| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome, complete genome. |
|---|---|
| Accession | NC_007519 |
| Length | 3,730,232 |
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The map label for this gene is gyrA [H]
Identifier: 78355051
GI number: 78355051
Start: 5212
End: 7647
Strand: Direct
Name: gyrA [H]
Synonym: Dde_0004
Alternate gene names: 78355051
Gene position: 5212-7647 (Clockwise)
Preceding gene: 78355050
Following gene: 78355052
Centisome position: 0.14
GC content: 55.71
Gene sequence:
>2436_bases GTGTCCAATCAGGTTACCATCGAAGACGAGCTTAAGAAGTCATATCTTGAGTACTCGCTGAGTGTTATTATAGGCCGCGC CATTCCCGATGTGCGCGATGGCCTGAAGCCCGTGCACCGGCGCATCATGTTCGCCCAGCACGAGCTGGGCAACGGGTATA ACCGTGCGCCGAAAAAATCGGCCCGTGTGGTCGGTGACGTTATCGGTAAATACCACCCGCATGGCGATTTCGCCGTGTAC GATGCCCTTGTGCGCATGGCACAGGATTTTTCCATGCGCGACCCGCTTGTCACCGGTCAGGGCAACTTCGGTTCCATTGA CGGCGATTCCGCGGCAGCCATGCGTTATACCGAAGTGCGCATGTCGAGACTCGCTTCGGAATTCATGGCCGATATAGACA AGGAAACCGTCGAGTTCCGCCCCAACTATGACAATACCCTGCAGGAACCCGCGGTGCTGCCCACCAAGGTGCCCAACCTG CTGCTTAACGGCTCTTCGGGTATTGCCGTGGGTATGGCCACCAATATTCCGCCGCACAACCTCGGCGAACTGGTTGACGG CCTGCTGCTGGAACTGGACTCTCCGGAATGCACGGTGGCTGATCTTGCCGGGCTGGTCAAAGGGCCCGACTTTCCCACCG GCGGCTTCTGCTACGCGGGCAGAGGACTGCGCGATGCGTATGAAACAGGACGGGGCACTGTTAAAATCCGCGGCCGTGTG GAAGTGGAAGAACGCAAAAAAGGCTTCCAGTCCATTGTCATCCGCGAAATACCCTATGCGCTGAACAAGTCATCGCTTGT CGAAAAAATAGCCGCGCTGGCCAACGAACGCAGGATAGAAGGCATAACCGACCTGCGTGACGAATCTGACAGACGCGGTA TCCGCGTGGTCATAGACCTGAAGCGCGGCACCATTCCCGAAATCGTCATTAACCAGCTGTATAAATATACTCCGCTGGAG ACGTCTTTCGGCATCAATATGCTGGCTGTGGTGGGCAACAGGCCCCAGCTGCTTACGCTGAAAAAGGTCTTTGAGTGCTT TTTGCAGCACCGGCGCGAAGTCATTATCCGCAGAACACACTATGACCTGCGCAAGGCCGAAGCCCGTGCCCATATTCTGG AAGGTCTGCGTATCGCGCTGGATAACATCGACGAAGTGGTCGAACTTATCCGTGCATCCAAAACACCGCCGGAAGCAAAA GAACGGCTCATGCAGCGGTTCTCGCTTTCCGAAGTGCAGGCTCAGGCCATTCTTGATATGCGTCTGCAGCGTCTTACCAA CCTCGAACACGAAAAACTGATCGAGGAATACCGCGAGCTGCTTAAAAAGATCGAATACTTCAAGTCCATTCTGGAAAATG AAGAAGTGCTGCGCGGCGTTATCCGTGACGAGCTTAAAGAGCTCAAGGAAACATACGCCACCCCGCGGCGGACCGAAATG CTGGAAGATGAACTTGAAGGAATAGACATCGAGGACCTTATTCCCGACGAGGATGTGGTCATCACACTGTCGCGGCGCGG GTACATCAAGCGTACTCCGCTGGACAGCTATCAGCAGCAGCGCCGCGGCGGTAAGGGCATTGCCGGTGTGCATACCGGCG ATGGTGACTTTGTGCAGGATTTTCTGGTGACTACAAACCACCAGTACCTGCTGCTGTTCACCAACAAAGGGCGCATGTTC CAGCTTAAGGTGCATCAGGTGCCCGAAGGCAGTCGTACCGCCAAGGGAATGCACATCAACAACCTGCTGCCCATGGAAGA AAACGAATGGGTGAACACCGCGCTGACTATCCGTGAATTCACGGAAGAAAAGTATTTCCTTTTCTCCACCCGCAAAGGCA TGGTCAAGCGCTCCAGCGCATCGCTGTATGCCAAGGCCCGTCGTACAGGGCTTATTGCCGTGGGGCTGCGTGAAGGAGAT GAGCTTATCATGGTGCGCGAGGTGGATGACAACTGCGAAGTTGTTCTGACCACCGAAAAAGGTATCGCCATACGCTTCGG CTGCGGCGATGTGCGCCCCATGGGGCGTTCCGCTACCGGCGTCAAAGGCATTGCGCTGAGTCAGGACGACAGTGTGGTGG CCTGCGTTACCGTGCAGGGCGGACTGGAATCGGAAATAATGACCGTTTCGCGGTACGGATACGGTAAACGGACACTTATC GATCGGTACCGTGTACAGAGCCGCGGCGGTAAAGGTGTCATCAACTTCAAGGTGACACCCAAGACCGGTGAAGTGCTGGG CGCCATGACCGTAGTATCCAACGACCAGCTGATTCTGCTTACCTCCACCAACAAGATTATCCGCATAGGTGTGAAAGAGG TCCGCAGTGTGGGCCGCGCCACACAGGGCGTGCGTCTTGTCTGGCTGGACGAAGGCGACCATGTGGTCGGCTTTGACAGA GTTTCGGAGCAGGAACAGGAACAGCTTGACGATTAG
Upstream 100 bases:
>100_bases GCTCATGGGCGACAGGGTTGAACCGCGCCGCGAATTCATCGTGCGTAATGCCCTGAGCGTTCAGGAACTGGATATTTAAC ACACCCGAGAGGCTTCAGAA
Downstream 100 bases:
>100_bases GCGGGCATGATGCTGCAAAGGCAGACTGTTGCGCGTTGCGCACTGTGCATTACTGTCATGCTTTGGGCCTTTTTTTCATG GGGCTGCAAAGAAAATGACG
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 811; Mature: 810
Protein sequence:
>811_residues MSNQVTIEDELKKSYLEYSLSVIIGRAIPDVRDGLKPVHRRIMFAQHELGNGYNRAPKKSARVVGDVIGKYHPHGDFAVY DALVRMAQDFSMRDPLVTGQGNFGSIDGDSAAAMRYTEVRMSRLASEFMADIDKETVEFRPNYDNTLQEPAVLPTKVPNL LLNGSSGIAVGMATNIPPHNLGELVDGLLLELDSPECTVADLAGLVKGPDFPTGGFCYAGRGLRDAYETGRGTVKIRGRV EVEERKKGFQSIVIREIPYALNKSSLVEKIAALANERRIEGITDLRDESDRRGIRVVIDLKRGTIPEIVINQLYKYTPLE TSFGINMLAVVGNRPQLLTLKKVFECFLQHRREVIIRRTHYDLRKAEARAHILEGLRIALDNIDEVVELIRASKTPPEAK ERLMQRFSLSEVQAQAILDMRLQRLTNLEHEKLIEEYRELLKKIEYFKSILENEEVLRGVIRDELKELKETYATPRRTEM LEDELEGIDIEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHTGDGDFVQDFLVTTNHQYLLLFTNKGRMF QLKVHQVPEGSRTAKGMHINNLLPMEENEWVNTALTIREFTEEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGD ELIMVREVDDNCEVVLTTEKGIAIRFGCGDVRPMGRSATGVKGIALSQDDSVVACVTVQGGLESEIMTVSRYGYGKRTLI DRYRVQSRGGKGVINFKVTPKTGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRATQGVRLVWLDEGDHVVGFDR VSEQEQEQLDD
Sequences:
>Translated_811_residues MSNQVTIEDELKKSYLEYSLSVIIGRAIPDVRDGLKPVHRRIMFAQHELGNGYNRAPKKSARVVGDVIGKYHPHGDFAVY DALVRMAQDFSMRDPLVTGQGNFGSIDGDSAAAMRYTEVRMSRLASEFMADIDKETVEFRPNYDNTLQEPAVLPTKVPNL LLNGSSGIAVGMATNIPPHNLGELVDGLLLELDSPECTVADLAGLVKGPDFPTGGFCYAGRGLRDAYETGRGTVKIRGRV EVEERKKGFQSIVIREIPYALNKSSLVEKIAALANERRIEGITDLRDESDRRGIRVVIDLKRGTIPEIVINQLYKYTPLE TSFGINMLAVVGNRPQLLTLKKVFECFLQHRREVIIRRTHYDLRKAEARAHILEGLRIALDNIDEVVELIRASKTPPEAK ERLMQRFSLSEVQAQAILDMRLQRLTNLEHEKLIEEYRELLKKIEYFKSILENEEVLRGVIRDELKELKETYATPRRTEM LEDELEGIDIEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHTGDGDFVQDFLVTTNHQYLLLFTNKGRMF QLKVHQVPEGSRTAKGMHINNLLPMEENEWVNTALTIREFTEEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGD ELIMVREVDDNCEVVLTTEKGIAIRFGCGDVRPMGRSATGVKGIALSQDDSVVACVTVQGGLESEIMTVSRYGYGKRTLI DRYRVQSRGGKGVINFKVTPKTGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRATQGVRLVWLDEGDHVVGFDR VSEQEQEQLDD >Mature_810_residues SNQVTIEDELKKSYLEYSLSVIIGRAIPDVRDGLKPVHRRIMFAQHELGNGYNRAPKKSARVVGDVIGKYHPHGDFAVYD ALVRMAQDFSMRDPLVTGQGNFGSIDGDSAAAMRYTEVRMSRLASEFMADIDKETVEFRPNYDNTLQEPAVLPTKVPNLL