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The map label for this gene is apeA [H]

Identifier: 78358101

GI number: 78358101

Start: 3052660

End: 3054054

Strand: Direct

Name: apeA [H]

Synonym: Dde_3061

Alternate gene names: 78358101

Gene position: 3052660-3054054 (Clockwise)

Preceding gene: 78358100

Following gene: 78358102

Centisome position: 81.84

GC content: 58.71

Gene sequence:

>1395_bases
ATGAACGCAAAGCTGGAACATACCCCCAAAAGCTGCTGGGAAATATACGGTACTGAAGAACACGCACAGCCCATGGACGA
GCTGGCAGAACGATACATCGACTTTATATCGCGCTGCAAAACAGAGCGGGAAACCATGGAATATGTTGTGGAACGGCTGC
GCAGCGCAGGATACACGCAGAACTTCGCACATGACCGCGTCTACCGCGTGTTCAAAGACAAAACCATTTTCATCGCTGCC
AAAGGCCGCAACTCGATTTCGCAGGGGCTGCGGCTCATCGGAGCGCACGCCGACACGCCGCGCATCGACCTGAAACAGCA
CCCGCTGTACGAAGCCTGCGGCGTCGGACAGGCAAAAACCCACTACTACGGCGGCATCCGCAAATACCAGTGGCTTTCGC
GCCCGCTGGCCCTGCACGGAGTGGTGGTAAAGGAAGACGGTACCGTCGTGCAGGTCAACGTGGGCGATGACGCCGGTGAC
CCGGTATTCGCCATATCCGACCTGCTGCCCCATCTGGCGCAGAAACAGTCGGGCCAGACGCTCTCCGAAGCGTTTGAAGC
GGAAAAAATGAATATCATCCTTGCCCACCGCCCTGTGGAAAATGCCGCAGACAGCAAAGACGCAGACACACAGCAGCCCC
CCAAGGAAAAAATTAAAGCACGTATTCTTGAAATACTGCACGCCAAATACGGCATAGTGGAGGAAGACCTGTATTCTGCC
GAACTGCAGGCCGTACCGGCCGGTCCCGCACGGTATGTGGGGCTGGACAGCGCGCTTATCGGCGGCTACGGGCAGGACGA
CCGCATATGCGTGTTTGCCGCTCTGGAAGCCCTGCTGCAGGACGGCACGCCGGAATACACCCGCTGTGTGCTGTTCTGGG
ACAAAGAGGAAATCGGTTCCGAAGGCTCCACCGGCGCCAAGTCGCGATTTTTTGAATACTGCATAGCCGACCTCATTGCG
GCATGGCAGCCCGCGGCGCGTTTTTCCGATGTAATGCTGAACACCCGTGCCATTTCCGCCGATGTGCACGGCGCCATGGA
CCCCGACTGGCAGGACCTGCATGAAAAACTCAATGCGGCCATCATCGGATACGGTCCCTGCTTCTGCAAATTCACCGGAC
ACCGCGGCAAGTACGAGGCCAACGACGCCCATCCGGAATATGTGGGCTGGCTGCGCGGGGTGCTGAATGAACAGGGCATA
CCATGGCAGATGGCGGAACTGGGCCGCGTTGATCTGGGCGGCGGCGGCACCGTGGCCATGTATCTTGCGGCCTACGGCAT
GGACATCATAGACTTCGGTCCGGCCATTCTGGGCATGCACAGCCCGTTCGAGCTGGCAAGCAAGGCCGACCTGTACGCCA
CGGTCAAAGCCTACGGCGCTTTTCTGATGTGCTGA

Upstream 100 bases:

>100_bases
AGATATACGCTGACCAGACGGCTGCGCGATGCCGCAGCCGCATCACAGCACAAAACCGGACTTTTTTGTGCACCCACTGA
ATCACCGGAGAAACATTCGC

Downstream 100 bases:

>100_bases
CACCAAGGGCGGCAGCGGAGCATCTTCCGCTGCCGCTTTTTTTTCATCTCCGCAGGCCCGTTCCCGTCCCCGTTCCCGTC
CCTGTGCCCGTCACCGGACC

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNAKLEHTPKSCWEIYGTEEHAQPMDELAERYIDFISRCKTERETMEYVVERLRSAGYTQNFAHDRVYRVFKDKTIFIAA
KGRNSISQGLRLIGAHADTPRIDLKQHPLYEACGVGQAKTHYYGGIRKYQWLSRPLALHGVVVKEDGTVVQVNVGDDAGD
PVFAISDLLPHLAQKQSGQTLSEAFEAEKMNIILAHRPVENAADSKDADTQQPPKEKIKARILEILHAKYGIVEEDLYSA
ELQAVPAGPARYVGLDSALIGGYGQDDRICVFAALEALLQDGTPEYTRCVLFWDKEEIGSEGSTGAKSRFFEYCIADLIA
AWQPAARFSDVMLNTRAISADVHGAMDPDWQDLHEKLNAAIIGYGPCFCKFTGHRGKYEANDAHPEYVGWLRGVLNEQGI
PWQMAELGRVDLGGGGTVAMYLAAYGMDIIDFGPAILGMHSPFELASKADLYATVKAYGAFLMC

Sequences:

