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The map label for this gene is glgP [H]

Identifier: 78358128

GI number: 78358128

Start: 3076705

End: 3079176

Strand: Reverse

Name: glgP [H]

Synonym: Dde_3088

Alternate gene names: 78358128

Gene position: 3079176-3076705 (Counterclockwise)

Preceding gene: 78358129

Following gene: 78358114

Centisome position: 82.55

GC content: 55.18

Gene sequence:

>2472_bases
ATGTCCCGAGTCTGCAAGATGAGCAAGAACGTCAGGGAAGTCTTCAGGCTTGATGAACTGAAAGACGATATCAGGCGCAA
CATGGTGGCGCTGCTGGGCAACGATCCGCGCAGCAAGCGCAAGTTTTCGTATTACAACGCGCTGGCGTACAGCGTGCGCG
AGCGTCTGGTCGACCTGTGGATGCGGACCCAGAGCGATTATTACGATTCCATGGCCAAGCGGGTGTATTATCTTTCCATG
GAATTTCTGCCCGGCCGCTTTCTGATGAACTACCTTACCAACATGGGCATAGTGGATGAGTGCCGCGAGATTGTGGCCGA
GCTGGGTTTTTCGCTGGAAGAGCTGGAAGAGGAGGAATGGGATGCCGGTCTGGGCAACGGCGGGCTGGGGCGTCTTGCCT
CGTGTTATCTCGATTCCATGGTCAGCCAGAATATTCCGGGATACGGGTACGGTATTTTGTATGACTACGGCATATTCTAT
CAGTCCATCGTGAACGGCAATCAGGAAGAGCGCTGCGACAACTGGCGCAGACACGGATGCCCGTGGGAGATAACCCGCCT
TGACACACTGTACGAGGTGAAGTTCTACGGCCGGTCCGAAACTTACTACGACTCTGACGGCAATGTGCGTTTCCGCTGGG
TGGATACGGAAAATGTCATGGCCATGCCGTGCGACATTCTCATTCCCGGATACGGTTGCTCGCATGTTTCCAACATGCGG
CTGTGGACTGCGCAGTCCAGCCGCGAATTCAACCTGTCTGATTTTAACCGCGGCGATTATATAGGGGCCATGCACGGCAA
GGTGATGAGCGAAAACATCACCAAGGTGCTGTATCCCAACGATCAGTTTCTGCAGGGAATGGAACTGCGGCTCAAACAGC
AGTATTTTCTGGTTTCCGCCACGTTTCAGGATATCCTGCGCCGTTATCTGAAGCAGCATACATCGCTTGCCGCACTGCCG
GAGGCGGTTGCGGTGCAGCTTAACGACACACACCCCGCCATAGCCATACCCGAACTTATGCGTCTGCTTATGGACGTGTA
CGGCATGGGCTGGGATGTGGCGTGGGATATCTGCACCCGCACCTTTGCCTATACCAACCACACCGTGCTGCCCGAAGCGC
TGGAAACATGGCCTGTGGACCTGCTGGGCAGGCTGCTGCCGCGGCATATGCAGATAATATATGAAATAAACAGACGTTTT
CTGGAAGGTGTGGCCGCAACATTTCCCGGTGATACCGAGCGCCTTTCACGCATGTCTGTCATTCAGGAAGAAGGAGGCCA
GCGGGTGCGCATGGCCAACCTTGCCATTGTGGGCAGCCATACGGTGAACGGCGTGGCGGCGCTGCACAGCAATATACTGC
AGACCGGTCTGTTCCGTGATTTTCATGAATATTATCCGCGCAAGATACGCAACGTGACCAACGGCGTCACGCCGCGGCGG
TGGCTTATGCAGTGCAATCCTGCTCTTTCGCGGCTGATAACCCAGAGCATAGGGCCGGAATGGTGCTGCAATCTTGAAAA
ACTGCGCGAACTTGTACCTCTGGCGGAAGACAGTGCATTCCGCGATGCATGGGCAAGAGCCAAGCTGGAAAACAAAAGAC
TGCTGTCGCGTTATGTGCTGCGCAAAGTGCAGATGGGCATCAATCCCAACACGTTGTTTGATATGCAGTTTAAACGCATG
CACGAATACAAGCGGCAGCTGCTCAACGTGATGCACGTCATCTCGCTGTTCAACCGCATCAAGGATAACCCCTCGGCGGA
CATCACACCGCGCACGGTGCTTTTCGGCGGCAAGGCAGCCCCCGGATATTATCAGGCCAAGCTTATCATCAGGCTGATCA
ACGAAGTTGCCCGCGTGGTCAACGCCGATGCGGATGTCGCCGGCAGGCTGCGCGTGGCTTTTCTGCCTAATTACTGCATA
TCGCAGGCGGAAAAGGTGGTGCCTGCCGCTGACCTGTCCGAACAGATATCCACCGCCGGCATGGAGGCTTCCGGCACGGG
CAATATGAAGTTTGCGCTTAACGGAGCGTTGACCATAGGCACGCTGGACGGTGCCAATGTGGAAATAATGGAGGAAGTGG
GAGCCGAAAATATTTTTATATTCGGCCTCAAGGCGCATGAAGTGGCGGAAAAAAGGCGTTCCGGATACAACCCCCGGGAA
TTTTATGAAAACGATGCAGAGCTGCGCCGGGTGATGGATATGATCGGTTCGGGCTTTTTTTCTCCCGACGAACGCGGGTT
GTTCAGCCCTGTGTATGACAGCCTGATGCACCACGGCGACTATTACATGCTTATGGCCGATTACCGTCCCTACATGGAGG
CGCAGGCCGCTGTGGACGCGCTGTACCTTGATCAGGACCAGTGGGTACGCAAGTCCATTCTCAATGCCGCCAACATGGGT
AAATTTTCCAGCGACCGTTCGGTCATGGAGTATGCCCGCGGCATCTGGCATGTGGAGCCTCTCGGCAAATAG

Upstream 100 bases:

>100_bases
CTTATAACGTTTCGCAGCTGTACACCGCCGCCCGGGGCAGCTACTATGAAGGTATTACCCGCCGGCAGACCGCTGTGTCG
CCGTGCAACAAGGAGGCCTC

Downstream 100 bases:

>100_bases
CCTGCCGCCTTGTACGCTGAACCCGCACGGGATGCATGTTCCGTGCGGGTTTTCTGTGGCGGATGTCTGCGGCAGCAGTT
CATGTTTTTTCAGGCGTGCT

Product: glycogen/starch/alpha-glucan phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 823; Mature: 822

Protein sequence:

>823_residues
MSRVCKMSKNVREVFRLDELKDDIRRNMVALLGNDPRSKRKFSYYNALAYSVRERLVDLWMRTQSDYYDSMAKRVYYLSM
EFLPGRFLMNYLTNMGIVDECREIVAELGFSLEELEEEEWDAGLGNGGLGRLASCYLDSMVSQNIPGYGYGILYDYGIFY
QSIVNGNQEERCDNWRRHGCPWEITRLDTLYEVKFYGRSETYYDSDGNVRFRWVDTENVMAMPCDILIPGYGCSHVSNMR
LWTAQSSREFNLSDFNRGDYIGAMHGKVMSENITKVLYPNDQFLQGMELRLKQQYFLVSATFQDILRRYLKQHTSLAALP
EAVAVQLNDTHPAIAIPELMRLLMDVYGMGWDVAWDICTRTFAYTNHTVLPEALETWPVDLLGRLLPRHMQIIYEINRRF
LEGVAATFPGDTERLSRMSVIQEEGGQRVRMANLAIVGSHTVNGVAALHSNILQTGLFRDFHEYYPRKIRNVTNGVTPRR
WLMQCNPALSRLITQSIGPEWCCNLEKLRELVPLAEDSAFRDAWARAKLENKRLLSRYVLRKVQMGINPNTLFDMQFKRM
HEYKRQLLNVMHVISLFNRIKDNPSADITPRTVLFGGKAAPGYYQAKLIIRLINEVARVVNADADVAGRLRVAFLPNYCI
SQAEKVVPAADLSEQISTAGMEASGTGNMKFALNGALTIGTLDGANVEIMEEVGAENIFIFGLKAHEVAEKRRSGYNPRE
FYENDAELRRVMDMIGSGFFSPDERGLFSPVYDSLMHHGDYYMLMADYRPYMEAQAAVDALYLDQDQWVRKSILNAANMG
KFSSDRSVMEYARGIWHVEPLGK

Sequences:

>Translated_823_residues
MSRVCKMSKNVREVFRLDELKDDIRRNMVALLGNDPRSKRKFSYYNALAYSVRERLVDLWMRTQSDYYDSMAKRVYYLSM
EFLPGRFLMNYLTNMGIVDECREIVAELGFSLEELEEEEWDAGLGNGGLGRLASCYLDSMVSQNIPGYGYGILYDYGIFY
QSIVNGNQEERCDNWRRHGCPWEITRLDTLYEVKFYGRSETYYDSDGNVRFRWVDTENVMAMPCDILIPGYGCSHVSNMR
LWTAQSSREFNLSDFNRGDYIGAMHGKVMSENITKVLYPNDQFLQGMELRLKQQYFLVSATFQDILRRYLKQHTSLAALP
EAVAVQLNDTHPAIAIPELMRLLMDVYGMGWDVAWDICTRTFAYTNHTVLPEALETWPVDLLGRLLPRHMQIIYEINRRF
LEGVAATFPGDTERLSRMSVIQEEGGQRVRMANLAIVGSHTVNGVAALHSNILQTGLFRDFHEYYPRKIRNVTNGVTPRR
WLMQCNPALSRLITQSIGPEWCCNLEKLRELVPLAEDSAFRDAWARAKLENKRLLSRYVLRKVQMGINPNTLFDMQFKRM
HEYKRQLLNVMHVISLFNRIKDNPSADITPRTVLFGGKAAPGYYQAKLIIRLINEVARVVNADADVAGRLRVAFLPNYCI
SQAEKVVPAADLSEQISTAGMEASGTGNMKFALNGALTIGTLDGANVEIMEEVGAENIFIFGLKAHEVAEKRRSGYNPRE
FYENDAELRRVMDMIGSGFFSPDERGLFSPVYDSLMHHGDYYMLMADYRPYMEAQAAVDALYLDQDQWVRKSILNAANMG
KFSSDRSVMEYARGIWHVEPLGK
>Mature_822_residues
SRVCKMSKNVREVFRLDELKDDIRRNMVALLGNDPRSKRKFSYYNALAYSVRERLVDLWMRTQSDYYDSMAKRVYYLSME
FLPGRFLMNYLTNMGIVDECREIVAELGFSLEELEEEEWDAGLGNGGLGRLASCYLDSMVSQNIPGYGYGILYDYGIFYQ
SIVNGNQEERCDNWRRHGCPWEITRLDTLYEVKFYGRSETYYDSDGNVRFRWVDTENVMAMPCDILIPGYGCSHVSNMRL
WTAQSSREFNLSDFNRGDYIGAMHGKVMSENITKVLYPNDQFLQGMELRLKQQYFLVSATFQDILRRYLKQHTSLAALPE
AVAVQLNDTHPAIAIPELMRLLMDVYGMGWDVAWDICTRTFAYTNHTVLPEALETWPVDLLGRLLPRHMQIIYEINRRFL
EGVAATFPGDTERLSRMSVIQEEGGQRVRMANLAIVGSHTVNGVAALHSNILQTGLFRDFHEYYPRKIRNVTNGVTPRRW
LMQCNPALSRLITQSIGPEWCCNLEKLRELVPLAEDSAFRDAWARAKLENKRLLSRYVLRKVQMGINPNTLFDMQFKRMH
EYKRQLLNVMHVISLFNRIKDNPSADITPRTVLFGGKAAPGYYQAKLIIRLINEVARVVNADADVAGRLRVAFLPNYCIS
QAEKVVPAADLSEQISTAGMEASGTGNMKFALNGALTIGTLDGANVEIMEEVGAENIFIFGLKAHEVAEKRRSGYNPREF
YENDAELRRVMDMIGSGFFSPDERGLFSPVYDSLMHHGDYYMLMADYRPYMEAQAAVDALYLDQDQWVRKSILNAANMGK
FSSDRSVMEYARGIWHVEPLGK

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=810, Percent_Identity=54.0740740740741, Blast_Score=855, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=810, Percent_Identity=53.4567901234568, Blast_Score=853, Evalue=0.0,
Organism=Homo sapiens, GI71037379, Length=810, Percent_Identity=52.4691358024691, Blast_Score=840, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=810, Percent_Identity=50.4938271604938, Blast_Score=789, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=668, Percent_Identity=54.7904191616767, Blast_Score=751, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=808, Percent_Identity=51.2376237623762, Blast_Score=851, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=748, Percent_Identity=47.7272727272727, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=822, Percent_Identity=51.2165450121654, Blast_Score=846, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=822, Percent_Identity=51.2165450121654, Blast_Score=845, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=862, Percent_Identity=46.2877030162413, Blast_Score=721, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=820, Percent_Identity=52.8048780487805, Blast_Score=852, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=820, Percent_Identity=52.8048780487805, Blast_Score=852, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 94487; Mature: 94356

