCCTGCACAAAACCGGCACCCCGCTGG
TTGAAATCGGCATGGCGCAGCCATCCGAAGAACAGGCAGGCAGGCTCATGGCCCTGCTTGAAATAACCACACTGCTCACA
GGCTGGCTGCTGGATATCAATCCGCTGGACCAGCCCGCAGTAGAGCTGGGCAAACGGCTGGCAAACGCCAGACTGGGTGC
TCCCGGCTATGATACCGAAACAGCGGACCTCGGCGCATTTCTTGCCGCGCAGGGATCGCGTCAGGAGTTCTAA

Upstream 100 bases:

>100_bases
TAACTCTCCCGATAGGGAATAATGGCCGGCATATGTCCGCCTGTCCGCCTCCCGCGGCAGGCGGTCACATGCCGACCACG
ACAACCAAAGGAGCGAGCAC

Downstream 100 bases:

>100_bases
CCATTGCCAGCATTATACAGCACGGGTGAGCGCCCGCTCCGGTTCGCCCGCTTTCTTTCGTGGGTCTCACTCGTGCTCAT
TCTGGTCACCAGCACGGCGT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSNSAFLNWTHARHGRISGTDPASLTPRLGEAANLLGLELAAGRLPFIDMPYADGMTARLQELEPLLRRFEHMVVLGIGG
SALGARALQKAFFPAQDRPAHTGPWLWIADNVDADSLEAWLQSLPAEKTVVVVISKSGGTIETIGQYFLIRDWLRTARGD
AWTNHVIAVTDERSGFLREEADTHGLASMPVPDHLGGRYSVLSAVGLIPAAFTGMDWQALVRGAKTVGAPLCSSPDAATL
GAHPAWHLAAWNHALMQAGYSQLIFFSYMPLWAHFGFWFAQLWAESLGKEGKGSMPLPAVGVTDQHSTQQMFLDGPRDKA
CLFLTCSSLPQGRTFPGDMPPKWDFLRGRRFGDLLEAEALGTRMALHKTGTPLVEIGMAQPSEEQAGRLMALLEITTLLT
GWLLDINPLDQPAVELGKRLANARLGAPGYDTETADLGAFLAAQGSRQEF

Sequences:

>Translated_450_residues
MSNSAFLNWTHARHGRISGTDPASLTPRLGEAANLLGLELAAGRLPFIDMPYADGMTARLQELEPLLRRFEHMVVLGIGG
SALGARALQKAFFPAQDRPAHTGPWLWIADNVDADSLEAWLQSLPAEKTVVVVISKSGGTIETIGQYFLIRDWLRTARGD
AWTNHVIAVTDERSGFLREEADTHGLASMPVPDHLGGRYSVLSAVGLIPAAFTGMDWQALVRGAKTVGAPLCSSPDAATL
GAHPAWHLAAWNHALMQAGYSQLIFFSYMPLWAHFGFWFAQLWAESLGKEGKGSMPLPAVGVTDQHSTQQMFLDGPRDKA
CLFLTCSSLPQGRTFPGDMPPKWDFLRGRRFGDLLEAEALGTRMALHKTGTPLVEIGMAQPSEEQAGRLMALLEITTLLT
GWLLDINPLDQPAVELGKRLANARLGAPGYDTETADLGAFLAAQGSRQEF
>Mature_449_residues
SNSAFLNWTHARHGRISGTDPASLTPRLGEAANLLGLELAAGRLPFIDMPYADGMTARLQELEPLLRRFEHMVVLGIGGS
ALGARALQKAFFPAQDRPAHTGPWLWIADNVDADSLEAWLQSLPAEKTVVVVISKSGGTIETIGQYFLIRDWLRTARGDA
WTNHVIAVTDERSGFLREEADTHGLASMPVPDHLGGRYSVLSAVGLIPAAFTGMDWQALVRGAKTVGAPLCSSPDAATLG
AHPAWHLAAWNHALMQAGYSQLIFFSYMPLWAHFGFWFAQLWAESLGKEGKGSMPLPAVGVTDQHSTQQMFLDGPRDKAC
LFLTCSSLPQGRTFPGDMPPKWDFLRGRRFGDLLEAEALGTRMALHKTGTPLVEIGMAQPSEEQAGRLMALLEITTLLTG
WLLDINPLDQPAVELGKRLANARLGAPGYDTETADLGAFLAAQGSRQEF

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71996703, Length=385, Percent_Identity=24.1558441558442, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996708, Length=387, Percent_Identity=24.031007751938, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 48844; Mature: 48713

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSAFLNWTHARHGRISGTDPASLTPRLGEAANLLGLELAAGRLPFIDMPYADGMTARL
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHH
QELEPLLRRFEHMVVLGIGGSALGARALQKAFFPAQDRPAHTGPWLWIADNVDADSLEAW
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHH
LQSLPAEKTVVVVISKSGGTIETIGQYFLIRDWLRTARGDAWTNHVIAVTDERSGFLREE
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
ADTHGLASMPVPDHLGGRYSVLSAVGLIPAAFTGMDWQALVRGAKTVGAPLCSSPDAATL
CCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GAHPAWHLAAWNHALMQAGYSQLIFFSYMPLWAHFGFWFAQLWAESLGKEGKGSMPLPAV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GVTDQHSTQQMFLDGPRDKACLFLTCSSLPQGRTFPGDMPPKWDFLRGRRFGDLLEAEAL
CCCCCCCCHHHEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
GTRMALHKTGTPLVEIGMAQPSEEQAGRLMALLEITTLLTGWLLDINPLDQPAVELGKRL
HHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
ANARLGAPGYDTETADLGAFLAAQGSRQEF
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNSAFLNWTHARHGRISGTDPASLTPRLGEAANLLGLELAAGRLPFIDMPYADGMTARL
CCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHH
QELEPLLRRFEHMVVLGIGGSALGARALQKAFFPAQDRPAHTGPWLWIADNVDADSLEAW
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHH
LQSLPAEKTVVVVISKSGGTIETIGQYFLIRDWLRTARGDAWTNHVIAVTDERSGFLREE
HHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
ADTHGLASMPVPDHLGGRYSVLSAVGLIPAAFTGMDWQALVRGAKTVGAPLCSSPDAATL
CCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GAHPAWHLAAWNHALMQAGYSQLIFFSYMPLWAHFGFWFAQLWAESLGKEGKGSMPLPAV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GVTDQHSTQQMFLDGPRDKACLFLTCSSLPQGRTFPGDMPPKWDFLRGRRFGDLLEAEAL
CCCCCCCCHHHEECCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
GTRMALHKTGTPLVEIGMAQPSEEQAGRLMALLEITTLLTGWLLDINPLDQPAVELGKRL
HHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
ANARLGAPGYDTETADLGAFLAAQGSRQEF
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA