Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 78358635

GI number: 78358635

Start: 3551947

End: 3553119

Strand: Direct

Name: aspC [H]

Synonym: Dde_3596

Alternate gene names: 78358635

Gene position: 3551947-3553119 (Clockwise)

Preceding gene: 78358632

Following gene: 78358636

Centisome position: 95.22

GC content: 61.55

Gene sequence:

>1173_bases
ATGAAGATCTCCGACCGTCTTATGCAGGTCAAACCGTCGGCCACTCTGGCCGTCAACGCCAAAGCGCTGGAACTGAAAGC
GCAGGGGCGTGAAATCATCAGCCTTTCCGTGGGCGAGCCGGATGTGCCGCCGCCGGCCCACATCGGCGCAGCCGCCAAAA
AGGCCATTGACGAAAATTTCACCCGCTACACCGCCGTGCCGGGCATTCCCGAACTGCGCGACGCGGTCGCCGGATATTTC
CGGCGGTTTTACGGTGTGGACGCCGCGGCAGAACACACCATTGTGACCAACGGCGGCAAGCAGGCACTGTACAATCTTTT
TCAGGCACTGCTCAACCCCGGCGACGAAGTGCTTATACCCGCTCCGTACTGGGTAAGCTACCCCGCCATGGTGCAGCTGG
CCGGCGGTACGCCCGTGCCTGTGGCTTCAGGGCCGGAAACGGGCTTTAAAACCTGTGTGGAGGAATTGCAGCGCCATATG
ACCCCGCGCACGCGGGTGCTGCTGCTCAATTCACCCTCAAACCCCACAGGCGCATGCTATACCCGCCACGAAATCGACAC
CATCGCCGCATGGGCCATCGAAAACGGGCTGTTCATCATTTCCGACGAAATATACGACCAGCTTGTTTACGCCCCCGCCA
GCCCCGCAGGGCTTGCCCCGTGGTGGCAGAGCAATCCGGAACAGGTGTGCGTGGTCAACGGGCTGGCCAAAAGCTTTTCC
ATGACAGGCTGGCGCGTGGGATATGTGCTGGCGCATCCCGACCTGATCAAAGCACTGGGCAAAATTCAGGGGCAGTCCAC
GTCCAACGTCTGCTCCATAGCCCAGAAGGCGGCACTGGCCGCACTGACAGGCCCGTTTGACGCGCTGGACACCCTGCGCG
AATCCTATGCCCGCCGCCGCGACATCGCTCTGGATATCATATCCGGCTGGAAAAACGTGGTCTGCCCGCGTCCCGACGGC
GCTTTTTATCTGTTCCCCGACGTGCACAGGCTGTACACCGATGCCACGCCGGATTCCGCCACGCTGTGCACCCGCCTCAT
GGAGTCGGCAGGTGTGGCGCTGGTGCCGGGTGCCGCCTTCGGCGACGACCGCTGCGTGCGCATTTCGTATGCGGTTTCGG
AACAGACCCTGCGCGACGCGCTGAGCAAAATAAGCAACGTGCTCTTTTCATAA

Upstream 100 bases:

>100_bases
AATGGCACTGCGGCGTAAAGTCAAATTTACAGCCGGTCGCTAACCTGATAACCACGCCGGTACGAGCACTATTCCAATAC
CAGCATGGGAGAACCCCCCG

Downstream 100 bases:

>100_bases
CTCTCCCGATAGGGAATAATGGCCGGCATATGTCCGCCTGTCCGCCTCCCGCGGCAGGCGGTCACATGCCGACCACGACA
ACCAAAGGAGCGAGCACATG

Product: L-aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKISDRLMQVKPSATLAVNAKALELKAQGREIISLSVGEPDVPPPAHIGAAAKKAIDENFTRYTAVPGIPELRDAVAGYF
RRFYGVDAAAEHTIVTNGGKQALYNLFQALLNPGDEVLIPAPYWVSYPAMVQLAGGTPVPVASGPETGFKTCVEELQRHM
TPRTRVLLLNSPSNPTGACYTRHEIDTIAAWAIENGLFIISDEIYDQLVYAPASPAGLAPWWQSNPEQVCVVNGLAKSFS
MTGWRVGYVLAHPDLIKALGKIQGQSTSNVCSIAQKAALAALTGPFDALDTLRESYARRRDIALDIISGWKNVVCPRPDG
AFYLFPDVHRLYTDATPDSATLCTRLMESAGVALVPGAAFGDDRCVRISYAVSEQTLRDALSKISNVLFS

Sequences:

