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The map label for this gene is birA [H]

Identifier: 78357125

GI number: 78357125

Start: 2129061

End: 2129975

Strand: Reverse

Name: birA [H]

Synonym: Dde_2082

Alternate gene names: 78357125

Gene position: 2129975-2129061 (Counterclockwise)

Preceding gene: 78357128

Following gene: 78357124

Centisome position: 57.1

GC content: 56.5

Gene sequence:

>915_bases
ATGAATGAGGTAGTAATGTCCTTTCCCGTGTACATTCTTTCAAAGCTGCAGGGCTGCAGCATGCGTCCTCTTGCCCCTGA
GGCCCTCGGGGGAGCGCATGCCCTCTGGCAGCGTGACGTGCGGCTTTTGCCCGCTTTTGAGCCGTGCCGCAATGAAGTTT
ATGAAGGATATGCCACCAGCGGTGGCCCCGGTTGCGGTGCGGTTTTCATCTGCGACGGAGTGGGGTCTTCACTGGATGCC
GCTCATGCGTTGCACGCTGCCGGAGAACTGCCGGTGTGGACAAGTGTGCTTGCAGTTTCGCAGCAGTCAGGAAGAGGCCA
GATGCGCCGTCAGTGGGTGTCGCCGGCAGGCAACATATATGCTGCGCTGCGTTTTCCCGCCGCTTCAAACTATCCTGATT
CGCTTTCTTCGCTGGTTGCGGGCTATGTGTTTGCCAGAGCGTTTGAAATGTGCGGTATTGATGTGCGCATGAAGTGGCCC
AATGATCTGCTGCTGGACGACTGCAAAATGGCAGGAATTCTGCTGGAAGATCGCAACGGTGCGCTGCTTGTGGGAATAGG
TATAAATGTAGCGCACTTTCCCCGGGCAGACTGCCTGCGTGAGGGGGCTGCGGTGCCCGCCTGCGGATTGGCTGCAAGGG
GTTTCGATTTCGCGCCTTTTGAATTGTGGCGACAGCTTGTCGACCGTGCTTTTTTTTGCTACCGTAATGAGGTTCTTCGC
TTCAGTGAAGATGGCTTGATCAGTCGCTTGGAAGCGTATCTTGCCTGGGTAGGCCGTGTTGTGATGATACACGGGAGTGA
TTTAGGGAGCTGTCCGGGCAGGTTAATGGGCTTGAGCCATGATGGAGCGTTGCGCGTACTCCTGTCCGGTCGGGAGCAGG
TCCTCCACTCCTGCAGTCTTTCCCCTATATCATGA

Upstream 100 bases:

>100_bases
ACCGCACCGCCTACAAGGAATGTCTGCATAGGTTCCGGTACCATATATCGCCGCGGCACAAAAGGGCCGCGGCGTTGCGC
GCAGGGTGTTTTTTCCGTGT

Downstream 100 bases:

>100_bases
CACCGTCGTGCCTGAATGAAACTCTAGTGATCGTTGTAACCCCGGTCGTCTATGCAATGGGCTCCGGTTGTTTTGTTGAG
TACGAGGAGTGAATGGCTAT

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNEVVMSFPVYILSKLQGCSMRPLAPEALGGAHALWQRDVRLLPAFEPCRNEVYEGYATSGGPGCGAVFICDGVGSSLDA
AHALHAAGELPVWTSVLAVSQQSGRGQMRRQWVSPAGNIYAALRFPAASNYPDSLSSLVAGYVFARAFEMCGIDVRMKWP
NDLLLDDCKMAGILLEDRNGALLVGIGINVAHFPRADCLREGAAVPACGLAARGFDFAPFELWRQLVDRAFFCYRNEVLR
FSEDGLISRLEAYLAWVGRVVMIHGSDLGSCPGRLMGLSHDGALRVLLSGREQVLHSCSLSPIS

Sequences:

>Translated_304_residues
MNEVVMSFPVYILSKLQGCSMRPLAPEALGGAHALWQRDVRLLPAFEPCRNEVYEGYATSGGPGCGAVFICDGVGSSLDA
AHALHAAGELPVWTSVLAVSQQSGRGQMRRQWVSPAGNIYAALRFPAASNYPDSLSSLVAGYVFARAFEMCGIDVRMKWP
NDLLLDDCKMAGILLEDRNGALLVGIGINVAHFPRADCLREGAAVPACGLAARGFDFAPFELWRQLVDRAFFCYRNEVLR
FSEDGLISRLEAYLAWVGRVVMIHGSDLGSCPGRLMGLSHDGALRVLLSGREQVLHSCSLSPIS
>Mature_304_residues
MNEVVMSFPVYILSKLQGCSMRPLAPEALGGAHALWQRDVRLLPAFEPCRNEVYEGYATSGGPGCGAVFICDGVGSSLDA
AHALHAAGELPVWTSVLAVSQQSGRGQMRRQWVSPAGNIYAALRFPAASNYPDSLSSLVAGYVFARAFEMCGIDVRMKWP
NDLLLDDCKMAGILLEDRNGALLVGIGINVAHFPRADCLREGAAVPACGLAARGFDFAPFELWRQLVDRAFFCYRNEVLR
FSEDGLISRLEAYLAWVGRVVMIHGSDLGSCPGRLMGLSHDGALRVLLSGREQVLHSCSLSPIS

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=118, Percent_Identity=39.8305084745763, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 32878; Mature: 32878

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVVMSFPVYILSKLQGCSMRPLAPEALGGAHALWQRDVRLLPAFEPCRNEVYEGYATS
CCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHCHHCCCCCHHHHHHHHCCCCCC
GGPGCGAVFICDGVGSSLDAAHALHAAGELPVWTSVLAVSQQSGRGQMRRQWVSPAGNIY
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEE
AALRFPAASNYPDSLSSLVAGYVFARAFEMCGIDVRMKWPNDLLLDDCKMAGILLEDRNG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHEEEEEECCCC
ALLVGIGINVAHFPRADCLREGAAVPACGLAARGFDFAPFELWRQLVDRAFFCYRNEVLR
EEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FSEDGLISRLEAYLAWVGRVVMIHGSDLGSCPGRLMGLSHDGALRVLLSGREQVLHSCSL
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHEECCCCCEEEEEECCHHHHHHHCCC
SPIS
CCCC
>Mature Secondary Structure
MNEVVMSFPVYILSKLQGCSMRPLAPEALGGAHALWQRDVRLLPAFEPCRNEVYEGYATS
CCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHCHHCCCCCHHHHHHHHCCCCCC
GGPGCGAVFICDGVGSSLDAAHALHAAGELPVWTSVLAVSQQSGRGQMRRQWVSPAGNIY
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEE
AALRFPAASNYPDSLSSLVAGYVFARAFEMCGIDVRMKWPNDLLLDDCKMAGILLEDRNG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHEEEEEECCCC
ALLVGIGINVAHFPRADCLREGAAVPACGLAARGFDFAPFELWRQLVDRAFFCYRNEVLR
EEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FSEDGLISRLEAYLAWVGRVVMIHGSDLGSCPGRLMGLSHDGALRVLLSGREQVLHSCSL
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHEECCCCCEEEEEECCHHHHHHHCCC
SPIS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]