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The map label for this gene is virA [H]

Identifier: 78356308

GI number: 78356308

Start: 1275533

End: 1277497

Strand: Reverse

Name: virA [H]

Synonym: Dde_1261

Alternate gene names: 78356308

Gene position: 1277497-1275533 (Counterclockwise)

Preceding gene: 78356311

Following gene: 78356307

Centisome position: 34.25

GC content: 57.3

Gene sequence:

>1965_bases
GTGCTTGCTCCCGGGGTTGCCTGCCGGTGGTACCGGCGGGAGGAGGTCGTATTGCGCGCCAATGCCAGCATTGCAGGCCG
TATCGGTCTTTTGCTGCTCTTTCTTATTGTCTTCGCCTCTGCCATCGGACTCACATACACCTACTACATCAAGCTTGTGC
AGTCCGATTCGCTGGCAGAGGTAAAATCGGCCACGGTGCACGGCTACGAACGAACTCTGCGCTACTCGGTGCAAAGCATG
GCCGCGGCATTGTCGGACGCCATGACCAAAGCCCGTGAACGGGGCGATAATCCGGTTGATGTGCTGCGGCGCACCATCAA
TGCCGTGCGCTACGACAACGATGGTTATTACTTTGTCTACGACCTCAACGGCATCAACATCGTCCATCCTCTTGACCCCG
CTTTTCAAGGCACCGACCGCCTGAACCACCACGACAAAGACGGCGTGCCCTACATCAGTATTCTGGCATCACTGGTCCGC
AGCGGCGGCGGTTATGTTTCGTACAGCTTTCACAAGCCCGGCGAAACCACCCCGCTGCCCAAACTGGCCTACGCCGAGAT
TATTCCCGGTACCGACTTCTGGCTGGCCACAGGCATCTACACCGACAACATCCAGAACGAACAGGAAAAGCTGGCCGCGC
GTCTTGACGGGCATATCAACAAGGCCCTGATGATCGTGGGCGTGGGGGTTTTCATCACCCTTGTCTTTTTTGTACTGCCC
ACCAGCCTGTATATGGTCAGCGGCATTCTTAAACCGTGGCGCCAGATGGAACGCGAACTGCGTCATGCACAAAAAATGGA
GGCCATCGGCATTTTTGCTGGCGGCATAGCGCATGATTTCAATAATATTCTCGGTGCCATATCGTCATGCAGCGAACTGG
CACTGGAAGATACGCCGGAAGACAGCCCCGTGCGCGAAGACCTGTACCATGTGCTCAAGGCGGCACGGCGGGGTAAAAAT
CTTGTCAAACGCATCAAGACGTTCAGCCAGCGCACCGAACTGACCAAAACCACGGTGCAGGTACGATACACCGTACAGGA
ATGCATCCAGCTGCTGCAGACATTCATTCCCGCCACAGTGGAGGTCCGCCTGCGCATCAATGCGCCCACCGCGCAGGTAA
AAGCCGACCCGGACCAGCTGCTGCAGGTGCTCATGAACCTGTGCACCAACGCCGAGCAGGCCATGCGCGGCATGAAAGGC
CTGCTGGAAATCACACTGGACATGGAAACTCTGGACACCGGACACGCCGCCCCGCTGGAACTGCCCGCGGGACGTTATGT
GGTCATATCCGTACGCGACACGGGTACAGGCATGAAGCCGGTGGTCATGAAACACGTGTTTGAACCTTTCTACACCACAC
GCAAAAAAAGCGGCGGAACGGGGCTGGGACTTTCCATCACCCAAAACATCGTCCGGCTGCACGGCGGGCGCATAACGGTG
GACAGCGCGCCCAGCAGGGGCTCAACCTTCCGCGTGTACCTGCCCTGCAGCGGCATGGCCGAAGAAGTACAGGAAAAACA
GATACGTTCCGCACTGCAGCGCGGCAATGAATCGTTGCTGATAGTGGATGACGACGATGACCTGGCCTATTCCGTGGGAA
AACTGTTCACGCGGCTGGGATACAAAGTCACCAGCGTCACACGCAGCAAAGAGGCACTGGAACTTTTCAGACGAAAGCCC
CATGCCTTTGATCTGGTACTTACCGACCAGATGATGCCCAACCTCACAGGCGTGGAACTGACTCGCGAGCTGCTGAGCAT
CCGGCCGGACCTGCCCGTCATCATGTACACCGGCTTTGAAGGCACTGGGAACCTGTCGCGCTATCCCAAAGACTGGCGCA
AGGTCGGGGTGGCGGCCTTTTTCTACAAACCGTTTGATACCGCGGCTCTGAGCGCGGAAATACGCACCCAGCTGGACAAG
CATAAAAAGCACAGGAGCACCGCACATGCGCGTTCTGATCATTGA

Upstream 100 bases:

>100_bases
TTGCACCTTTATCCTGAAGTGTGTACGGATAAATCATCGGAAAAGCGCTGCGGTTGCGTCTGCCTGCTGATCAGACGGCG
CTGCTGCCCCCTGTTCCGCA

Downstream 100 bases:

>100_bases
CGACGACGAACATATGCGCCACGCGCTGGGACGCACAGTCAGACGTCTGGGATGTGAACCGGTCATGGCCGGCATGGGCG
GCGAAGGCCTGCAACATGCG

Product: periplasmic sensor hybrid histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MLAPGVACRWYRREEVVLRANASIAGRIGLLLLFLIVFASAIGLTYTYYIKLVQSDSLAEVKSATVHGYERTLRYSVQSM
AAALSDAMTKARERGDNPVDVLRRTINAVRYDNDGYYFVYDLNGINIVHPLDPAFQGTDRLNHHDKDGVPYISILASLVR
SGGGYVSYSFHKPGETTPLPKLAYAEIIPGTDFWLATGIYTDNIQNEQEKLAARLDGHINKALMIVGVGVFITLVFFVLP
TSLYMVSGILKPWRQMERELRHAQKMEAIGIFAGGIAHDFNNILGAISSCSELALEDTPEDSPVREDLYHVLKAARRGKN
LVKRIKTFSQRTELTKTTVQVRYTVQECIQLLQTFIPATVEVRLRINAPTAQVKADPDQLLQVLMNLCTNAEQAMRGMKG
LLEITLDMETLDTGHAAPLELPAGRYVVISVRDTGTGMKPVVMKHVFEPFYTTRKKSGGTGLGLSITQNIVRLHGGRITV
DSAPSRGSTFRVYLPCSGMAEEVQEKQIRSALQRGNESLLIVDDDDDLAYSVGKLFTRLGYKVTSVTRSKEALELFRRKP
HAFDLVLTDQMMPNLTGVELTRELLSIRPDLPVIMYTGFEGTGNLSRYPKDWRKVGVAAFFYKPFDTAALSAEIRTQLDK
HKKHRSTAHARSDH

Sequences:

>Translated_654_residues
MLAPGVACRWYRREEVVLRANASIAGRIGLLLLFLIVFASAIGLTYTYYIKLVQSDSLAEVKSATVHGYERTLRYSVQSM
AAALSDAMTKARERGDNPVDVLRRTINAVRYDNDGYYFVYDLNGINIVHPLDPAFQGTDRLNHHDKDGVPYISILASLVR
SGGGYVSYSFHKPGETTPLPKLAYAEIIPGTDFWLATGIYTDNIQNEQEKLAARLDGHINKALMIVGVGVFITLVFFVLP
TSLYMVSGILKPWRQMERELRHAQKMEAIGIFAGGIAHDFNNILGAISSCSELALEDTPEDSPVREDLYHVLKAARRGKN
LVKRIKTFSQRTELTKTTVQVRYTVQECIQLLQTFIPATVEVRLRINAPTAQVKADPDQLLQVLMNLCTNAEQAMRGMKG
LLEITLDMETLDTGHAAPLELPAGRYVVISVRDTGTGMKPVVMKHVFEPFYTTRKKSGGTGLGLSITQNIVRLHGGRITV
DSAPSRGSTFRVYLPCSGMAEEVQEKQIRSALQRGNESLLIVDDDDDLAYSVGKLFTRLGYKVTSVTRSKEALELFRRKP
HAFDLVLTDQMMPNLTGVELTRELLSIRPDLPVIMYTGFEGTGNLSRYPKDWRKVGVAAFFYKPFDTAALSAEIRTQLDK
HKKHRSTAHARSDH
>Mature_654_residues
MLAPGVACRWYRREEVVLRANASIAGRIGLLLLFLIVFASAIGLTYTYYIKLVQSDSLAEVKSATVHGYERTLRYSVQSM
AAALSDAMTKARERGDNPVDVLRRTINAVRYDNDGYYFVYDLNGINIVHPLDPAFQGTDRLNHHDKDGVPYISILASLVR
SGGGYVSYSFHKPGETTPLPKLAYAEIIPGTDFWLATGIYTDNIQNEQEKLAARLDGHINKALMIVGVGVFITLVFFVLP
TSLYMVSGILKPWRQMERELRHAQKMEAIGIFAGGIAHDFNNILGAISSCSELALEDTPEDSPVREDLYHVLKAARRGKN
LVKRIKTFSQRTELTKTTVQVRYTVQECIQLLQTFIPATVEVRLRINAPTAQVKADPDQLLQVLMNLCTNAEQAMRGMKG
LLEITLDMETLDTGHAAPLELPAGRYVVISVRDTGTGMKPVVMKHVFEPFYTTRKKSGGTGLGLSITQNIVRLHGGRITV
DSAPSRGSTFRVYLPCSGMAEEVQEKQIRSALQRGNESLLIVDDDDDLAYSVGKLFTRLGYKVTSVTRSKEALELFRRKP
HAFDLVLTDQMMPNLTGVELTRELLSIRPDLPVIMYTGFEGTGNLSRYPKDWRKVGVAAFFYKPFDTAALSAEIRTQLDK
HKKHRSTAHARSDH