LNGSSGIAVGMATNIPPHNLGELVDGLLLELDSPECTVADLAGLVKGPDFPTGGFCYAGRGLRDAYETGRGTVKIRGRVE VEERKKGFQSIVIREIPYALNKSSLVEKIAALANERRIEGITDLRDESDRRGIRVVIDLKRGTIPEIVINQLYKYTPLET SFGINMLAVVGNRPQLLTLKKVFECFLQHRREVIIRRTHYDLRKAEARAHILEGLRIALDNIDEVVELIRASKTPPEAKE RLMQRFSLSEVQAQAILDMRLQRLTNLEHEKLIEEYRELLKKIEYFKSILENEEVLRGVIRDELKELKETYATPRRTEML EDELEGIDIEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHTGDGDFVQDFLVTTNHQYLLLFTNKGRMFQ LKVHQVPEGSRTAKGMHINNLLPMEENEWVNTALTIREFTEEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGDE LIMVREVDDNCEVVLTTEKGIAIRFGCGDVRPMGRSATGVKGIALSQDDSVVACVTVQGGLESEIMTVSRYGYGKRTLID RYRVQSRGGKGVINFKVTPKTGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRATQGVRLVWLDEGDHVVGFDRV SEQEQEQLDD
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=363, Percent_Identity=25.068870523416, Blast_Score=74, Evalue=7e-13, Organism=Homo sapiens, GI19913408, Length=364, Percent_Identity=23.9010989010989, Blast_Score=73, Evalue=9e-13, Organism=Escherichia coli, GI1788562, Length=842, Percent_Identity=49.1686460807601, Blast_Score=805, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=682, Percent_Identity=35.4838709677419, Blast_Score=392, Evalue=1e-110, Organism=Caenorhabditis elegans, GI212645845, Length=396, Percent_Identity=23.989898989899, Blast_Score=75, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17535065, Length=365, Percent_Identity=23.8356164383562, Blast_Score=73, Evalue=5e-13, Organism=Caenorhabditis elegans, GI212645657, Length=384, Percent_Identity=23.1770833333333, Blast_Score=72, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=189, Percent_Identity=28.042328042328, Blast_Score=74, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 91226; Mature: 91095
Theoretical pI: Translated: 6.89; Mature: 6.89
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNQVTIEDELKKSYLEYSLSVIIGRAIPDVRDGLKPVHRRIMFAQHELGNGYNRAPKKS CCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH ARVVGDVIGKYHPHGDFAVYDALVRMAQDFSMRDPLVTGQGNFGSIDGDSAAAMRYTEVR HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH MSRLASEFMADIDKETVEFRPNYDNTLQEPAVLPTKVPNLLLNGSSGIAVGMATNIPPHN HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCC LGELVDGLLLELDSPECTVADLAGLVKGPDFPTGGFCYAGRGLRDAYETGRGTVKIRGRV HHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHCCCCEEEEEEEE EVEERKKGFQSIVIREIPYALNKSSLVEKIAALANERRIEGITDLRDESDRRGIRVVIDL EHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEE KRGTIPEIVINQLYKYTPLETSFGINMLAVVGNRPQLLTLKKVFECFLQHRREVIIRRTH CCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH YDLRKAEARAHILEGLRIALDNIDEVVELIRASKTPPEAKERLMQRFSLSEVQAQAILDM HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH RLQRLTNLEHEKLIEEYRELLKKIEYFKSILENEEVLRGVIRDELKELKETYATPRRTEM HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH LEDELEGIDIEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHTGDGDFVQD HHHHHCCCCHHHCCCCCCEEEEEECCCCEECCCCHHHHHHHCCCCCEEEEECCCCHHHHH FLVTTNHQYLLLFTNKGRMFQLKVHQVPEGSRTAKGMHINNLLPMEENEWVNTALTIREF HHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHEEEHHHH TEEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGDELIMVREVDDNCEVVLTTEK CCCCEEEEECCCCHHCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCCEEEEECC GIAIRFGCGDVRPMGRSATGVKGIALSQDDSVVACVTVQGGLESEIMTVSRYGYGKRTLI CEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHEEHHHCCCCCHHHH DRYRVQSRGGKGVINFKVTPKTGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRA HHHHHHCCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEECCCCEEEECHHHHHHHHHH TQGVRLVWLDEGDHVVGFDRVSEQEQEQLDD CCCEEEEEEECCCEEEEHHHHCHHHHHHCCC >Mature Secondary Structure SNQVTIEDELKKSYLEYSLSVIIGRAIPDVRDGLKPVHRRIMFAQHELGNGYNRAPKKS CCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH ARVVGDVIGKYHPHGDFAVYDALVRMAQDFSMRDPLVTGQGNFGSIDGDSAAAMRYTEVR HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH MSRLASEFMADIDKETVEFRPNYDNTLQEPAVLPTKVPNLLLNGSSGIAVGMATNIPPHN HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCC LGELVDGLLLELDSPECTVADLAGLVKGPDFPTGGFCYAGRGLRDAYETGRGTVKIRGRV HHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHCCCCEEEEEEEE EVEERKKGFQSIVIREIPYALNKSSLVEKIAALANERRIEGITDLRDESDRRGIRVVIDL EHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEE KRGTIPEIVINQLYKYTPLETSFGINMLAVVGNRPQLLTLKKVFECFLQHRREVIIRRTH CCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH YDLRKAEARAHILEGLRIALDNIDEVVELIRASKTPPEAKERLMQRFSLSEVQAQAILDM HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH RLQRLTNLEHEKLIEEYRELLKKIEYFKSILENEEVLRGVIRDELKELKETYATPRRTEM HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH LEDELEGIDIEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHTGDGDFVQD HHHHHCCCCHHHCCCCCCEEEEEECCCCEECCCCHHHHHHHCCCCCEEEEECCCCHHHHH FLVTTNHQYLLLFTNKGRMFQLKVHQVPEGSRTAKGMHINNLLPMEENEWVNTALTIREF HHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHEEEHHHH TEEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGDELIMVREVDDNCEVVLTTEK CCCCEEEEECCCCHHCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCCEEEEECC GIAIRFGCGDVRPMGRSATGVKGIALSQDDSVVACVTVQGGLESEIMTVSRYGYGKRTLI CEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCHHHEEHHHCCCCCHHHH DRYRVQSRGGKGVINFKVTPKTGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRA HHHHHHCCCCCEEEEEEECCCCCCHHEEEEEECCCCEEEEECCCCEEEECHHHHHHHHHH TQGVRLVWLDEGDHVVGFDRVSEQEQEQLDD CCCEEEEEEECCCEEEEHHHHCHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11466286 [H]