>Translated_464_residues
MNAKLEHTPKSCWEIYGTEEHAQPMDELAERYIDFISRCKTERETMEYVVERLRSAGYTQNFAHDRVYRVFKDKTIFIAA
KGRNSISQGLRLIGAHADTPRIDLKQHPLYEACGVGQAKTHYYGGIRKYQWLSRPLALHGVVVKEDGTVVQVNVGDDAGD
PVFAISDLLPHLAQKQSGQTLSEAFEAEKMNIILAHRPVENAADSKDADTQQPPKEKIKARILEILHAKYGIVEEDLYSA
ELQAVPAGPARYVGLDSALIGGYGQDDRICVFAALEALLQDGTPEYTRCVLFWDKEEIGSEGSTGAKSRFFEYCIADLIA
AWQPAARFSDVMLNTRAISADVHGAMDPDWQDLHEKLNAAIIGYGPCFCKFTGHRGKYEANDAHPEYVGWLRGVLNEQGI
PWQMAELGRVDLGGGGTVAMYLAAYGMDIIDFGPAILGMHSPFELASKADLYATVKAYGAFLMC
>Mature_464_residues
MNAKLEHTPKSCWEIYGTEEHAQPMDELAERYIDFISRCKTERETMEYVVERLRSAGYTQNFAHDRVYRVFKDKTIFIAA
KGRNSISQGLRLIGAHADTPRIDLKQHPLYEACGVGQAKTHYYGGIRKYQWLSRPLALHGVVVKEDGTVVQVNVGDDAGD
PVFAISDLLPHLAQKQSGQTLSEAFEAEKMNIILAHRPVENAADSKDADTQQPPKEKIKARILEILHAKYGIVEEDLYSA
ELQAVPAGPARYVGLDSALIGGYGQDDRICVFAALEALLQDGTPEYTRCVLFWDKEEIGSEGSTGAKSRFFEYCIADLIA
AWQPAARFSDVMLNTRAISADVHGAMDPDWQDLHEKLNAAIIGYGPCFCKFTGHRGKYEANDAHPEYVGWLRGVLNEQGI
PWQMAELGRVDLGGGGTVAMYLAAYGMDIIDFGPAILGMHSPFELASKADLYATVKAYGAFLMC

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=454, Percent_Identity=25.1101321585903, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17552916, Length=465, Percent_Identity=24.3010752688172, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322746, Length=474, Percent_Identity=24.8945147679325, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51408; Mature: 51408

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKLEHTPKSCWEIYGTEEHAQPMDELAERYIDFISRCKTERETMEYVVERLRSAGYTQ
CCCCCCCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
NFAHDRVYRVFKDKTIFIAAKGRNSISQGLRLIGAHADTPRIDLKQHPLYEACGVGQAKT
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHEEECCCCCCCCCCCCCCCHHHHCCCCCCH
HYYGGIRKYQWLSRPLALHGVVVKEDGTVVQVNVGDDAGDPVFAISDLLPHLAQKQSGQT
HHHCCHHHHHHHCCCHHHEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCH
LSEAFEAEKMNIILAHRPVENAADSKDADTQQPPKEKIKARILEILHAKYGIVEEDLYSA
HHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ELQAVPAGPARYVGLDSALIGGYGQDDRICVFAALEALLQDGTPEYTRCVLFWDKEEIGS
HHEECCCCCCCEECCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHCC
EGSTGAKSRFFEYCIADLIAAWQPAARFSDVMLNTRAISADVHGAMDPDWQDLHEKLNAA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHCEE
IIGYGPCFCKFTGHRGKYEANDAHPEYVGWLRGVLNEQGIPWQMAELGRVDLGGGGTVAM
EEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCEECCCCCHHHH
YLAAYGMDIIDFGPAILGMHSPFELASKADLYATVKAYGAFLMC
HHHHHCCHHHHCCHHHHCCCCCHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAKLEHTPKSCWEIYGTEEHAQPMDELAERYIDFISRCKTERETMEYVVERLRSAGYTQ
CCCCCCCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
NFAHDRVYRVFKDKTIFIAAKGRNSISQGLRLIGAHADTPRIDLKQHPLYEACGVGQAKT
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHEEECCCCCCCCCCCCCCCHHHHCCCCCCH
HYYGGIRKYQWLSRPLALHGVVVKEDGTVVQVNVGDDAGDPVFAISDLLPHLAQKQSGQT
HHHCCHHHHHHHCCCHHHEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCH
LSEAFEAEKMNIILAHRPVENAADSKDADTQQPPKEKIKARILEILHAKYGIVEEDLYSA
HHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ELQAVPAGPARYVGLDSALIGGYGQDDRICVFAALEALLQDGTPEYTRCVLFWDKEEIGS
HHEECCCCCCCEECCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHCC
EGSTGAKSRFFEYCIADLIAAWQPAARFSDVMLNTRAISADVHGAMDPDWQDLHEKLNAA
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHCEE
IIGYGPCFCKFTGHRGKYEANDAHPEYVGWLRGVLNEQGIPWQMAELGRVDLGGGGTVAM
EEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCEECCCCCHHHH
YLAAYGMDIIDFGPAILGMHSPFELASKADLYATVKAYGAFLMC
HHHHHCCHHHHCCHHHHCCCCCHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]