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=272, Percent_Identity=29.7794117647059, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994928, Length=283, Percent_Identity=27.5618374558304, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790300, Length=313, Percent_Identity=28.7539936102236, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87081816, Length=341, Percent_Identity=23.1671554252199, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=28.8888888888889, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=146, Percent_Identity=32.8767123287671, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72964; Mature: 72964

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPGVACRWYRREEVVLRANASIAGRIGLLLLFLIVFASAIGLTYTYYIKLVQSDSLAE
CCCCCCHHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEHEEEECCCCHHH
VKSATVHGYERTLRYSVQSMAAALSDAMTKARERGDNPVDVLRRTINAVRYDNDGYYFVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCEEEEE
DLNGINIVHPLDPAFQGTDRLNHHDKDGVPYISILASLVRSGGGYVSYSFHKPGETTPLP
ECCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
KLAYAEIIPGTDFWLATGIYTDNIQNEQEKLAARLDGHINKALMIVGVGVFITLVFFVLP
CHHHHHHCCCCCCEEEECEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSLYMVSGILKPWRQMERELRHAQKMEAIGIFAGGIAHDFNNILGAISSCSELALEDTPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DSPVREDLYHVLKAARRGKNLVKRIKTFSQRTELTKTTVQVRYTVQECIQLLQTFIPATV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCEE
EVRLRINAPTAQVKADPDQLLQVLMNLCTNAEQAMRGMKGLLEITLDMETLDTGHAAPLE
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEHHHCCCCCCCCCC
LPAGRYVVISVRDTGTGMKPVVMKHVFEPFYTTRKKSGGTGLGLSITQNIVRLHGGRITV
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
DSAPSRGSTFRVYLPCSGMAEEVQEKQIRSALQRGNESLLIVDDDDDLAYSVGKLFTRLG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC
YKVTSVTRSKEALELFRRKPHAFDLVLTDQMMPNLTGVELTRELLSIRPDLPVIMYTGFE
CCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCC
GTGNLSRYPKDWRKVGVAAFFYKPFDTAALSAEIRTQLDKHKKHRSTAHARSDH
CCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAPGVACRWYRREEVVLRANASIAGRIGLLLLFLIVFASAIGLTYTYYIKLVQSDSLAE
CCCCCCHHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEHEEEECCCCHHH
VKSATVHGYERTLRYSVQSMAAALSDAMTKARERGDNPVDVLRRTINAVRYDNDGYYFVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCEEEEE
DLNGINIVHPLDPAFQGTDRLNHHDKDGVPYISILASLVRSGGGYVSYSFHKPGETTPLP
ECCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
KLAYAEIIPGTDFWLATGIYTDNIQNEQEKLAARLDGHINKALMIVGVGVFITLVFFVLP
CHHHHHHCCCCCCEEEECEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSLYMVSGILKPWRQMERELRHAQKMEAIGIFAGGIAHDFNNILGAISSCSELALEDTPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DSPVREDLYHVLKAARRGKNLVKRIKTFSQRTELTKTTVQVRYTVQECIQLLQTFIPATV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCEE
EVRLRINAPTAQVKADPDQLLQVLMNLCTNAEQAMRGMKGLLEITLDMETLDTGHAAPLE
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEHHHCCCCCCCCCC
LPAGRYVVISVRDTGTGMKPVVMKHVFEPFYTTRKKSGGTGLGLSITQNIVRLHGGRITV
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
DSAPSRGSTFRVYLPCSGMAEEVQEKQIRSALQRGNESLLIVDDDDDLAYSVGKLFTRLG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC
YKVTSVTRSKEALELFRRKPHAFDLVLTDQMMPNLTGVELTRELLSIRPDLPVIMYTGFE
CCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCC
GTGNLSRYPKDWRKVGVAAFFYKPFDTAALSAEIRTQLDKHKKHRSTAHARSDH
CCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]