| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome, complete genome. |
|---|---|
| Accession | NC_007519 |
| Length | 3,730,232 |
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The map label for this gene is gyrB [H]
Identifier: 78355050
GI number: 78355050
Start: 2797
End: 5190
Strand: Direct
Name: gyrB [H]
Synonym: Dde_0003
Alternate gene names: 78355050
Gene position: 2797-5190 (Clockwise)
Preceding gene: 78355049
Following gene: 78355051
Centisome position: 0.07
GC content: 55.1
Gene sequence:
>2394_bases ATGACCAACGAGACACAAAAGCAGAGCTACGACGCGGCGAACATCACCGTTCTTGAGGGGTTGTCCGCTGTGCGCATGCG CCCTGCCATGTACATAGGCAGCACTGACAGCCGCGGTCTGCACCATCTGGTTTACGAAGTGGTGGATAACTCCATCGACG AAGCCATGGCGGGATACTGCGATAAAGTCACCGTGAAGCTGCATCTTGATAACAGCGTGACCGTTATTGATAACGGACGC GGCATTCCCGTGGACATCCACCCGAAAGAAGGCCGTCCCGCGGTTGAAGTGGTCATGACCGTGCTGCATGCCGGCGGCAA GTTCGACAACGATTCGTACAAGGTGTCGGGCGGGCTGCACGGGGTGGGTGTTTCGTGCGTGAACGCCCTTTCCGAATATC TCGAAGTTACCGTGCGTCGTGACGGGTATAAATATCATCACCGCTTTGAACGCGGTGTACCGGTCAAGGAACTGGAGCGC GTCGGAGAAACCGACCTGCGCGGCACCACCATCCGCTTCCGTCCGGACGAAGAAATTTTTGAGACCAATCAGTTTTCCTT CGATATCCTCAAAAAACGCTTTGAGGAGCTCGCGTACCTCAATCCCGGGCTCGAGGTCGAGTTCATAGACGAACGTACCG GAGATACCGCCTCGTTTCATTACGAGGGGGGTATCCGTGAGTTTGTGAAGAACCTGAACTCCGGCGAAGGCGGGGTGCAC TCCATCATTTTCGCTTCGGGCGAATCGGATAACGTGATGGTGGATTTCGCGTTGCAGTACAACGCGGGGTATAAGGAAAA CATGCTCACCTTTGCCAACAACATCCGCACCAAGGAAGGCGGCACGCACCTTGCCGGCTTCAAGACCGCGCTCACAAGGG CCATCAACAACTACATCCAGAACTCCGACCTGCCTAAAAAGCTCAAGGTCAAACTGTCGGGTGATGATGTGCGGGAAGGT CTGACCGGCGTTGTCAGTGTTAAACTGCCCAATCCGCAGTTTGAAGGGCAGACAAAGACCAAGCTGGGCAACAGCGAGGT GGCGGGTATTGTCTCCGGTCTGGTGTATGAAAATCTCAACACCTACTTCGGCGAAAACCCCAAAGATGCCAAGCTGATCA TAGAAAAGGCCGTGGATGCCGCCCGTGCACGTGACGCCGCCCGCAAGGCGAAGGATCTTGTACGGCGCAAAGGGGCGCTT TCCGACAATGCCCTGCCCGGCAAGCTGGCTGACTGCCAGAGCAAGGATCCCTCGGAATCCGAACTGTTCATCGTGGAAGG TGACTCCGCAGGCGGTTCTGCAAAACAGGGGCGCAATCCTTCCACTCAGGCCATTCTGCCGTTGCGCGGTAAAATTCTGA ACGTGGAAAAGACCCGCTTTGACAAGATGCTGGCCAACAAGGAAGTCAAGGCTCTCATCACGGCCATGGGGGCGGGAATA GGCGAAGAAGACATCGACTACGGCAAGCTGCGGTACCACAAAATCGTCATCATGACCGACGCCGACGTGGACGGTGCCCA CATACGCACGCTGCTGCTGACGTTCTTCTATCGCCAGTATCCCGAGCTGATAGACAGGGGGCACCTGTATATCGCCCAGC CGCCGCTTTTCCGTGTGTACAACAGCAAGTTCGAGCGGTTTATCAAAGATGAAACCGAGCTGAACACCTATCTGCTGGAA CGCATTGCCAAAGACGTCGTCATCGAGGCGCATAACGGCATGGAGTTCCGTGAAACGCAGATACTCGACCTGCTGAAAGC CATACGGTTCATCAATGCCAGAATTGCCGACGTGGAAAACGTGGGAATAGGCCGTAATCTCTTTCTCGCGTTTCTTGAAT ACGGCGAAAAACTGTCGCCCCAGTTTTTTGAGGCGCCTGAATTCAACGGCTTCGGAACGTATCTGCAGGAAAAAGGCTAT TCCGTGCAGACCAGCGTTGACGAATCCGGACTGGAACGCCGTGTGTACCTGGAATTTGAAGACAGCAACGGGCACAAGAC CCGCATCGGCAACGAGTTCTTCAACTCCAAGATGTACAAACAGCCTTACGATTCGATGGCCGACATGCGCCGCATCTGCG GCGGATTCTCGTTTGTGGTGGACCGCAAGGGCGAACGGACCGAAGTGGAAAACATCTTCGTTCTGCTGGACCATGTGCTG CAGGAAGCGCGCAAGGGTATAAACATCCAGCGGTATAAAGGTCTGGGCGAAATGGATGCCGAACAGCTTTGGGTGACCAC CATGAACCCCGAAAACCGCGTGCTGCTGCAGGTACAGGTGGATGACGCGGAAGAGGCCAACGAGATATTTGAACAGCTCA TGGGCGACAGGGTTGAACCGCGCCGCGAATTCATCGTGCGTAATGCCCTGAGCGTTCAGGAACTGGATATTTAA
