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The map label for this gene is fmt [H]

Identifier: 78358437

GI number: 78358437

Start: 3361901

End: 3362491

Strand: Direct

Name: fmt [H]

Synonym: Dde_3397

Alternate gene names: 78358437

Gene position: 3361901-3362491 (Clockwise)

Preceding gene: 78358436

Following gene: 78358438

Centisome position: 90.13

GC content: 56.35

Gene sequence:

>591_bases
ATGAAGGTGGCCATCTTAGGACAAGGCTGGTTGGCCACAGAGGTTTTGCACGCGCTAGGCAGAATACCGGCCCTTAGTAT
TGTGGCCGCTTCACCGGAAAAAACTGATGACCGCTTTATGCTTGCCCTAAAACACACGGGGGTTCCGGTCATACCAAACC
TTAAACATCTGCCGCACTGCGACCTCATGGTGGCAGCCCACTGCCATCGTTATATCGGTGCGGGGGCTTTACTCAAAGCC
CGACACGGGATTCTCGCCTATCACCCGTCGCTGCTCCCAAGGCACCGCGGGCGTAACGCAATCCACTGGACGCTGGCCAT
GCGTGATCCCATAGCCGGTGGCTCTGTTTATCTGATGGACGATGGTGTTGATACCGGAGACATTGTCTGCCAAGACTGGT
GCCATGTTCTGCCGAACGATACCCCACAGACCTTGTGGCGGCGCTCTCTGGGGCCAATGGGGGTGCGCCTTCTCACCCAG
GCCGTCACATGGCTTGTAAGAGATGGCACCTTGCATACAATGCGGCAAGATGAACGATGCGCCACATGGGAGCCAGCATT
GGCCCGTGAGCCTCTCAAAAATACAATCTAA

Upstream 100 bases:

>100_bases
TAGCCAGAAGCGCCCGCAAGAGGGGAAAGCAGTCCCCAAAATCGGGTTATGGAGGTCACTTCCGGGCGGTACAGGGCTTT
CGCTACATGGGAGATCGCCC

Downstream 100 bases:

>100_bases
AAACAGGTGCCCCGGAATACCGACCGGGGCACCAAATTTTAACTCTCGAATTTCCCATTTTGAAATGGCAAAATTCTCAA
ATAGAGTGTCAGCTTACACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKVAILGQGWLATEVLHALGRIPALSIVAASPEKTDDRFMLALKHTGVPVIPNLKHLPHCDLMVAAHCHRYIGAGALLKA
RHGILAYHPSLLPRHRGRNAIHWTLAMRDPIAGGSVYLMDDGVDTGDIVCQDWCHVLPNDTPQTLWRRSLGPMGVRLLTQ
AVTWLVRDGTLHTMRQDERCATWEPALAREPLKNTI

Sequences:

>Translated_196_residues
MKVAILGQGWLATEVLHALGRIPALSIVAASPEKTDDRFMLALKHTGVPVIPNLKHLPHCDLMVAAHCHRYIGAGALLKA
RHGILAYHPSLLPRHRGRNAIHWTLAMRDPIAGGSVYLMDDGVDTGDIVCQDWCHVLPNDTPQTLWRRSLGPMGVRLLTQ
AVTWLVRDGTLHTMRQDERCATWEPALAREPLKNTI
>Mature_196_residues
MKVAILGQGWLATEVLHALGRIPALSIVAASPEKTDDRFMLALKHTGVPVIPNLKHLPHCDLMVAAHCHRYIGAGALLKA
RHGILAYHPSLLPRHRGRNAIHWTLAMRDPIAGGSVYLMDDGVDTGDIVCQDWCHVLPNDTPQTLWRRSLGPMGVRLLTQ
AVTWLVRDGTLHTMRQDERCATWEPALAREPLKNTI

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=212, Percent_Identity=36.7924528301887, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI238814322, Length=208, Percent_Identity=35.5769230769231, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI133930964, Length=215, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24585660, Length=207, Percent_Identity=34.7826086956522, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 21740; Mature: 21740

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00373 GART ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAILGQGWLATEVLHALGRIPALSIVAASPEKTDDRFMLALKHTGVPVIPNLKHLPHC
CEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
DLMVAAHCHRYIGAGALLKARHGILAYHPSLLPRHRGRNAIHWTLAMRDPIAGGSVYLMD
HHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHCCCCCEEEEEEEECCCCCCCEEEEEE
DGVDTGDIVCQDWCHVLPNDTPQTLWRRSLGPMGVRLLTQAVTWLVRDGTLHTMRQDERC
CCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCCC
ATWEPALAREPLKNTI
CCCCCHHHHCCHHCCC
>Mature Secondary Structure
MKVAILGQGWLATEVLHALGRIPALSIVAASPEKTDDRFMLALKHTGVPVIPNLKHLPHC
CEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
DLMVAAHCHRYIGAGALLKARHGILAYHPSLLPRHRGRNAIHWTLAMRDPIAGGSVYLMD
HHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHCCCCCEEEEEEEECCCCCCCEEEEEE
DGVDTGDIVCQDWCHVLPNDTPQTLWRRSLGPMGVRLLTQAVTWLVRDGTLHTMRQDERC
CCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCCC
ATWEPALAREPLKNTI
CCCCCHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA