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The map label for this gene is hybB [C]

Identifier: 78357975

GI number: 78357975

Start: 2916093

End: 2917349

Strand: Direct

Name: hybB [C]

Synonym: Dde_2935

Alternate gene names: 78357975

Gene position: 2916093-2917349 (Clockwise)

Preceding gene: 78357974

Following gene: 78357986

Centisome position: 78.17

GC content: 55.93

Gene sequence:

>1257_bases
ATGGAAAAGAACTACGATCTTCCCGTTGATCACGAGCTGTTCCCCGAGGGAACCAAACGCTGTTCCTTCAGCAAGTTCTC
CGTATGGATGGCTGTCGTGGGTGTGGTGCTGGCGTGGGGCGTATACGCCGCCTTCCGCGTACTGCGCTACGGTCTTGGCG
AAACAGCTCTTGACGACTACTTCGGTTTCGGCCTGTGGATCACCTTTGACCTTGCGGTCATCGCTCTGGGTGCCGGCGCG
TTTTTCACCGGATTACTGCGCTACATCCTGAACATTGATCCGCTCAAACACATCATCAACCTTGCAGTTATCATCGGCTT
TATCTGCTATTCCGGCGCCATGCTTATTCTGGTGCTGGATATCGGGCAGCCGCTCAGGGCATGGTTCGGCTACTGGCACG
CCAACGTCCATTCCATGCTGACAGAAGTTATCTTCTGCATCACCTGCTACTGCATCGTACTGATAATTGAGTACATTCCC
CTGATTCTTGAACAGCGTCAGCTGAACAAGATCCCCTTCCTGCATCATCTGGCGCACAACCTTCACGTTGTCATGCCGCT
GTTTGCAGGTGTGGGCGCATTCCTTTCCACGTTCCACCAGGGTTCGCTGGGCGGTATGTACGGCGTGCTTTTCGGCCGCC
CCTACGTACTGCGTGACGGGTTCTTCATCTGGCCGTGGACATTCTTCCTGTTTGTCATTTCCGCAGTGGGCTCCGGTCCG
GTGTTCACCGTGCTTGTGGCCACGCTGATGGAAAAAATGACCGGCAAAAAACTGGTCAGCTGGGAAGTGAAGTCCCTCAT
GGGCAAAATAGCCGGTACCATGCTGGCTGTGTATCTGGTATTCAAGTTCGCCGACACATGGGCATGGGCTACCGATGTTC
TGCCCCGTTCGGGTCTGACATTTGACCAGAACTTCTTCGGCACCATTTACGGCAAGTGGCTGCTCTGGGCCGAGCTGGGC
CTGTGCGGGGTCATTCCTGCCATCATGCTGCTTACCCCCAGTCTGCGCAACCGTCCGGGCCTGTTCTATACGGCTGCCAT
TCTGGACTGCGTGGGCATCACCATCAACCGTTACGTCTTCACCGTTCAGGCGCTGGCCATGCCGGTCATGCCCTTTGACA
CGTGGGAAACGTACAACCCGAACTGGGCCGAGTGGGGAGCCAGTGCAATGGTCATCGCGTACGGTGCCATCATCCTGAGC
CTCTCCTACCGCTATCTGCCTGTTTTCCCCCAGGAAAAGAAGCTGAACGCGGAATAG

Upstream 100 bases:

>100_bases
TGGGTGCCGACACGCAGGTGTACTACCTCAGCCGTCGCGAATGGGTCCGCCGTCTTGGCGACAACTATCTTGAACACGAA
AAGGTCAAGGGGTAGCTCTC

Downstream 100 bases:

>100_bases
TCATGTCGAATTGAAAGCTTGAAGTCAGGCGGAGCGGGGTTGTCCCGCTCCGCTTTTTTATGCACAGCAAACGCTCTGCA
GCGACAAAGTTTCATCATCA

Product: molybdopterin oxidoreductase, transmembrane subunit

Products: NA

Alternate protein names: HMC operon ORF 3 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEKNYDLPVDHELFPEGTKRCSFSKFSVWMAVVGVVLAWGVYAAFRVLRYGLGETALDDYFGFGLWITFDLAVIALGAGA
FFTGLLRYILNIDPLKHIINLAVIIGFICYSGAMLILVLDIGQPLRAWFGYWHANVHSMLTEVIFCITCYCIVLIIEYIP
LILEQRQLNKIPFLHHLAHNLHVVMPLFAGVGAFLSTFHQGSLGGMYGVLFGRPYVLRDGFFIWPWTFFLFVISAVGSGP
VFTVLVATLMEKMTGKKLVSWEVKSLMGKIAGTMLAVYLVFKFADTWAWATDVLPRSGLTFDQNFFGTIYGKWLLWAELG
LCGVIPAIMLLTPSLRNRPGLFYTAAILDCVGITINRYVFTVQALAMPVMPFDTWETYNPNWAEWGASAMVIAYGAIILS
LSYRYLPVFPQEKKLNAE

Sequences:

>Translated_418_residues
MEKNYDLPVDHELFPEGTKRCSFSKFSVWMAVVGVVLAWGVYAAFRVLRYGLGETALDDYFGFGLWITFDLAVIALGAGA
FFTGLLRYILNIDPLKHIINLAVIIGFICYSGAMLILVLDIGQPLRAWFGYWHANVHSMLTEVIFCITCYCIVLIIEYIP
LILEQRQLNKIPFLHHLAHNLHVVMPLFAGVGAFLSTFHQGSLGGMYGVLFGRPYVLRDGFFIWPWTFFLFVISAVGSGP
VFTVLVATLMEKMTGKKLVSWEVKSLMGKIAGTMLAVYLVFKFADTWAWATDVLPRSGLTFDQNFFGTIYGKWLLWAELG
LCGVIPAIMLLTPSLRNRPGLFYTAAILDCVGITINRYVFTVQALAMPVMPFDTWETYNPNWAEWGASAMVIAYGAIILS
LSYRYLPVFPQEKKLNAE
>Mature_418_residues
MEKNYDLPVDHELFPEGTKRCSFSKFSVWMAVVGVVLAWGVYAAFRVLRYGLGETALDDYFGFGLWITFDLAVIALGAGA
FFTGLLRYILNIDPLKHIINLAVIIGFICYSGAMLILVLDIGQPLRAWFGYWHANVHSMLTEVIFCITCYCIVLIIEYIP
LILEQRQLNKIPFLHHLAHNLHVVMPLFAGVGAFLSTFHQGSLGGMYGVLFGRPYVLRDGFFIWPWTFFLFVISAVGSGP
VFTVLVATLMEKMTGKKLVSWEVKSLMGKIAGTMLAVYLVFKFADTWAWATDVLPRSGLTFDQNFFGTIYGKWLLWAELG
LCGVIPAIMLLTPSLRNRPGLFYTAAILDCVGITINRYVFTVQALAMPVMPFDTWETYNPNWAEWGASAMVIAYGAIILS
LSYRYLPVFPQEKKLNAE

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI2367183, Length=394, Percent_Identity=23.3502538071066, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 47001; Mature: 47001

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]