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The map label for this gene is virA [H]

Identifier: 78356062

GI number: 78356062

Start: 1038169

End: 1039230

Strand: Direct

Name: virA [H]

Synonym: Dde_1015

Alternate gene names: 78356062

Gene position: 1038169-1039230 (Clockwise)

Preceding gene: 78356061

Following gene: 78356063

Centisome position: 27.83

GC content: 64.31

Gene sequence:

>1062_bases
ATGACAGAGCTTTTGCATCACCGGCAGCCGCGGCGCTGCAATGCCGGCCCGCTGTATGCCGTGACAGATAGTGACGGGGT
GTTTGTGGTTGTTTCTGCCGGTTTTGCCTCGCTGATGCACGGTGCCGGTGGGATGCCCGATGCTGCGCTGACGGGACGCC
CCGCAGCAGCTTTTTTGGCGCGCCTGACCCCGGCCCCGCAGATGCCCCTGACAGCGGCCTGGAACGGTAAGGTGTGGCTG
GATTTTTACGGGCTGCTGCATGTGGAGATTGTGCCTTTCACTGCGTGCGCCTGCAAAGAGGGCAGGGCGGCGTGGCATCT
CATACAGTTGCTGCCTGATGCCGCAGAGGCGTGCATGGACTGTGCGGGCAGAACAGCCCGCGGGCTGGCGCACGATTTCA
ACAACGCTCTTGCCTCTGTCATGGGCTTTGCGGAACTGGCAGCCGGACAGGCAGGGCACGGCGGCAGCAGTGAATTGCTG
CACCGCAGTCTGGCCAATGTGCTTAAAGGCTGCGGACGAGCCGGTGCCGTGCTGGAAAAAGCCCGCGCCGTGGCGGGACG
CATCCCGCTGAATCTTACGCGGCATAGCGCCTGCGCACTGCTGCAGCAGTGGACAGACACGAGACGGGCCGCTCTGCCGG
ACTCGGTGCAGCTGTGCACCGGCACGTTGCAGGCGCTGCCCGCCATTACGGCTGATGCCCGCTGGCTTGAAAAAGCTTTT
GCCGCCGTATGGGACAATGCGCTTATGGCCATGCGCGGCACCGGCGGAACCCTGCGCGTGGAATGCCGTGCAGGGCAGGG
GTACGACGGCAGGGCGTATGTGTTTATGGATGTGACCGATACCGGATGCGGCATGGATATGCAGACATGCCGCGAGGCCG
TGGAGCCGTTCTTTTCCGGCTGGGAAAATACAGCGGGGCAGACTTCCGCCGGAGGACAGGGCTGGGGGCTTTCACTGGCG
TGGGGAGTTCTGCGTGCGCACGGCGGCGGACTGGAGATTTCTGCACAGCCGCTGGCCGGATGCCGGGTTTCGTTCCGTCT
GCCTGCTGCGTGCGAGGGCTGA

Upstream 100 bases:

>100_bases
TCGGCAAAGCCAAGGCAGCCGTCATCCACGAGGGGCTTAAAAGGCTTGTGGGTTGAGTCCGCCGGCGGGTGTCTGTTCCT
GCCGGAAACAGGGGAAAGGT

Downstream 100 bases:

>100_bases
GGCTGGTCCGCCGGCGGTACGTGGTCTTTTTTTTGAGGAGGGGACATGGCCCGTGTGCTGATAATAGATGATGATGACCT
GTTTTGCGAAATGGTCGCGG

Product: histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTELLHHRQPRRCNAGPLYAVTDSDGVFVVVSAGFASLMHGAGGMPDAALTGRPAAAFLARLTPAPQMPLTAAWNGKVWL
DFYGLLHVEIVPFTACACKEGRAAWHLIQLLPDAAEACMDCAGRTARGLAHDFNNALASVMGFAELAAGQAGHGGSSELL
HRSLANVLKGCGRAGAVLEKARAVAGRIPLNLTRHSACALLQQWTDTRRAALPDSVQLCTGTLQALPAITADARWLEKAF
AAVWDNALMAMRGTGGTLRVECRAGQGYDGRAYVFMDVTDTGCGMDMQTCREAVEPFFSGWENTAGQTSAGGQGWGLSLA
WGVLRAHGGGLEISAQPLAGCRVSFRLPAACEG

