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The map label for this gene is atoS [H]

Identifier: 78358574

GI number: 78358574

Start: 3492760

End: 3493992

Strand: Direct

Name: atoS [H]

Synonym: Dde_3535

Alternate gene names: 78358574

Gene position: 3492760-3493992 (Clockwise)

Preceding gene: 78358573

Following gene: 78358575

Centisome position: 93.63

GC content: 54.18

Gene sequence:

>1233_bases
ATGAAAGGCAAAACAACCATAGAAGACCTTGTCGGCATTGAACACAGCAAGCTGAATTTTTTTCAGGAACTCCAGCAGAG
CATTGAGGAACTGAAAGAAAGCAACAAGGAGCTGGAGGAACAGCGCCGCGAAACAGCCGCCATCCTTGACGGCATTACCG
ATGTGATGATGGTGCTTTCCGAAGACCTGCGCATCATCTCGGTAAACCATGTGTTCATGCAGCTGTTCCCCGACAGCGAC
CCCCACGGACAGTACTGCTACAAATACTTCAGGCATTCCCACACCCCCTGCCGCGAGTGTCCCGCGTTCCGCTCGCTCAG
CACAGACACGGTATGCCGCGAGACTGCCATTTTCCGCATCAACGGACGCAACATGCAGTTCGAGATGGTGGCATCGCCGC
TTAAAAGCCCGTACCTGCCCGAACACCGCGTGCTCATTTTCAAACGCGATGTGACACTGGAAAAAGAATATCAGGCGAAA
TTCTATCAGGCCGAAAAAATGGCCACCATGGGTGTGCTGGCAGCCGGTGTCGCACACGAGATAAACAACCCCCTTACGGC
GGTGACAGGCTTTGCCGAAGGCATCCGGCGTCGTCTGCCCAAGCTGCGCGGACTGGTGGATGACCAGCTGTTCACCGACT
TTCAGGAATACACCGACACCATTCTCAAAGAATGTCTGCGCTGTCAGGACATCGTACAGACTCTTCTGACCTTCAGCCGT
CCCTCCTCGGCGGAGTTTTCGCAGCTCAGTCTCAACTCCGTGGTTTCGGAAACAGTCTGGCTGCTGCACAACCACTTCAA
AAAGCATCACAACATCAAGGTCAATCTGAACCTTGACGAAACCGTACCTCATATTTTCGGCGACGAAGCCCAGCTGAAAC
AGGTGGTGCTCAATCTGCTGACCAATGCGCTCGACTCCATGAGCGAAACCGGAAACAAAGACCGCTGCTACTTTTCCGGC
GTGCTGGCCGTGGAAACAGCCCCCTTCGGCGAAAGCGGCGCAAAACTCATTGTCAGCGACACGGGCTGCGGTATTCCGCC
GGACAACATAGACAAACTTTTCGAACCCTTCTTCACCACCAAAAATGTGGGCAAGGGCATCGGCATCGGTCTTTCCACCT
GTTATTCCATAGTCCGCAAGCACGGCGGCGAAATAACCGTCACAAGCACGGAAGGCAAAGGATCGCAATTCACCGTAACG
CTACCCGGCAACCGCGGAGAACAACGTGTCTGA

Upstream 100 bases:

>100_bases
AGCAGATATGCAAAATGGCGGTGCCGGACGAATGCGCACTTACCAACCCGCGCGAAGCCACCTGGGCTGACCTGATGGGG
ATATGCAAAGAGGCCTGGTA

Downstream 100 bases:

>100_bases
CATCTACAGCATTCTGGTCATTGATGACGAAGAATCCATACTGCGACTGCTCGAACGCGAACTGACCACACAGGACCGCA
TTGTCCACACCGCCCAGAAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKGKTTIEDLVGIEHSKLNFFQELQQSIEELKESNKELEEQRRETAAILDGITDVMMVLSEDLRIISVNHVFMQLFPDSD
PHGQYCYKYFRHSHTPCRECPAFRSLSTDTVCRETAIFRINGRNMQFEMVASPLKSPYLPEHRVLIFKRDVTLEKEYQAK
FYQAEKMATMGVLAAGVAHEINNPLTAVTGFAEGIRRRLPKLRGLVDDQLFTDFQEYTDTILKECLRCQDIVQTLLTFSR
PSSAEFSQLSLNSVVSETVWLLHNHFKKHHNIKVNLNLDETVPHIFGDEAQLKQVVLNLLTNALDSMSETGNKDRCYFSG
VLAVETAPFGESGAKLIVSDTGCGIPPDNIDKLFEPFFTTKNVGKGIGIGLSTCYSIVRKHGGEITVTSTEGKGSQFTVT
LPGNRGEQRV

Sequences:

>Translated_410_residues
MKGKTTIEDLVGIEHSKLNFFQELQQSIEELKESNKELEEQRRETAAILDGITDVMMVLSEDLRIISVNHVFMQLFPDSD
PHGQYCYKYFRHSHTPCRECPAFRSLSTDTVCRETAIFRINGRNMQFEMVASPLKSPYLPEHRVLIFKRDVTLEKEYQAK
FYQAEKMATMGVLAAGVAHEINNPLTAVTGFAEGIRRRLPKLRGLVDDQLFTDFQEYTDTILKECLRCQDIVQTLLTFSR
PSSAEFSQLSLNSVVSETVWLLHNHFKKHHNIKVNLNLDETVPHIFGDEAQLKQVVLNLLTNALDSMSETGNKDRCYFSG
VLAVETAPFGESGAKLIVSDTGCGIPPDNIDKLFEPFFTTKNVGKGIGIGLSTCYSIVRKHGGEITVTSTEGKGSQFTVT
LPGNRGEQRV
>Mature_410_residues
MKGKTTIEDLVGIEHSKLNFFQELQQSIEELKESNKELEEQRRETAAILDGITDVMMVLSEDLRIISVNHVFMQLFPDSD
PHGQYCYKYFRHSHTPCRECPAFRSLSTDTVCRETAIFRINGRNMQFEMVASPLKSPYLPEHRVLIFKRDVTLEKEYQAK
FYQAEKMATMGVLAAGVAHEINNPLTAVTGFAEGIRRRLPKLRGLVDDQLFTDFQEYTDTILKECLRCQDIVQTLLTFSR
PSSAEFSQLSLNSVVSETVWLLHNHFKKHHNIKVNLNLDETVPHIFGDEAQLKQVVLNLLTNALDSMSETGNKDRCYFSG
VLAVETAPFGESGAKLIVSDTGCGIPPDNIDKLFEPFFTTKNVGKGIGIGLSTCYSIVRKHGGEITVTSTEGKGSQFTVT
LPGNRGEQRV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=37.0786516853933, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=32.9457364341085, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790300, Length=373, Percent_Identity=25.201072386059, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=402, Percent_Identity=26.1194029850746, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=312, Percent_Identity=27.5641025641026, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=299, Percent_Identity=28.4280936454849, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=398, Percent_Identity=23.1155778894472, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=25.6302521008403, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46163; Mature: 46163

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKTTIEDLVGIEHSKLNFFQELQQSIEELKESNKELEEQRRETAAILDGITDVMMVLS
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLRIISVNHVFMQLFPDSDPHGQYCYKYFRHSHTPCRECPAFRSLSTDTVCRETAIFRI
CCCEEEEHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHCCHHHCCCCHHHHHHEEEEEE
NGRNMQFEMVASPLKSPYLPEHRVLIFKRDVTLEKEYQAKFYQAEKMATMGVLAAGVAHE
CCCCEEHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INNPLTAVTGFAEGIRRRLPKLRGLVDDQLFTDFQEYTDTILKECLRCQDIVQTLLTFSR
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSSAEFSQLSLNSVVSETVWLLHNHFKKHHNIKVNLNLDETVPHIFGDEAQLKQVVLNLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCHHHCCCHHHHHHHHHHHH
TNALDSMSETGNKDRCYFSGVLAVETAPFGESGAKLIVSDTGCGIPPDNIDKLFEPFFTT
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
KNVGKGIGIGLSTCYSIVRKHGGEITVTSTEGKGSQFTVTLPGNRGEQRV
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKGKTTIEDLVGIEHSKLNFFQELQQSIEELKESNKELEEQRRETAAILDGITDVMMVLS
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLRIISVNHVFMQLFPDSDPHGQYCYKYFRHSHTPCRECPAFRSLSTDTVCRETAIFRI
CCCEEEEHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHCCHHHCCCCHHHHHHEEEEEE
NGRNMQFEMVASPLKSPYLPEHRVLIFKRDVTLEKEYQAKFYQAEKMATMGVLAAGVAHE
CCCCEEHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INNPLTAVTGFAEGIRRRLPKLRGLVDDQLFTDFQEYTDTILKECLRCQDIVQTLLTFSR
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSSAEFSQLSLNSVVSETVWLLHNHFKKHHNIKVNLNLDETVPHIFGDEAQLKQVVLNLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCHHHCCCHHHHHHHHHHHH
TNALDSMSETGNKDRCYFSGVLAVETAPFGESGAKLIVSDTGCGIPPDNIDKLFEPFFTT
HHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
KNVGKGIGIGLSTCYSIVRKHGGEITVTSTEGKGSQFTVTLPGNRGEQRV
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]