Upstream 100 bases:
>100_bases CCCCTGCGGTCTGACCGGTGAAAACGACCCCGACTATCTGGTAATCGTCATGCCCATGAAGATAGTGGAAGAGACGTACT ACAGCGAGGAAGAAGTCTAA
Downstream 100 bases:
>100_bases CACACCCGAGAGGCTTCAGAAGTGTCCAATCAGGTTACCATCGAAGACGAGCTTAAGAAGTCATATCTTGAGTACTCGCT GAGTGTTATTATAGGCCGCG
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 797; Mature: 796
Protein sequence:
>797_residues MTNETQKQSYDAANITVLEGLSAVRMRPAMYIGSTDSRGLHHLVYEVVDNSIDEAMAGYCDKVTVKLHLDNSVTVIDNGR GIPVDIHPKEGRPAVEVVMTVLHAGGKFDNDSYKVSGGLHGVGVSCVNALSEYLEVTVRRDGYKYHHRFERGVPVKELER VGETDLRGTTIRFRPDEEIFETNQFSFDILKKRFEELAYLNPGLEVEFIDERTGDTASFHYEGGIREFVKNLNSGEGGVH SIIFASGESDNVMVDFALQYNAGYKENMLTFANNIRTKEGGTHLAGFKTALTRAINNYIQNSDLPKKLKVKLSGDDVREG LTGVVSVKLPNPQFEGQTKTKLGNSEVAGIVSGLVYENLNTYFGENPKDAKLIIEKAVDAARARDAARKAKDLVRRKGAL SDNALPGKLADCQSKDPSESELFIVEGDSAGGSAKQGRNPSTQAILPLRGKILNVEKTRFDKMLANKEVKALITAMGAGI GEEDIDYGKLRYHKIVIMTDADVDGAHIRTLLLTFFYRQYPELIDRGHLYIAQPPLFRVYNSKFERFIKDETELNTYLLE RIAKDVVIEAHNGMEFRETQILDLLKAIRFINARIADVENVGIGRNLFLAFLEYGEKLSPQFFEAPEFNGFGTYLQEKGY SVQTSVDESGLERRVYLEFEDSNGHKTRIGNEFFNSKMYKQPYDSMADMRRICGGFSFVVDRKGERTEVENIFVLLDHVL QEARKGINIQRYKGLGEMDAEQLWVTTMNPENRVLLQVQVDDAEEANEIFEQLMGDRVEPRREFIVRNALSVQELDI
Sequences:
>Translated_797_residues MTNETQKQSYDAANITVLEGLSAVRMRPAMYIGSTDSRGLHHLVYEVVDNSIDEAMAGYCDKVTVKLHLDNSVTVIDNGR GIPVDIHPKEGRPAVEVVMTVLHAGGKFDNDSYKVSGGLHGVGVSCVNALSEYLEVTVRRDGYKYHHRFERGVPVKELER VGETDLRGTTIRFRPDEEIFETNQFSFDILKKRFEELAYLNPGLEVEFIDERTGDTASFHYEGGIREFVKNLNSGEGGVH SIIFASGESDNVMVDFALQYNAGYKENMLTFANNIRTKEGGTHLAGFKTALTRAINNYIQNSDLPKKLKVKLSGDDVREG LTGVVSVKLPNPQFEGQTKTKLGNSEVAGIVSGLVYENLNTYFGENPKDAKLIIEKAVDAARARDAARKAKDLVRRKGAL SDNALPGKLADCQSKDPSESELFIVEGDSAGGSAKQGRNPSTQAILPLRGKILNVEKTRFDKMLANKEVKALITAMGAGI GEEDIDYGKLRYHKIVIMTDADVDGAHIRTLLLTFFYRQYPELIDRGHLYIAQPPLFRVYNSKFERFIKDETELNTYLLE RIAKDVVIEAHNGMEFRETQILDLLKAIRFINARIADVENVGIGRNLFLAFLEYGEKLSPQFFEAPEFNGFGTYLQEKGY SVQTSVDESGLERRVYLEFEDSNGHKTRIGNEFFNSKMYKQPYDSMADMRRICGGFSFVVDRKGERTEVENIFVLLDHVL QEARKGINIQRYKGLGEMDAEQLWVTTMNPENRVLLQVQVDDAEEANEIFEQLMGDRVEPRREFIVRNALSVQELDI >Mature_796_residues TNETQKQSYDAANITVLEGLSAVRMRPAMYIGSTDSRGLHHLVYEVVDNSIDEAMAGYCDKVTVKLHLDNSVTVIDNGRG IPVDIHPKEGRPAVEVVMTVLHAGGKFDNDSYKVSGGLHGVGVSCVNALSEYLEVTVRRDGYKYHHRFERGVPVKELERV