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The map label for this gene is atoS [H]

Identifier: 78358637

GI number: 78358637

Start: 3554573

End: 3556012

Strand: Direct

Name: atoS [H]

Synonym: Dde_3598

Alternate gene names: 78358637

Gene position: 3554573-3556012 (Clockwise)

Preceding gene: 78358636

Following gene: 78358638

Centisome position: 95.29

GC content: 58.33

Gene sequence:

>1440_bases
TTGCCAGCATTATACAGCACGGGTGAGCGCCCGCTCCGGTTCGCCCGCTTTCTTTCGTGGGTCTCACTCGTGCTCATTCT
GGTCACCAGCACGGCGTTTTCTTTTGTGGTTGCCAACAACGCCCGCAAAACACTGCTGATGAAGCAGAAAGAATACGCCA
TGCTGCTGGGTGAAAACCTTAACAGCCACATATACAAACGCTTTGTGAAGCCCACGCGCCTTGCCTTCGGCAGGGTCGAG
CTTATCAAGCCATTCCAGTACCGCGGCCTTGATCAGGTCATACAGACAACCATCCACGGACTGCAGGTGGATTATCTGCG
CATCTTCGACCACTCGGGCACGGTTTCGTACTCTTCGCGGCTGGAAGAAGTGGGCATGAAAGATCTGGCCGACAGAACCG
TGACCAGAGCTTTTGAAAAAGGCGAACACAGTTTTTCCATTCTCTCGCGCATGTCGCTGCTGCGGGCCATGTTCAGCTTT
GACATGGAGCCGGAAACATTCATCCTGCGCACCACCTTTGTGCTCAAAACCATGGAAGACCGCCTGGACGAAGACGAGCA
GGAAATCATAGGCGTTATGGAGTTCGCGCAGGACATCACCAATGACTACAAGGCCGCCGTCAATTTTCTATGGCTTGTGG
TAGGTGCCTCGCTGGCTTCGTCGCTGACACTTTTTGTACTGCTGGTGACCATTATCCGCAGGGCGGAACGCGCCCTTAAC
GAGCGGCTGCTTGAAAAGGAACGGCTGGAGCGCGACCTGCATCAGAGTGAAAAACTGGCCAGTATGGGCCGCATGGTTGC
CAGCATTGCCCATGAAATACGCAACCCGCTGGGCATCATCAGCTCCAGCGCCGAACTGCTGCTGCGCCGCACCGGCGATG
CCGACCCGCTGACCGGCAGGATACTGCAGGCCATCTTTGACGAAGCAAAGCGTCTGGGGCAGACTGTAAACGACTTTCTG
GATTACGCGCGCCCGAGACGCCCCGGCCGCGACCCCGTGGACATTGCAGCCGTACTGCGTCAGGCCACGGGCTTCATGGA
AGGGGAATTCGCCCGCTCGCAGGTGGCTTTGCATGCCGACCTGCAGGAAGGCCTGCTGGTGGCGGGCGACAAAGACCTGC
TGTACCGCGCTTTTTACAACCTGATGGCCAACAGTCTGCAGGCCATGCAGGGCGGTACGGTGCAGGATGCCACCCTGACC
CTGTGCACCCGCATGACGCGGGACGGGCAGGTGGAAGTACGCATAGCCGACAACGGTCCCGGTTTTCCCCGTCAGGGACG
GGAAAAGCTGCTCGACCCCTTTTACACCACGCGCGATGAAGGCACCGGACTGGGGCTTGCCATCGTCAACAACATAATCA
CAAGCCATGAAGGCTCCATGGAACTGACCGATGCCCCGGAAGGCGGCGCCGAAGTGCGCGTTACCCTGCCCGCGGCATAA

Upstream 100 bases:

>100_bases
GCTGGCAAACGCCAGACTGGGTGCTCCCGGCTATGATACCGAAACAGCGGACCTCGGCGCATTTCTTGCCGCGCAGGGAT
CGCGTCAGGAGTTCTAACCA

Downstream 100 bases:

>100_bases
GCGACGGATGCTATGACCAACGACACGCATATTCTGCTTCTTGACGACGAAAAAAACTATCTTCTGGTGCTGGAAGCGCT
GCTGACCGACGCCGGATACA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MPALYSTGERPLRFARFLSWVSLVLILVTSTAFSFVVANNARKTLLMKQKEYAMLLGENLNSHIYKRFVKPTRLAFGRVE
LIKPFQYRGLDQVIQTTIHGLQVDYLRIFDHSGTVSYSSRLEEVGMKDLADRTVTRAFEKGEHSFSILSRMSLLRAMFSF
DMEPETFILRTTFVLKTMEDRLDEDEQEIIGVMEFAQDITNDYKAAVNFLWLVVGASLASSLTLFVLLVTIIRRAERALN
ERLLEKERLERDLHQSEKLASMGRMVASIAHEIRNPLGIISSSAELLLRRTGDADPLTGRILQAIFDEAKRLGQTVNDFL
DYARPRRPGRDPVDIAAVLRQATGFMEGEFARSQVALHADLQEGLLVAGDKDLLYRAFYNLMANSLQAMQGGTVQDATLT
LCTRMTRDGQVEVRIADNGPGFPRQGREKLLDPFYTTRDEGTGLGLAIVNNIITSHEGSMELTDAPEGGAEVRVTLPAA

