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The map label for this gene is atoS [H]

Identifier: 78357873

GI number: 78357873

Start: 2818097

End: 2820334

Strand: Direct

Name: atoS [H]

Synonym: Dde_2832

Alternate gene names: 78357873

Gene position: 2818097-2820334 (Clockwise)

Preceding gene: 78357872

Following gene: 78357881

Centisome position: 75.55

GC content: 59.07

Gene sequence:

>2238_bases
ATGAAAACCACCCAGCTGCCTTCGCTTTCGCGGACCATGTCTGTCAAGCTTATCCGCTGGATGTGCGTGCTGGGAATGCT
CTGCGCGCTTTTTCTGGCCGCATTCTCCTACCAGAGCCGCATCAGCGAATTCGAAGCGCGCAGCCGCTACAACGCCGGAA
TCATCGCCAACTACATCAATGAATATATGCAGGGTGCCTACGCCGCGCTGCAAAACACCATGGACGAACCCGACGGCACA
CTGCCGCACACCATGACCATGCTGAAAAGGCTGTACCCGCAGTTCACCAGAGTCATGCTGGTGGACGGCAACCGCAAAAT
AACCACCAGTGTGCCCCCGGCACTGCCGGGGCAGGAACTGGCTGTCCCTCTGCTGCCGGTTGCTGTGGCCGGCGGAGTCA
TCAGCCAGCCGCAGGGCATGACCGATGCCGGAGACATGGGGGTGTATCTGGGCGTAAAGCAGCAGGACGGCTCCATGCTG
GTGGCCGAGCTGCACCTGCGGGCCGTGCAGAAGCATCTTGCAGAGCTGTTTCCCAAAGAATCAAGTCTGCTGGTACTGAC
AGATGCATGGGGCAACACCATGGTGCACCCCGACTGGGCCATGGTGCGGCGTTTTGCCAACATAGGTCTGCAGCCGGTCT
TTCATGCCACCCGCGACACGGGATCATTCTTCGGCAAGACGGAATCCGAAGGCCGCCTGTTGCAGGTTTCGGCCATGCGC
ATCGCTTCCACAGGGTGGGTCATTCTGCACATAATGCCCACCATGAATGTGATCACGGGCACCGCGCGCGACATACTGGC
CTTTGTGGCGGTGTTTGCCGCGCTGTATACAGTTCTCGCCGCATCGCTGCTGTACGAGCTGCAGCGCGGGCTTGCGCGCC
CGCTCAGAGAATTCACCAGAACCATCAAGGACATTTCTGTGGGAGCATGGCCGGGCAGATCCGGCAGCCCGGAAACCTAT
GATGAATTTCAGGAAATGCGCCTTGAATTTGACAACATGTCCGCAGCGCTGGAGGAACGCGAGGCGGATCTCACCCGGGC
GCACCTTTTTGTCCAGAACATCATAGACGCCATGCCTTCCGTTGTTGTGGCTCTGGATACACAGGGGCATGTCACCCATA
TGAACAGGCGCGCGGCAGAACGCATGCAGCACAACGCACCCGCCGGCAAAACCCTGCTGCCCATCGAAGCCATTGCCCCG
CAGATTTCACCGTTTCTGCCGCAGCTGCACCATGCCCTGCACACCCGCACCCCCCTTGAGCTGCACCTGACAGGCAAAGA
CGCCGACGGCAGCACCGTGCATGAAGAAGTGCAGCTGGCCCCGCTGCCCGGCGAATCCGAAGGCGGCGTACTGCGCATAG
ACGATGTGACGCAGCGCATCCAGCTGGAAGAAATGATGATTCAGACTGAAAAAATGATGTCTGTGGGCGGGCTTGCAGCG
GGTATGGCCCACGAGATCAACAACCCGCTGGGTGCCATACTGCAGGGAACCCAGAATATCCGCAGGCGCATCACCGACAC
GCTGCCTGCAAATATCGCTGCCGCACAGAAGGCGGGGTGCTCCATGCAGGCCGTTCAGGCCTATATGCACGAAAGAAAAA
TTCCCGATTTTCTGCAGGGCATACAGGAATCCGGCCAGCGTGCCGCCAACATAGTATCAAATATGCTTACATTTTCACGC
CGCAGCGATGCCAGCCCCACCACAGCCAATCTGCATGCGGCGCTGGACCGCACGGTACAGCTGGCTTCCAGCGACTATGA
TCTGAAAAAAAAATACGACTTCAGGCAGGTGCACATCGTCCGCGAGTTTGCGGACGATGTGGGAGACATCATCTGTCACC
CCATTGAGCTGGAGCAGGTGGTGCTCAACCTGCTGCGCAATGCCGCCCAGTCCGTGGCCACGCAGGGAGCGGCACTGAAA
GAAACGGGCGCGGAAGAGTACAGGCCCACCATACACCTGCGCACACGCAGAGAAGACGACTGGGCAGTCATCGAAATAGA
AGACAACGGCACCGGCATGTCCGCCGCCACCCGGAGGCGCATATTCGAGCCGTTCTTTACCACCAAGCAGGCGGGTCAGG
GCACCGGACTGGGGCTTTCGGTCTCATATTTCATCATTACCAAAAACCATGGCGGCACCCTGACGGTGGATTCGCAGGAA
GGAGAAGGAACCACCTTCACCATCCGCATTCCTGTAAACGGACCGGCCGCCGTGCGCACGCAGGATAGCTTCACCTAA