GETDLRGTTIRFRPDEEIFETNQFSFDILKKRFEELAYLNPGLEVEFIDERTGDTASFHYEGGIREFVKNLNSGEGGVHS IIFASGESDNVMVDFALQYNAGYKENMLTFANNIRTKEGGTHLAGFKTALTRAINNYIQNSDLPKKLKVKLSGDDVREGL TGVVSVKLPNPQFEGQTKTKLGNSEVAGIVSGLVYENLNTYFGENPKDAKLIIEKAVDAARARDAARKAKDLVRRKGALS DNALPGKLADCQSKDPSESELFIVEGDSAGGSAKQGRNPSTQAILPLRGKILNVEKTRFDKMLANKEVKALITAMGAGIG EEDIDYGKLRYHKIVIMTDADVDGAHIRTLLLTFFYRQYPELIDRGHLYIAQPPLFRVYNSKFERFIKDETELNTYLLER IAKDVVIEAHNGMEFRETQILDLLKAIRFINARIADVENVGIGRNLFLAFLEYGEKLSPQFFEAPEFNGFGTYLQEKGYS VQTSVDESGLERRVYLEFEDSNGHKTRIGNEFFNSKMYKQPYDSMADMRRICGGFSFVVDRKGERTEVENIFVLLDHVLQ EARKGINIQRYKGLGEMDAEQLWVTTMNPENRVLLQVQVDDAEEANEIFEQLMGDRVEPRREFIVRNALSVQELDI
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=574, Percent_Identity=24.9128919860627, Blast_Score=123, Evalue=6e-28, Organism=Homo sapiens, GI19913408, Length=571, Percent_Identity=24.6935201401051, Blast_Score=118, Evalue=2e-26, Organism=Escherichia coli, GI48994957, Length=821, Percent_Identity=48.2338611449452, Blast_Score=722, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=537, Percent_Identity=44.3202979515829, Blast_Score=427, Evalue=1e-120, Organism=Caenorhabditis elegans, GI212645845, Length=505, Percent_Identity=25.3465346534653, Blast_Score=122, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17535065, Length=573, Percent_Identity=24.4328097731239, Blast_Score=119, Evalue=4e-27, Organism=Saccharomyces cerevisiae, GI6324241, Length=580, Percent_Identity=24.4827586206897, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI17136538, Length=550, Percent_Identity=25.6363636363636, Blast_Score=130, Evalue=4e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 89662; Mature: 89530
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNETQKQSYDAANITVLEGLSAVRMRPAMYIGSTDSRGLHHLVYEVVDNSIDEAMAGYC CCCCCHHHCCCCCCEEHHHCCHHHHHCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHCCC DKVTVKLHLDNSVTVIDNGRGIPVDIHPKEGRPAVEVVMTVLHAGGKFDNDSYKVSGGLH CEEEEEEEECCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCC GVGVSCVNALSEYLEVTVRRDGYKYHHRFERGVPVKELERVGETDLRGTTIRFRPDEEIF CHHHHHHHHHHHHHHEEHHCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCHHHH ETNQFSFDILKKRFEELAYLNPGLEVEFIDERTGDTASFHYEGGIREFVKNLNSGEGGVH HCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHCCCCCCCEE SIIFASGESDNVMVDFALQYNAGYKENMLTFANNIRTKEGGTHLAGFKTALTRAINNYIQ EEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC NSDLPKKLKVKLSGDDVREGLTGVVSVKLPNPQFEGQTKTKLGNSEVAGIVSGLVYENLN CCCCCCEEEEEECCCHHHCCCCEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH TYFGENPKDAKLIIEKAVDAARARDAARKAKDLVRRKGALSDNALPGKLADCQSKDPSES HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC ELFIVEGDSAGGSAKQGRNPSTQAILPLRGKILNVEKTRFDKMLANKEVKALITAMGAGI EEEEEECCCCCCCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCC GEEDIDYGKLRYHKIVIMTDADVDGAHIRTLLLTFFYRQYPELIDRGHLYIAQPPLFRVY CCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH NSKFERFIKDETELNTYLLERIAKDVVIEAHNGMEFRETQILDLLKAIRFINARIADVEN HHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC VGIGRNLFLAFLEYGEKLSPQFFEAPEFNGFGTYLQEKGYSVQTSVDESGLERRVYLEFE CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEEEEEEE DSNGHKTRIGNEFFNSKMYKQPYDSMADMRRICGGFSFVVDRKGERTEVENIFVLLDHVL CCCCCCCCCCHHHHHCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHH QEARKGINIQRYKGLGEMDAEQLWVTTMNPENRVLLQVQVDDAEEANEIFEQLMGDRVEP HHHHHCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCCH RREFIVRNALSVQELDI HHHHHHHHCCCHHHCCC >Mature Secondary Structure TNETQKQSYDAANITVLEGLSAVRMRPAMYIGSTDSRGLHHLVYEVVDNSIDEAMAGYC CCCCHHHCCCCCCEEHHHCCHHHHHCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHCCC DKVTVKLHLDNSVTVIDNGRGIPVDIHPKEGRPAVEVVMTVLHAGGKFDNDSYKVSGGLH CEEEEEEEECCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCC GVGVSCVNALSEYLEVTVRRDGYKYHHRFERGVPVKELERVGETDLRGTTIRFRPDEEIF CHHHHHHHHHHHHHHEEHHCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCHHHH ETNQFSFDILKKRFEELAYLNPGLEVEFIDERTGDTASFHYEGGIREFVKNLNSGEGGVH HCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCHHHHHHHCCCCCCCEE SIIFASGESDNVMVDFALQYNAGYKENMLTFANNIRTKEGGTHLAGFKTALTRAINNYIQ EEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC NSDLPKKLKVKLSGDDVREGLTGVVSVKLPNPQFEGQTKTKLGNSEVAGIVSGLVYENLN CCCCCCEEEEEECCCHHHCCCCEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH TYFGENPKDAKLIIEKAVDAARARDAARKAKDLVRRKGALSDNALPGKLADCQSKDPSES HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC ELFIVEGDSAGGSAKQGRNPSTQAILPLRGKILNVEKTRFDKMLANKEVKALITAMGAGI EEEEEECCCCCCCCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCC GEEDIDYGKLRYHKIVIMTDADVDGAHIRTLLLTFFYRQYPELIDRGHLYIAQPPLFRVY CCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH NSKFERFIKDETELNTYLLERIAKDVVIEAHNGMEFRETQILDLLKAIRFINARIADVEN HHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC VGIGRNLFLAFLEYGEKLSPQFFEAPEFNGFGTYLQEKGYSVQTSVDESGLERRVYLEFE CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEEEEEEE DSNGHKTRIGNEFFNSKMYKQPYDSMADMRRICGGFSFVVDRKGERTEVENIFVLLDHVL CCCCCCCCCCHHHHHCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHH QEARKGINIQRYKGLGEMDAEQLWVTTMNPENRVLLQVQVDDAEEANEIFEQLMGDRVEP HHHHHCCCEEECCCCCCCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCCH RREFIVRNALSVQELDI HHHHHHHHCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10688204 [H]