Sequences:

>Translated_479_residues
MPALYSTGERPLRFARFLSWVSLVLILVTSTAFSFVVANNARKTLLMKQKEYAMLLGENLNSHIYKRFVKPTRLAFGRVE
LIKPFQYRGLDQVIQTTIHGLQVDYLRIFDHSGTVSYSSRLEEVGMKDLADRTVTRAFEKGEHSFSILSRMSLLRAMFSF
DMEPETFILRTTFVLKTMEDRLDEDEQEIIGVMEFAQDITNDYKAAVNFLWLVVGASLASSLTLFVLLVTIIRRAERALN
ERLLEKERLERDLHQSEKLASMGRMVASIAHEIRNPLGIISSSAELLLRRTGDADPLTGRILQAIFDEAKRLGQTVNDFL
DYARPRRPGRDPVDIAAVLRQATGFMEGEFARSQVALHADLQEGLLVAGDKDLLYRAFYNLMANSLQAMQGGTVQDATLT
LCTRMTRDGQVEVRIADNGPGFPRQGREKLLDPFYTTRDEGTGLGLAIVNNIITSHEGSMELTDAPEGGAEVRVTLPAA
>Mature_478_residues
PALYSTGERPLRFARFLSWVSLVLILVTSTAFSFVVANNARKTLLMKQKEYAMLLGENLNSHIYKRFVKPTRLAFGRVEL
IKPFQYRGLDQVIQTTIHGLQVDYLRIFDHSGTVSYSSRLEEVGMKDLADRTVTRAFEKGEHSFSILSRMSLLRAMFSFD
MEPETFILRTTFVLKTMEDRLDEDEQEIIGVMEFAQDITNDYKAAVNFLWLVVGASLASSLTLFVLLVTIIRRAERALNE
RLLEKERLERDLHQSEKLASMGRMVASIAHEIRNPLGIISSSAELLLRRTGDADPLTGRILQAIFDEAKRLGQTVNDFLD
YARPRRPGRDPVDIAAVLRQATGFMEGEFARSQVALHADLQEGLLVAGDKDLLYRAFYNLMANSLQAMQGGTVQDATLTL
CTRMTRDGQVEVRIADNGPGFPRQGREKLLDPFYTTRDEGTGLGLAIVNNIITSHEGSMELTDAPEGGAEVRVTLPAA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=28.8135593220339, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=27.4074074074074, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=30.952380952381, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=31.9838056680162, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786783, Length=302, Percent_Identity=27.1523178807947, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.0330578512397, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=27.4881516587678, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=24.8979591836735, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=27.0386266094421, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=25.6880733944954, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=27.7533039647577, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53763; Mature: 53631

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALYSTGERPLRFARFLSWVSLVLILVTSTAFSFVVANNARKTLLMKQKEYAMLLGENL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH
NSHIYKRFVKPTRLAFGRVELIKPFQYRGLDQVIQTTIHGLQVDYLRIFDHSGTVSYSSR
HHHHHHHHHCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHCEEHHHEEECCCCCCHHHHH
LEEVGMKDLADRTVTRAFEKGEHSFSILSRMSLLRAMFSFDMEPETFILRTTFVLKTMED
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
RLDEDEQEIIGVMEFAQDITNDYKAAVNFLWLVVGASLASSLTLFVLLVTIIRRAERALN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLLEKERLERDLHQSEKLASMGRMVASIAHEIRNPLGIISSSAELLLRRTGDADPLTGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCCHHHH
ILQAIFDEAKRLGQTVNDFLDYARPRRPGRDPVDIAAVLRQATGFMEGEFARSQVALHAD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQEGLLVAGDKDLLYRAFYNLMANSLQAMQGGTVQDATLTLCTRMTRDGQVEVRIADNGP
HHCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
GFPRQGREKLLDPFYTTRDEGTGLGLAIVNNIITSHEGSMELTDAPEGGAEVRVTLPAA
CCCCCCHHHHCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCC
>Mature Secondary Structure 
PALYSTGERPLRFARFLSWVSLVLILVTSTAFSFVVANNARKTLLMKQKEYAMLLGENL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCH
NSHIYKRFVKPTRLAFGRVELIKPFQYRGLDQVIQTTIHGLQVDYLRIFDHSGTVSYSSR
HHHHHHHHHCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHCEEHHHEEECCCCCCHHHHH
LEEVGMKDLADRTVTRAFEKGEHSFSILSRMSLLRAMFSFDMEPETFILRTTFVLKTMED
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
RLDEDEQEIIGVMEFAQDITNDYKAAVNFLWLVVGASLASSLTLFVLLVTIIRRAERALN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLLEKERLERDLHQSEKLASMGRMVASIAHEIRNPLGIISSSAELLLRRTGDADPLTGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCCHHHH
ILQAIFDEAKRLGQTVNDFLDYARPRRPGRDPVDIAAVLRQATGFMEGEFARSQVALHAD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQEGLLVAGDKDLLYRAFYNLMANSLQAMQGGTVQDATLTLCTRMTRDGQVEVRIADNGP
HHCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
GFPRQGREKLLDPFYTTRDEGTGLGLAIVNNIITSHEGSMELTDAPEGGAEVRVTLPAA
CCCCCCHHHHCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]