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVCKMSKNVREVFRLDELKDDIRRNMVALLGNDPRSKRKFSYYNALAYSVRERLVDLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MRTQSDYYDSMAKRVYYLSMEFLPGRFLMNYLTNMGIVDECREIVAELGFSLEELEEEEW
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
DAGLGNGGLGRLASCYLDSMVSQNIPGYGYGILYDYGIFYQSIVNGNQEERCDNWRRHGC
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
PWEITRLDTLYEVKFYGRSETYYDSDGNVRFRWVDTENVMAMPCDILIPGYGCSHVSNMR
CEEEEECCEEEEEEEECCCCCEECCCCCEEEEEECCCCCEECCCCEEECCCCCCCCCCCE
LWTAQSSREFNLSDFNRGDYIGAMHGKVMSENITKVLYPNDQFLQGMELRLKQQYFLVSA
EEECCCCCCCCCCCCCCCCEEEHHHCHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
TFQDILRRYLKQHTSLAALPEAVAVQLNDTHPAIAIPELMRLLMDVYGMGWDVAWDICTR
HHHHHHHHHHHHHCHHHHCCHHEEEEECCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHH
TFAYTNHTVLPEALETWPVDLLGRLLPRHMQIIYEINRRFLEGVAATFPGDTERLSRMSV
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IQEEGGQRVRMANLAIVGSHTVNGVAALHSNILQTGLFRDFHEYYPRKIRNVTNGVTPRR
HHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
WLMQCNPALSRLITQSIGPEWCCNLEKLRELVPLAEDSAFRDAWARAKLENKRLLSRYVL
HHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKVQMGINPNTLFDMQFKRMHEYKRQLLNVMHVISLFNRIKDNPSADITPRTVLFGGKAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
PGYYQAKLIIRLINEVARVVNADADVAGRLRVAFLPNYCISQAEKVVPAADLSEQISTAG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHCC
MEASGTGNMKFALNGALTIGTLDGANVEIMEEVGAENIFIFGLKAHEVAEKRRSGYNPRE
CCCCCCCCEEEEEECEEEEEECCCCCHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCHHH
FYENDAELRRVMDMIGSGFFSPDERGLFSPVYDSLMHHGDYYMLMADYRPYMEAQAAVDA
HHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LYLDQDQWVRKSILNAANMGKFSSDRSVMEYARGIWHVEPLGK
HHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRVCKMSKNVREVFRLDELKDDIRRNMVALLGNDPRSKRKFSYYNALAYSVRERLVDLW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MRTQSDYYDSMAKRVYYLSMEFLPGRFLMNYLTNMGIVDECREIVAELGFSLEELEEEEW
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
DAGLGNGGLGRLASCYLDSMVSQNIPGYGYGILYDYGIFYQSIVNGNQEERCDNWRRHGC
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
PWEITRLDTLYEVKFYGRSETYYDSDGNVRFRWVDTENVMAMPCDILIPGYGCSHVSNMR
CEEEEECCEEEEEEEECCCCCEECCCCCEEEEEECCCCCEECCCCEEECCCCCCCCCCCE
LWTAQSSREFNLSDFNRGDYIGAMHGKVMSENITKVLYPNDQFLQGMELRLKQQYFLVSA
EEECCCCCCCCCCCCCCCCEEEHHHCHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
TFQDILRRYLKQHTSLAALPEAVAVQLNDTHPAIAIPELMRLLMDVYGMGWDVAWDICTR
HHHHHHHHHHHHHCHHHHCCHHEEEEECCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHH
TFAYTNHTVLPEALETWPVDLLGRLLPRHMQIIYEINRRFLEGVAATFPGDTERLSRMSV
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IQEEGGQRVRMANLAIVGSHTVNGVAALHSNILQTGLFRDFHEYYPRKIRNVTNGVTPRR
HHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
WLMQCNPALSRLITQSIGPEWCCNLEKLRELVPLAEDSAFRDAWARAKLENKRLLSRYVL
HHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKVQMGINPNTLFDMQFKRMHEYKRQLLNVMHVISLFNRIKDNPSADITPRTVLFGGKAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
PGYYQAKLIIRLINEVARVVNADADVAGRLRVAFLPNYCISQAEKVVPAADLSEQISTAG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHCC
MEASGTGNMKFALNGALTIGTLDGANVEIMEEVGAENIFIFGLKAHEVAEKRRSGYNPRE
CCCCCCCCEEEEEECEEEEEECCCCCHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCHHH
FYENDAELRRVMDMIGSGFFSPDERGLFSPVYDSLMHHGDYYMLMADYRPYMEAQAAVDA
HHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
LYLDQDQWVRKSILNAANMGKFSSDRSVMEYARGIWHVEPLGK
HHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2645169; 3047129; 9278503; 2975249; 3097003 [H]