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The map label for this gene is groES

Identifier: 78357517

GI number: 78357517

Start: 2494437

End: 2494724

Strand: Reverse

Name: groES

Synonym: Dde_2474

Alternate gene names: 78357517

Gene position: 2494724-2494437 (Counterclockwise)

Preceding gene: 78357519

Following gene: 78357516

Centisome position: 66.88

GC content: 55.9

Gene sequence:

>288_bases
ATGAACCTGAAGCCTTTGAACGATCGTGTGCTGGTTAAGCGCCTTGAGTCCGAAGAAAAGACCGCAGGCGGCCTGTACAT
TCCCGACACCGCGAAGGAAAAGCCTTCCCGTGGTGAAGTGATCGCAGTCGGCCCCGGCAAGACCGCAGACGACGGCAAGG
TAATTGCCATGACCGTGAAGACCGGCGACGTGGTGCTGTTCAACAAGTACGCAGGCACCGAAGTGAAGCTGGACGGCGTT
GACCATCTGGTCATGCGTGAAGACGACATTCTGGCTATCATTCAGTAA

Upstream 100 bases:

>100_bases
GCAGGTGCGTGGGTGAATGTGCTGCTTTCCTTTGGCACTCGCGTGAAGAGAGTGCTAAAAAAGGGCAAAAAGAGTTAAAT
AATCTGGAGGTTAGGAGAGT

Downstream 100 bases:

>100_bases
CTGACTTTCCCACTGACTTAGTCCTATCCTTTCAGGAGGAGAAGAAATATGGCTTCCAAAGAAATCGTTTTTGATACCAA
GGCCCGTGAAAGACTGGCCC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVIAVGPGKTADDGKVIAMTVKTGDVVLFNKYAGTEVKLDGV
DHLVMREDDILAIIQ

Sequences:

>Translated_95_residues
MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVIAVGPGKTADDGKVIAMTVKTGDVVLFNKYAGTEVKLDGV
DHLVMREDDILAIIQ
>Mature_95_residues
MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVIAVGPGKTADDGKVIAMTVKTGDVVLFNKYAGTEVKLDGV
DHLVMREDDILAIIQ

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=47.9166666666667, Blast_Score=90, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=38.2978723404255, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=45.0549450549451, Blast_Score=78, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=43.956043956044, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=40.8602150537634, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_DESDG (Q30YH5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388966.1
- ProteinModelPortal:   Q30YH5
- SMR:   Q30YH5
- STRING:   Q30YH5
- GeneID:   3757490
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2474
- NMPDR:   fig|207559.3.peg.3200
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   FGQYAGQ
- ProtClustDB:   PRK00364
- BioCyc:   DDES207559:DDE_2474-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10307; Mature: 10307

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVIAVGPGKTADDGKVIAMTVK
CCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEC
TGDVVLFNKYAGTEVKLDGVDHLVMREDDILAIIQ
CCCEEEEECCCCCEEEECCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVIAVGPGKTADDGKVIAMTVK
CCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEC
TGDVVLFNKYAGTEVKLDGVDHLVMREDDILAIIQ
CCCEEEEECCCCCEEEECCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA