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The map label for this gene is dmsB [H]

Identifier: 78357128

GI number: 78357128

Start: 2132795

End: 2133301

Strand: Reverse

Name: dmsB [H]

Synonym: Dde_2085

Alternate gene names: 78357128

Gene position: 2133301-2132795 (Counterclockwise)

Preceding gene: 78357129

Following gene: 78357125

Centisome position: 57.19

GC content: 54.64

Gene sequence:

>507_bases
ATGTCCTGTGAAGGGAAAACTCTTTTTATTGATTACAGCCGCTGTATCGGCTGTGAAAGTTGCGAGGCTGTCTGTAAATT
TTTGTACGATACGCCGCGCATAGCCATGACTCGTACAGTTGAAGGCATCATGGTTCCTCTGTACTGCAAGCACTGCGAAC
AGGCACATTGCATGAAAGTGTGCAACCGCGGGGCGCTGATGCGTGACAGAGACGGAGCCGTTGTGCTGCAGCCGCTGCTG
TGCCGCGGGTGCGAAACCCGCAACTGTATTCTGGCGTGTCCGTATGCCGCATTTTTTGCCACTGATCTCGGTGTCACGGT
GCAAAAATGTGACCTGTGTGCTTCCAGACGGGATGTGGGGCTTGAGCCTGCCTGTGTGGAAATGTGCCCGTGCGAGGCCA
TCATGCTGGTTGACAGGGACTCTGTTCCTGACATGGAGACTGAAGAGTCACGCCGGGCTTATGAACGGGTCATGGCCCAT
ATCCGGCCGCCGGCCAGAAAAAAATGA

Upstream 100 bases:

>100_bases
CCAACTGGCTTGACCTGAAGGCGCAGAACCGCGAGGGCGAATACAGATACGACGAGGACAGAATTGTCCCCTAGCCAGCA
TAGCTCGGAGGCTCAATGTA

Downstream 100 bases:

>100_bases
CCGTGTTGTCCGTTTACCGGCTGCTGTCATGCGGCCATAAAAAAGGGAAGCATCTGCTTCCCTTTTTTATGGCCGAGCTG
CCGGAATGTTATTCGTTGCG

Product: iron-sulfur cluster-binding protein

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSCEGKTLFIDYSRCIGCESCEAVCKFLYDTPRIAMTRTVEGIMVPLYCKHCEQAHCMKVCNRGALMRDRDGAVVLQPLL
CRGCETRNCILACPYAAFFATDLGVTVQKCDLCASRRDVGLEPACVEMCPCEAIMLVDRDSVPDMETEESRRAYERVMAH
IRPPARKK

Sequences:

>Translated_168_residues
MSCEGKTLFIDYSRCIGCESCEAVCKFLYDTPRIAMTRTVEGIMVPLYCKHCEQAHCMKVCNRGALMRDRDGAVVLQPLL
CRGCETRNCILACPYAAFFATDLGVTVQKCDLCASRRDVGLEPACVEMCPCEAIMLVDRDSVPDMETEESRRAYERVMAH
IRPPARKK
>Mature_167_residues
SCEGKTLFIDYSRCIGCESCEAVCKFLYDTPRIAMTRTVEGIMVPLYCKHCEQAHCMKVCNRGALMRDRDGAVVLQPLLC
RGCETRNCILACPYAAFFATDLGVTVQKCDLCASRRDVGLEPACVEMCPCEAIMLVDRDSVPDMETEESRRAYERVMAHI
RPPARKK

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=146, Percent_Identity=36.986301369863, Blast_Score=86, Evalue=9e-19,
Organism=Escherichia coli, GI1787872, Length=148, Percent_Identity=35.8108108108108, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789067, Length=176, Percent_Identity=32.9545454545455, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI2367345, Length=156, Percent_Identity=35.2564102564103, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI226510944, Length=157, Percent_Identity=32.484076433121, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787749, Length=182, Percent_Identity=31.3186813186813, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788811, Length=163, Percent_Identity=31.2883435582822, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87082180, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI87082179, Length=171, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790326, Length=168, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87082114, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367245, Length=152, Percent_Identity=30.2631578947368, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789079, Length=178, Percent_Identity=29.7752808988764, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 18876; Mature: 18745

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

10.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
16.1 %Cys+Met (Translated Protein)
10.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
15.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCEGKTLFIDYSRCIGCESCEAVCKFLYDTPRIAMTRTVEGIMVPLYCKHCEQAHCMKV
CCCCCCEEEEEHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
CNRGALMRDRDGAVVLQPLLCRGCETRNCILACPYAAFFATDLGVTVQKCDLCASRRDVG
HCCCCCEECCCCCEEEHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCC
LEPACVEMCPCEAIMLVDRDSVPDMETEESRRAYERVMAHIRPPARKK
CCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SCEGKTLFIDYSRCIGCESCEAVCKFLYDTPRIAMTRTVEGIMVPLYCKHCEQAHCMKV
CCCCCEEEEEHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHH
CNRGALMRDRDGAVVLQPLLCRGCETRNCILACPYAAFFATDLGVTVQKCDLCASRRDVG
HCCCCCEECCCCCEEEHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHCCCC
LEPACVEMCPCEAIMLVDRDSVPDMETEESRRAYERVMAHIRPPARKK
CCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]