Sequences:

>Translated_353_residues
MTELLHHRQPRRCNAGPLYAVTDSDGVFVVVSAGFASLMHGAGGMPDAALTGRPAAAFLARLTPAPQMPLTAAWNGKVWL
DFYGLLHVEIVPFTACACKEGRAAWHLIQLLPDAAEACMDCAGRTARGLAHDFNNALASVMGFAELAAGQAGHGGSSELL
HRSLANVLKGCGRAGAVLEKARAVAGRIPLNLTRHSACALLQQWTDTRRAALPDSVQLCTGTLQALPAITADARWLEKAF
AAVWDNALMAMRGTGGTLRVECRAGQGYDGRAYVFMDVTDTGCGMDMQTCREAVEPFFSGWENTAGQTSAGGQGWGLSLA
WGVLRAHGGGLEISAQPLAGCRVSFRLPAACEG
>Mature_352_residues
TELLHHRQPRRCNAGPLYAVTDSDGVFVVVSAGFASLMHGAGGMPDAALTGRPAAAFLARLTPAPQMPLTAAWNGKVWLD
FYGLLHVEIVPFTACACKEGRAAWHLIQLLPDAAEACMDCAGRTARGLAHDFNNALASVMGFAELAAGQAGHGGSSELLH
RSLANVLKGCGRAGAVLEKARAVAGRIPLNLTRHSACALLQQWTDTRRAALPDSVQLCTGTLQALPAITADARWLEKAFA
AVWDNALMAMRGTGGTLRVECRAGQGYDGRAYVFMDVTDTGCGMDMQTCREAVEPFFSGWENTAGQTSAGGQGWGLSLAW
GVLRAHGGGLEISAQPLAGCRVSFRLPAACEG

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=26.2096774193548, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37091; Mature: 36960

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELLHHRQPRRCNAGPLYAVTDSDGVFVVVSAGFASLMHGAGGMPDAALTGRPAAAFLA
CCCCHHCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHH
RLTPAPQMPLTAAWNGKVWLDFYGLLHVEIVPFTACACKEGRAAWHLIQLLPDAAEACMD
HCCCCCCCCEEEECCCEEEEEEECEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHH
CAGRTARGLAHDFNNALASVMGFAELAAGQAGHGGSSELLHRSLANVLKGCGRAGAVLEK
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ARAVAGRIPLNLTRHSACALLQQWTDTRRAALPDSVQLCTGTLQALPAITADARWLEKAF
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVWDNALMAMRGTGGTLRVECRAGQGYDGRAYVFMDVTDTGCGMDMQTCREAVEPFFSG
HHHHHHHHEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
WENTAGQTSAGGQGWGLSLAWGVLRAHGGGLEISAQPLAGCRVSFRLPAACEG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TELLHHRQPRRCNAGPLYAVTDSDGVFVVVSAGFASLMHGAGGMPDAALTGRPAAAFLA
CCCHHCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHH
RLTPAPQMPLTAAWNGKVWLDFYGLLHVEIVPFTACACKEGRAAWHLIQLLPDAAEACMD
HCCCCCCCCEEEECCCEEEEEEECEEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHH
CAGRTARGLAHDFNNALASVMGFAELAAGQAGHGGSSELLHRSLANVLKGCGRAGAVLEK
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ARAVAGRIPLNLTRHSACALLQQWTDTRRAALPDSVQLCTGTLQALPAITADARWLEKAF
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVWDNALMAMRGTGGTLRVECRAGQGYDGRAYVFMDVTDTGCGMDMQTCREAVEPFFSG
HHHHHHHHEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
WENTAGQTSAGGQGWGLSLAWGVLRAHGGGLEISAQPLAGCRVSFRLPAACEG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]