Upstream 100 bases:

>100_bases
TGGATGGTCTGTGCGGCCCCATCACGCTGGATGCATACGGAGACGCACACATGCCGTTCTTCATTTCCACAGTGCGCAAC
GGCGCATTCGAGCCGGTACG

Downstream 100 bases:

>100_bases
ACGGGGTTCAGTCGCGCCCCAGCAGCATCACGGAGCCGAGTCCACCCAGCAGCAGGCCTGTTACCAGATTCAGCGCGCCC
TGCCTGCCGTCGTAGACCCG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MKTTQLPSLSRTMSVKLIRWMCVLGMLCALFLAAFSYQSRISEFEARSRYNAGIIANYINEYMQGAYAALQNTMDEPDGT
LPHTMTMLKRLYPQFTRVMLVDGNRKITTSVPPALPGQELAVPLLPVAVAGGVISQPQGMTDAGDMGVYLGVKQQDGSML
VAELHLRAVQKHLAELFPKESSLLVLTDAWGNTMVHPDWAMVRRFANIGLQPVFHATRDTGSFFGKTESEGRLLQVSAMR
IASTGWVILHIMPTMNVITGTARDILAFVAVFAALYTVLAASLLYELQRGLARPLREFTRTIKDISVGAWPGRSGSPETY
DEFQEMRLEFDNMSAALEEREADLTRAHLFVQNIIDAMPSVVVALDTQGHVTHMNRRAAERMQHNAPAGKTLLPIEAIAP
QISPFLPQLHHALHTRTPLELHLTGKDADGSTVHEEVQLAPLPGESEGGVLRIDDVTQRIQLEEMMIQTEKMMSVGGLAA
GMAHEINNPLGAILQGTQNIRRRITDTLPANIAAAQKAGCSMQAVQAYMHERKIPDFLQGIQESGQRAANIVSNMLTFSR
RSDASPTTANLHAALDRTVQLASSDYDLKKKYDFRQVHIVREFADDVGDIICHPIELEQVVLNLLRNAAQSVATQGAALK
ETGAEEYRPTIHLRTRREDDWAVIEIEDNGTGMSAATRRRIFEPFFTTKQAGQGTGLGLSVSYFIITKNHGGTLTVDSQE
GEGTTFTIRIPVNGPAAVRTQDSFT

Sequences:

>Translated_745_residues
MKTTQLPSLSRTMSVKLIRWMCVLGMLCALFLAAFSYQSRISEFEARSRYNAGIIANYINEYMQGAYAALQNTMDEPDGT
LPHTMTMLKRLYPQFTRVMLVDGNRKITTSVPPALPGQELAVPLLPVAVAGGVISQPQGMTDAGDMGVYLGVKQQDGSML
VAELHLRAVQKHLAELFPKESSLLVLTDAWGNTMVHPDWAMVRRFANIGLQPVFHATRDTGSFFGKTESEGRLLQVSAMR
IASTGWVILHIMPTMNVITGTARDILAFVAVFAALYTVLAASLLYELQRGLARPLREFTRTIKDISVGAWPGRSGSPETY
DEFQEMRLEFDNMSAALEEREADLTRAHLFVQNIIDAMPSVVVALDTQGHVTHMNRRAAERMQHNAPAGKTLLPIEAIAP
QISPFLPQLHHALHTRTPLELHLTGKDADGSTVHEEVQLAPLPGESEGGVLRIDDVTQRIQLEEMMIQTEKMMSVGGLAA
GMAHEINNPLGAILQGTQNIRRRITDTLPANIAAAQKAGCSMQAVQAYMHERKIPDFLQGIQESGQRAANIVSNMLTFSR
RSDASPTTANLHAALDRTVQLASSDYDLKKKYDFRQVHIVREFADDVGDIICHPIELEQVVLNLLRNAAQSVATQGAALK
ETGAEEYRPTIHLRTRREDDWAVIEIEDNGTGMSAATRRRIFEPFFTTKQAGQGTGLGLSVSYFIITKNHGGTLTVDSQE
GEGTTFTIRIPVNGPAAVRTQDSFT
>Mature_745_residues
MKTTQLPSLSRTMSVKLIRWMCVLGMLCALFLAAFSYQSRISEFEARSRYNAGIIANYINEYMQGAYAALQNTMDEPDGT
LPHTMTMLKRLYPQFTRVMLVDGNRKITTSVPPALPGQELAVPLLPVAVAGGVISQPQGMTDAGDMGVYLGVKQQDGSML
VAELHLRAVQKHLAELFPKESSLLVLTDAWGNTMVHPDWAMVRRFANIGLQPVFHATRDTGSFFGKTESEGRLLQVSAMR
IASTGWVILHIMPTMNVITGTARDILAFVAVFAALYTVLAASLLYELQRGLARPLREFTRTIKDISVGAWPGRSGSPETY
DEFQEMRLEFDNMSAALEEREADLTRAHLFVQNIIDAMPSVVVALDTQGHVTHMNRRAAERMQHNAPAGKTLLPIEAIAP
QISPFLPQLHHALHTRTPLELHLTGKDADGSTVHEEVQLAPLPGESEGGVLRIDDVTQRIQLEEMMIQTEKMMSVGGLAA
GMAHEINNPLGAILQGTQNIRRRITDTLPANIAAAQKAGCSMQAVQAYMHERKIPDFLQGIQESGQRAANIVSNMLTFSR
RSDASPTTANLHAALDRTVQLASSDYDLKKKYDFRQVHIVREFADDVGDIICHPIELEQVVLNLLRNAAQSVATQGAALK
ETGAEEYRPTIHLRTRREDDWAVIEIEDNGTGMSAATRRRIFEPFFTTKQAGQGTGLGLSVSYFIITKNHGGTLTVDSQE
GEGTTFTIRIPVNGPAAVRTQDSFT

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=420, Percent_Identity=28.3333333333333, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1790436, Length=272, Percent_Identity=30.5147058823529, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790300, Length=272, Percent_Identity=24.2647058823529, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=125, Percent_Identity=36, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=28.4615384615385, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82024; Mature: 82024

