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The map label for this gene is zraR [H]

Identifier: 78355156

GI number: 78355156

Start: 100305

End: 101705

Strand: Reverse

Name: zraR [H]

Synonym: Dde_0109

Alternate gene names: 78355156

Gene position: 101705-100305 (Counterclockwise)

Preceding gene: 78355157

Following gene: 78355153

Centisome position: 2.73

GC content: 59.89

Gene sequence:

>1401_bases
ATGACAAACGCTCCTACCATATTGATAGTGGATGATGATCAGGCGCACAGAACCATGCTGCGCACCATGCTGCGCGGCTG
GCAGTACTCGGCGGAAGAAGCCGACGACGGTTCCGTGGCCGTGAGCAAGGTGCAGGAGCGCGCATATGACGCCATCCTGA
TGGATATCCGCATGGCCCGCATGAGCGGCATAGAAGCCCTGCGGCATATCATGGCCCACAATCCGGCCATTCCCGTGCTT
ATCATGACGGCATATTCTTCGGTGAATACAGCGGTGGAAGCCCTGAAAATAGGTGCTTATGACTACCTGACAAAGCCGCT
TGATTTCGACGAGCTGAAACTGACGCTGGAGCGCGCGCTTGATCACACGCGGCTGGCCTCGGAAAACAGAGAGCTGCGCA
GCTCTCTGTCCGCGGGGCAGGCTGCCTCGCGCATTATCGGCCGCAGCGAGGCCGTGCGCCGGCTTACCGAGCTGGTGGCC
ACAGTGGCGCCCAGCGACGCCACGGTACTCATCACCGGAGAATCGGGCACAGGCAAAGAACTGGTGGCCAGAGCCATACA
CGAAGGAAGCAGCAGACGTGACAGACCGCTGGTAACCGTCAACTGCGCCGCCCTTACGGAATCGCTGCTGGAATCAGAAC
TGTTCGGCCACGAAAAAGGTGCTTTTACCGGTGCGGACAAAAAACGCGACGGGCGGTTTGTTCAGGCGGACGGCGGTACG
TTGTTTCTGGATGAACTGGGCGAAATGTCTCTGGCACTGCAGGCAAAGCTGCTGCGTGCGCTGCAGCAGGGTGAAATCCA
GAGGGTGGGCAGCGACAACCCGCTGAGAGTCGATGTACGCGTCATCGCCGCAACCAACCGCAATCTGACCGCAGAGGTGA
CCGCAGGCAGGTTCCGCGAAGACCTGTTTTACCGGCTCAACGTCATCGGCATAGCGGTACCGGCACTGCGGGAACGGCGC
GACGACATCCCCCTGCTGGCCGGACACTTTCTGACCCGCTATGCCGAACGTAACCGCAAGATGCTCAAAGGATTCACCCC
GCAGGCCATGAACTGTCTGGTCAACTATGACTGGCCGGGCAATGTGCGTGAACTGGAAAACGCCGTGGAGCGCGCCGTTA
TCATGAGCATGGGCGAATATGTCACCGGACGCGAACTGCCGCCGGACATTGCAGCGGCTGACGGCGAAACGGATATCACC
GCAGCAGTGCCCGATACGGACACACCGCTGCCCGACACCGTCCATGACCCCTATGCGGGGCTCTCGCTGGAAAATCTGGA
ACGCCGCGCCATTGAGGCAACGCTGCGCGAATGTGCCGACAATAAAAGCGAAGCCGCCCGCCGGCTGGGCATCACCCGCG
CAACACTGCACAACAAGCTGAAAAAATACGGCATGGAATAA

Upstream 100 bases:

>100_bases
AGTCTTCCGTAGGCAGCGGAACGGAAATATCTCTCATTCTGCCGCTTGAACCGCAACGCAACGCGAACAGCTGACCCGGC
GGCGCGTCAAAGGAACAGCC

Downstream 100 bases:

>100_bases
CCGGAAGGCCGGAACCGGAACAAGACCTCCGGCGGGCAAGAGGCATGATTCCCCCTGCATCCCCCGTTGCGCATGTTCTG
CCGCGGTCAGCTGACATCGA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTNAPTILIVDDDQAHRTMLRTMLRGWQYSAEEADDGSVAVSKVQERAYDAILMDIRMARMSGIEALRHIMAHNPAIPVL
IMTAYSSVNTAVEALKIGAYDYLTKPLDFDELKLTLERALDHTRLASENRELRSSLSAGQAASRIIGRSEAVRRLTELVA
TVAPSDATVLITGESGTGKELVARAIHEGSSRRDRPLVTVNCAALTESLLESELFGHEKGAFTGADKKRDGRFVQADGGT
LFLDELGEMSLALQAKLLRALQQGEIQRVGSDNPLRVDVRVIAATNRNLTAEVTAGRFREDLFYRLNVIGIAVPALRERR
DDIPLLAGHFLTRYAERNRKMLKGFTPQAMNCLVNYDWPGNVRELENAVERAVIMSMGEYVTGRELPPDIAAADGETDIT
AAVPDTDTPLPDTVHDPYAGLSLENLERRAIEATLRECADNKSEAARRLGITRATLHNKLKKYGME

Sequences:

