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The map label for this gene is zraR [H]

Identifier: 78358575

GI number: 78358575

Start: 3493985

End: 3495328

Strand: Direct

Name: zraR [H]

Synonym: Dde_3536

Alternate gene names: 78358575

Gene position: 3493985-3495328 (Clockwise)

Preceding gene: 78358574

Following gene: 78358577

Centisome position: 93.67

GC content: 56.77

Gene sequence:

>1344_bases
GTGTCTGACATCTACAGCATTCTGGTCATTGATGACGAAGAATCCATACTGCGACTGCTCGAACGCGAACTGACCACACA
GGACCGCATTGTCCACACCGCCCAGAACGGACGCGAAGGCCGTGAAAAACTGAGCCGCCAGCGTTATGACGTTGTCATTT
CCGACATCCGCCTGCCCGACGCCGACGGGCTGGACCTCATGGTCGAGCTGAAAGGCATATATCCCGACGTGGAATTCATT
CTTATCACCGGACACGGCAACATAGACAACGCCGTGGAAGCCATGCGTCTGGGCGCCTACGACTATGTGACCAAACCTTT
TCATCTGGACAGGGTGGAACTGGTGGTCGAACGGGCCTACCAGCGGGTATGCCTGCAGCGCGAAAACCGCAGCTTCCGCC
ACTCGCACAGCAGCGCTCCGCCTTCAAAGATGGTCGGTAATTCAGCAGAAATAAAACAGATACGCTATCTGGTCGGCAAA
GTCGCTCCCACCGACGTTCCTGTGCTTATCACCGGCGAAAGCGGCGTGGGCAAAGATGTTGTGGCCCATTCCATTCAGGC
GCTCAGCACCCGAAGCGGCAAGCCTTTTCTGGTGAAAAACTGCGCCACCCTGCAAAAAGAACTGATGCGCAGCGAACTTT
TCGGCCATACCAAAGGCTCGTTCACCGGCGCCACCGACAACCGCGAAGGGCTGCTTGCCTTTGCAGACACCGGCACACTG
TTTCTGGACGAAATCGGCGAACTGCCGCCGGAAGTGCAGGGCGCACTGCTGCGGGTACTGGAGGCCAAACGATACCGCCG
CGTGGGCGAGAAAAGCGAGAGGCAGGTGGATATCCGCTTTCTTTTCGCCACCAGCCGCAACCTGCTGGAAGAAGTGGAGG
CAGGCCGGTTCAATGACGCCCTTTTTCACCGCATCAACGTATTCAACATCTGCGTGGCACCGCTGCGCGACCGCAAAGAA
GACATCCCCCTGCTTGTGGAGCATTTTCTGGGCAGACTGGGCAATGCCATGGGTCACAACGAACTGACCGTCAGTGACAA
AGCCATGCAGTGCCTGCAGCACTACGACTGGCCCGGCAACGTGCGCGAGCTGCGCAACGTGCTGGAGCGCAGTATAATTC
TTTCAGAAAACGGCATCATTTCAGAACGTTCACTGCCGCGCGATCTTGTGGAACGGGCTGAACAGAGCGGGCTGGAAAGC
AGCATCTTTTCGCTGGAACACATGGAGCGTGAACATATCACCCGCGCTCTGGCCTTTTTTAACGGGAACAGACAGCAGGC
ATCCAAGGCGCTGGGCATAGGACGCAAAACCTTGTACCGCAAGCTGGAGCGTTACAATTTGTAA

Upstream 100 bases:

>100_bases
TCCATAGTCCGCAAGCACGGCGGCGAAATAACCGTCACAAGCACGGAAGGCAAAGGATCGCAATTCACCGTAACGCTACC
CGGCAACCGCGGAGAACAAC

Downstream 100 bases:

>100_bases
CCGCAGAACACAAAGAATAACCTATACGCACAGGCGACTTGAAAGATGTGACAAAGTGACTCAACGGCGATATAAAACAG
GGTCACAATGACACACATGA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSDIYSILVIDDEESILRLLERELTTQDRIVHTAQNGREGREKLSRQRYDVVISDIRLPDADGLDLMVELKGIYPDVEFI
LITGHGNIDNAVEAMRLGAYDYVTKPFHLDRVELVVERAYQRVCLQRENRSFRHSHSSAPPSKMVGNSAEIKQIRYLVGK
VAPTDVPVLITGESGVGKDVVAHSIQALSTRSGKPFLVKNCATLQKELMRSELFGHTKGSFTGATDNREGLLAFADTGTL
FLDEIGELPPEVQGALLRVLEAKRYRRVGEKSERQVDIRFLFATSRNLLEEVEAGRFNDALFHRINVFNICVAPLRDRKE
DIPLLVEHFLGRLGNAMGHNELTVSDKAMQCLQHYDWPGNVRELRNVLERSIILSENGIISERSLPRDLVERAEQSGLES
SIFSLEHMEREHITRALAFFNGNRQQASKALGIGRKTLYRKLERYNL

Sequences:

>Translated_447_residues
MSDIYSILVIDDEESILRLLERELTTQDRIVHTAQNGREGREKLSRQRYDVVISDIRLPDADGLDLMVELKGIYPDVEFI
LITGHGNIDNAVEAMRLGAYDYVTKPFHLDRVELVVERAYQRVCLQRENRSFRHSHSSAPPSKMVGNSAEIKQIRYLVGK
VAPTDVPVLITGESGVGKDVVAHSIQALSTRSGKPFLVKNCATLQKELMRSELFGHTKGSFTGATDNREGLLAFADTGTL
FLDEIGELPPEVQGALLRVLEAKRYRRVGEKSERQVDIRFLFATSRNLLEEVEAGRFNDALFHRINVFNICVAPLRDRKE
DIPLLVEHFLGRLGNAMGHNELTVSDKAMQCLQHYDWPGNVRELRNVLERSIILSENGIISERSLPRDLVERAEQSGLES
SIFSLEHMEREHITRALAFFNGNRQQASKALGIGRKTLYRKLERYNL
>Mature_446_residues
SDIYSILVIDDEESILRLLERELTTQDRIVHTAQNGREGREKLSRQRYDVVISDIRLPDADGLDLMVELKGIYPDVEFIL
ITGHGNIDNAVEAMRLGAYDYVTKPFHLDRVELVVERAYQRVCLQRENRSFRHSHSSAPPSKMVGNSAEIKQIRYLVGKV
APTDVPVLITGESGVGKDVVAHSIQALSTRSGKPFLVKNCATLQKELMRSELFGHTKGSFTGATDNREGLLAFADTGTLF
LDEIGELPPEVQGALLRVLEAKRYRRVGEKSERQVDIRFLFATSRNLLEEVEAGRFNDALFHRINVFNICVAPLRDRKED
IPLLVEHFLGRLGNAMGHNELTVSDKAMQCLQHYDWPGNVRELRNVLERSIILSENGIISERSLPRDLVERAEQSGLESS
IFSLEHMEREHITRALAFFNGNRQQASKALGIGRKTLYRKLERYNL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=450, Percent_Identity=40.2222222222222, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1788550, Length=459, Percent_Identity=38.1263616557734, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=36.6952789699571, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=35.8108108108108, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789233, Length=362, Percent_Identity=38.6740331491713, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=39.7515527950311, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=39.4409937888199, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789087, Length=309, Percent_Identity=37.2168284789644, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=37.0253164556962, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1787583, Length=311, Percent_Identity=33.7620578778135, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87081872, Length=304, Percent_Identity=35.5263157894737, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=32.2033898305085, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=38.9830508474576, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=143, Percent_Identity=32.1678321678322, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=31.9672131147541, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=101, Percent_Identity=34.6534653465347, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50690; Mature: 50558

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIYSILVIDDEESILRLLERELTTQDRIVHTAQNGREGREKLSRQRYDVVISDIRLPD
CCCEEEEEEECCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCC
ADGLDLMVELKGIYPDVEFILITGHGNIDNAVEAMRLGAYDYVTKPFHLDRVELVVERAY
CCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHH
QRVCLQRENRSFRHSHSSAPPSKMVGNSAEIKQIRYLVGKVAPTDVPVLITGESGVGKDV
HHHHHHHHCCHHHHCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
VAHSIQALSTRSGKPFLVKNCATLQKELMRSELFGHTKGSFTGATDNREGLLAFADTGTL
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCH
FLDEIGELPPEVQGALLRVLEAKRYRRVGEKSERQVDIRFLFATSRNLLEEVEAGRFNDA
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHH
LFHRINVFNICVAPLRDRKEDIPLLVEHFLGRLGNAMGHNELTVSDKAMQCLQHYDWPGN
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCCCCC
VRELRNVLERSIILSENGIISERSLPRDLVERAEQSGLESSIFSLEHMEREHITRALAFF
HHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NGNRQQASKALGIGRKTLYRKLERYNL
CCCHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SDIYSILVIDDEESILRLLERELTTQDRIVHTAQNGREGREKLSRQRYDVVISDIRLPD
CCEEEEEEECCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCC
ADGLDLMVELKGIYPDVEFILITGHGNIDNAVEAMRLGAYDYVTKPFHLDRVELVVERAY
CCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHH
QRVCLQRENRSFRHSHSSAPPSKMVGNSAEIKQIRYLVGKVAPTDVPVLITGESGVGKDV
HHHHHHHHCCHHHHCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
VAHSIQALSTRSGKPFLVKNCATLQKELMRSELFGHTKGSFTGATDNREGLLAFADTGTL
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCH
FLDEIGELPPEVQGALLRVLEAKRYRRVGEKSERQVDIRFLFATSRNLLEEVEAGRFNDA
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCHH
LFHRINVFNICVAPLRDRKEDIPLLVEHFLGRLGNAMGHNELTVSDKAMQCLQHYDWPGN
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCCCCC
VRELRNVLERSIILSENGIISERSLPRDLVERAEQSGLESSIFSLEHMEREHITRALAFF
HHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NGNRQQASKALGIGRKTLYRKLERYNL
CCCHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]