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50885 HAMP ; PS00041 HTH_ARAC_FAMILY_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTQLPSLSRTMSVKLIRWMCVLGMLCALFLAAFSYQSRISEFEARSRYNAGIIANYIN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYMQGAYAALQNTMDEPDGTLPHTMTMLKRLYPQFTRVMLVDGNRKITTSVPPALPGQEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCCCCCCC
AVPLLPVAVAGGVISQPQGMTDAGDMGVYLGVKQQDGSMLVAELHLRAVQKHLAELFPKE
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
SSLLVLTDAWGNTMVHPDWAMVRRFANIGLQPVFHATRDTGSFFGKTESEGRLLQVSAMR
CCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEHHH
IASTGWVILHIMPTMNVITGTARDILAFVAVFAALYTVLAASLLYELQRGLARPLREFTR
HCCCCEEEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIKDISVGAWPGRSGSPETYDEFQEMRLEFDNMSAALEEREADLTRAHLFVQNIIDAMPS
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVVALDTQGHVTHMNRRAAERMQHNAPAGKTLLPIEAIAPQISPFLPQLHHALHTRTPLE
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCCEE
LHLTGKDADGSTVHEEVQLAPLPGESEGGVLRIDDVTQRIQLEEMMIQTEKMMSVGGLAA
EEEECCCCCCCHHHHHEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMAHEINNPLGAILQGTQNIRRRITDTLPANIAAAQKAGCSMQAVQAYMHERKIPDFLQG
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IQESGQRAANIVSNMLTFSRRSDASPTTANLHAALDRTVQLASSDYDLKKKYDFRQVHIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHH
REFADDVGDIICHPIELEQVVLNLLRNAAQSVATQGAALKETGAEEYRPTIHLRTRREDD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCEEEEEECCCCC
WAVIEIEDNGTGMSAATRRRIFEPFFTTKQAGQGTGLGLSVSYFIITKNHGGTLTVDSQE
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCC
GEGTTFTIRIPVNGPAAVRTQDSFT
CCCCEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MKTTQLPSLSRTMSVKLIRWMCVLGMLCALFLAAFSYQSRISEFEARSRYNAGIIANYIN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EYMQGAYAALQNTMDEPDGTLPHTMTMLKRLYPQFTRVMLVDGNRKITTSVPPALPGQEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCCCCCCC
AVPLLPVAVAGGVISQPQGMTDAGDMGVYLGVKQQDGSMLVAELHLRAVQKHLAELFPKE
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
SSLLVLTDAWGNTMVHPDWAMVRRFANIGLQPVFHATRDTGSFFGKTESEGRLLQVSAMR
CCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEHHH
IASTGWVILHIMPTMNVITGTARDILAFVAVFAALYTVLAASLLYELQRGLARPLREFTR
HCCCCEEEEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIKDISVGAWPGRSGSPETYDEFQEMRLEFDNMSAALEEREADLTRAHLFVQNIIDAMPS
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVVALDTQGHVTHMNRRAAERMQHNAPAGKTLLPIEAIAPQISPFLPQLHHALHTRTPLE
EEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCCEE
LHLTGKDADGSTVHEEVQLAPLPGESEGGVLRIDDVTQRIQLEEMMIQTEKMMSVGGLAA
EEEECCCCCCCHHHHHEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMAHEINNPLGAILQGTQNIRRRITDTLPANIAAAQKAGCSMQAVQAYMHERKIPDFLQG
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
IQESGQRAANIVSNMLTFSRRSDASPTTANLHAALDRTVQLASSDYDLKKKYDFRQVHIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHH
REFADDVGDIICHPIELEQVVLNLLRNAAQSVATQGAALKETGAEEYRPTIHLRTRREDD
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCEEEEEECCCCC
WAVIEIEDNGTGMSAATRRRIFEPFFTTKQAGQGTGLGLSVSYFIITKNHGGTLTVDSQE
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCC
GEGTTFTIRIPVNGPAAVRTQDSFT
CCCCEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]