>Translated_466_residues
MTNAPTILIVDDDQAHRTMLRTMLRGWQYSAEEADDGSVAVSKVQERAYDAILMDIRMARMSGIEALRHIMAHNPAIPVL
IMTAYSSVNTAVEALKIGAYDYLTKPLDFDELKLTLERALDHTRLASENRELRSSLSAGQAASRIIGRSEAVRRLTELVA
TVAPSDATVLITGESGTGKELVARAIHEGSSRRDRPLVTVNCAALTESLLESELFGHEKGAFTGADKKRDGRFVQADGGT
LFLDELGEMSLALQAKLLRALQQGEIQRVGSDNPLRVDVRVIAATNRNLTAEVTAGRFREDLFYRLNVIGIAVPALRERR
DDIPLLAGHFLTRYAERNRKMLKGFTPQAMNCLVNYDWPGNVRELENAVERAVIMSMGEYVTGRELPPDIAAADGETDIT
AAVPDTDTPLPDTVHDPYAGLSLENLERRAIEATLRECADNKSEAARRLGITRATLHNKLKKYGME
>Mature_465_residues
TNAPTILIVDDDQAHRTMLRTMLRGWQYSAEEADDGSVAVSKVQERAYDAILMDIRMARMSGIEALRHIMAHNPAIPVLI
MTAYSSVNTAVEALKIGAYDYLTKPLDFDELKLTLERALDHTRLASENRELRSSLSAGQAASRIIGRSEAVRRLTELVAT
VAPSDATVLITGESGTGKELVARAIHEGSSRRDRPLVTVNCAALTESLLESELFGHEKGAFTGADKKRDGRFVQADGGTL
FLDELGEMSLALQAKLLRALQQGEIQRVGSDNPLRVDVRVIAATNRNLTAEVTAGRFREDLFYRLNVIGIAVPALRERRD
DIPLLAGHFLTRYAERNRKMLKGFTPQAMNCLVNYDWPGNVRELENAVERAVIMSMGEYVTGRELPPDIAAADGETDITA
AVPDTDTPLPDTVHDPYAGLSLENLERRAIEATLRECADNKSEAARRLGITRATLHNKLKKYGME

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=456, Percent_Identity=59.6491228070175, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1788550, Length=466, Percent_Identity=46.3519313304721, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1790299, Length=468, Percent_Identity=41.8803418803419, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1788905, Length=467, Percent_Identity=37.4732334047109, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI87082117, Length=350, Percent_Identity=46, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI87082152, Length=328, Percent_Identity=49.6951219512195, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=45.0617283950617, Blast_Score=276, Evalue=3e-75,
Organism=Escherichia coli, GI1789087, Length=347, Percent_Identity=46.685878962536, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI87081872, Length=325, Percent_Identity=42.4615384615385, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1786524, Length=365, Percent_Identity=39.4520547945205, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1787583, Length=328, Percent_Identity=39.0243902439024, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789828, Length=270, Percent_Identity=35.1851851851852, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87081858, Length=314, Percent_Identity=31.8471337579618, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1786911, Length=187, Percent_Identity=31.5508021390374, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=117, Percent_Identity=34.1880341880342, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=127, Percent_Identity=33.0708661417323, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790860, Length=102, Percent_Identity=32.3529411764706, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788191, Length=104, Percent_Identity=34.6153846153846, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51379; Mature: 51248

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAPTILIVDDDQAHRTMLRTMLRGWQYSAEEADDGSVAVSKVQERAYDAILMDIRMAR
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MSGIEALRHIMAHNPAIPVLIMTAYSSVNTAVEALKIGAYDYLTKPLDFDELKLTLERAL
HHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHH
DHTRLASENRELRSSLSAGQAASRIIGRSEAVRRLTELVATVAPSDATVLITGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
LVARAIHEGSSRRDRPLVTVNCAALTESLLESELFGHEKGAFTGADKKRDGRFVQADGGT
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCE
LFLDELGEMSLALQAKLLRALQQGEIQRVGSDNPLRVDVRVIAATNRNLTAEVTAGRFRE
EEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHH
DLFYRLNVIGIAVPALRERRDDIPLLAGHFLTRYAERNRKMLKGFTPQAMNCLVNYDWPG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCC
NVRELENAVERAVIMSMGEYVTGRELPPDIAAADGETDITAAVPDTDTPLPDTVHDPYAG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
LSLENLERRAIEATLRECADNKSEAARRLGITRATLHNKLKKYGME
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNAPTILIVDDDQAHRTMLRTMLRGWQYSAEEADDGSVAVSKVQERAYDAILMDIRMAR
CCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MSGIEALRHIMAHNPAIPVLIMTAYSSVNTAVEALKIGAYDYLTKPLDFDELKLTLERAL
HHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHH
DHTRLASENRELRSSLSAGQAASRIIGRSEAVRRLTELVATVAPSDATVLITGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
LVARAIHEGSSRRDRPLVTVNCAALTESLLESELFGHEKGAFTGADKKRDGRFVQADGGT
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCE
LFLDELGEMSLALQAKLLRALQQGEIQRVGSDNPLRVDVRVIAATNRNLTAEVTAGRFRE
EEHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEEEEEECCCCEEEEEHHHHHHH
DLFYRLNVIGIAVPALRERRDDIPLLAGHFLTRYAERNRKMLKGFTPQAMNCLVNYDWPG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCC
NVRELENAVERAVIMSMGEYVTGRELPPDIAAADGETDITAAVPDTDTPLPDTVHDPYAG
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
LSLENLERRAIEATLRECADNKSEAARRLGITRATLHNKLKKYGME
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]