>Translated_390_residues
MKISDRLMQVKPSATLAVNAKALELKAQGREIISLSVGEPDVPPPAHIGAAAKKAIDENFTRYTAVPGIPELRDAVAGYF
RRFYGVDAAAEHTIVTNGGKQALYNLFQALLNPGDEVLIPAPYWVSYPAMVQLAGGTPVPVASGPETGFKTCVEELQRHM
TPRTRVLLLNSPSNPTGACYTRHEIDTIAAWAIENGLFIISDEIYDQLVYAPASPAGLAPWWQSNPEQVCVVNGLAKSFS
MTGWRVGYVLAHPDLIKALGKIQGQSTSNVCSIAQKAALAALTGPFDALDTLRESYARRRDIALDIISGWKNVVCPRPDG
AFYLFPDVHRLYTDATPDSATLCTRLMESAGVALVPGAAFGDDRCVRISYAVSEQTLRDALSKISNVLFS
>Mature_390_residues
MKISDRLMQVKPSATLAVNAKALELKAQGREIISLSVGEPDVPPPAHIGAAAKKAIDENFTRYTAVPGIPELRDAVAGYF
RRFYGVDAAAEHTIVTNGGKQALYNLFQALLNPGDEVLIPAPYWVSYPAMVQLAGGTPVPVASGPETGFKTCVEELQRHM
TPRTRVLLLNSPSNPTGACYTRHEIDTIAAWAIENGLFIISDEIYDQLVYAPASPAGLAPWWQSNPEQVCVVNGLAKSFS
MTGWRVGYVLAHPDLIKALGKIQGQSTSNVCSIAQKAALAALTGPFDALDTLRESYARRRDIALDIISGWKNVVCPRPDG
AFYLFPDVHRLYTDATPDSATLCTRLMESAGVALVPGAAFGDDRCVRISYAVSEQTLRDALSKISNVLFS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=28.8265306122449, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=28.8265306122449, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI95147551, Length=400, Percent_Identity=27.5, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI169881279, Length=400, Percent_Identity=27.5, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4507369, Length=373, Percent_Identity=27.3458445040214, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI19263340, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI169881281, Length=307, Percent_Identity=25.4071661237785, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4885351, Length=419, Percent_Identity=23.6276849642005, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=28.5326086956522, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=29.7082228116711, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=360, Percent_Identity=28.0555555555556, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=372, Percent_Identity=23.6559139784946, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994949, Length=352, Percent_Identity=24.4318181818182, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=428, Percent_Identity=28.2710280373832, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=428, Percent_Identity=28.2710280373832, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=264, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=24.4736842105263, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=367, Percent_Identity=23.1607629427793, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=162, Percent_Identity=28.3950617283951, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=324, Percent_Identity=26.8518518518519, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=346, Percent_Identity=26.878612716763, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=23.8095238095238, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=23.8095238095238, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=23.8095238095238, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=23.8095238095238, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=26.0526315789474, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551451, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641770, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641760, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641768, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641766, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641764, Length=348, Percent_Identity=26.7241379310345, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42106; Mature: 42106

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISDRLMQVKPSATLAVNAKALELKAQGREIISLSVGEPDVPPPAHIGAAAKKAIDENF
CCCHHHHHEECCCCEEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
TRYTAVPGIPELRDAVAGYFRRFYGVDAAAEHTIVTNGGKQALYNLFQALLNPGDEVLIP
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEC
APYWVSYPAMVQLAGGTPVPVASGPETGFKTCVEELQRHMTPRTRVLLLNSPSNPTGACY
CCHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEE
TRHEIDTIAAWAIENGLFIISDEIYDQLVYAPASPAGLAPWWQSNPEQVCVVNGLAKSFS
EHHHHHHHHHHEECCCEEEEEHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHC
MTGWRVGYVLAHPDLIKALGKIQGQSTSNVCSIAQKAALAALTGPFDALDTLRESYARRR
CCCEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DIALDIISGWKNVVCPRPDGAFYLFPDVHRLYTDATPDSATLCTRLMESAGVALVPGAAF
HHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCC
GDDRCVRISYAVSEQTLRDALSKISNVLFS
CCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKISDRLMQVKPSATLAVNAKALELKAQGREIISLSVGEPDVPPPAHIGAAAKKAIDENF
CCCHHHHHEECCCCEEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCC
TRYTAVPGIPELRDAVAGYFRRFYGVDAAAEHTIVTNGGKQALYNLFQALLNPGDEVLIP
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEC
APYWVSYPAMVQLAGGTPVPVASGPETGFKTCVEELQRHMTPRTRVLLLNSPSNPTGACY
CCHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEE
TRHEIDTIAAWAIENGLFIISDEIYDQLVYAPASPAGLAPWWQSNPEQVCVVNGLAKSFS
EHHHHHHHHHHEECCCEEEEEHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHC
MTGWRVGYVLAHPDLIKALGKIQGQSTSNVCSIAQKAALAALTGPFDALDTLRESYARRR
CCCEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DIALDIISGWKNVVCPRPDGAFYLFPDVHRLYTDATPDSATLCTRLMESAGVALVPGAAF
HHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCC
GDDRCVRISYAVSEQTLRDALSKISNVLFS
CCCCEEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8907187; 10029535 [H]