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The map label for this gene is dhaR [H]

Identifier: 78224653

GI number: 78224653

Start: 3881774

End: 3882376

Strand: Reverse

Name: dhaR [H]

Synonym: Gmet_3466

Alternate gene names: 78224653

Gene position: 3882376-3881774 (Counterclockwise)

Preceding gene: 78224658

Following gene: 78224652

Centisome position: 97.12

GC content: 55.06

Gene sequence:

>603_bases
ATGAAACCACGAAAAAAAGAGCCCACGGAAGTAAGGCGACAGCAGATTACCGAGGCGGCCCTCAGGATTATCGGAACGAA
AGGAATAAGCGGCGCAACAACAGCGGAGATCGCCTCTGCGAGCGGCATCTCCGAAGGGAACCTTTACCGGCACTTCAAGG
GGAAGGAAGAGATCCTCGGGTCGGTGATCGACAAGATCGGAAACGATCTCGCATCGATTCTCGATGCCGCTGCGGATATC
GCCGAACCACTGCGCAGACTTGAGGAAATCTTCAAGCGGCACCTCTCGTACATCGAAGAGCATGTGGGCATTCCCCGCAC
CATCTTCACCGAGGAGGTTCTGGTGCTGAACGAGACCCTCCGGGAAAAAGTCAGGGGAAATCTCATGCACTATTTCAGGG
GGATCAGCGCCGTTATCGAACAGGGACAGGAAGCGGGGGCATTGAACAGGGAAATGGACCCGAACGCTCTGGCCACCATG
TTCATCGGCACGGTCAATTTTACCGCCCTGCGGTGGGTAATGAACAAGTTTTCCTCGAAACTGAGCGATGAGGGGGAAAG
GCTCTGGGAAACCTTTGTGAAGTCGCTCGTCTGCAAGGTGTGA

Upstream 100 bases:

>100_bases
GCCAGAGAAATAGCCCTTTTTGACTTAGATCAAACTCAAACCGGGAGGGAGCCTGCAATACTGTCATGCAAGTAACCGCT
CACTTGCAAAGAGACCGACC

Downstream 100 bases:

>100_bases
GATTGCAGGCAAGATCTTTCAACTCGCTCACTAGTGAGAGGCGCTCATTCAGCACGGAAAAAAGACTGGCGCCATCGGGC
ATGTTGTTGATCCGGCGGCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKPRKKEPTEVRRQQITEAALRIIGTKGISGATTAEIASASGISEGNLYRHFKGKEEILGSVIDKIGNDLASILDAAADI
AEPLRRLEEIFKRHLSYIEEHVGIPRTIFTEEVLVLNETLREKVRGNLMHYFRGISAVIEQGQEAGALNREMDPNALATM
FIGTVNFTALRWVMNKFSSKLSDEGERLWETFVKSLVCKV

Sequences:

>Translated_200_residues
MKPRKKEPTEVRRQQITEAALRIIGTKGISGATTAEIASASGISEGNLYRHFKGKEEILGSVIDKIGNDLASILDAAADI
AEPLRRLEEIFKRHLSYIEEHVGIPRTIFTEEVLVLNETLREKVRGNLMHYFRGISAVIEQGQEAGALNREMDPNALATM
FIGTVNFTALRWVMNKFSSKLSDEGERLWETFVKSLVCKV
>Mature_200_residues
MKPRKKEPTEVRRQQITEAALRIIGTKGISGATTAEIASASGISEGNLYRHFKGKEEILGSVIDKIGNDLASILDAAADI
AEPLRRLEEIFKRHLSYIEEHVGIPRTIFTEEVLVLNETLREKVRGNLMHYFRGISAVIEQGQEAGALNREMDPNALATM
FIGTVNFTALRWVMNKFSSKLSDEGERLWETFVKSLVCKV

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22402; Mature: 22402

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRKKEPTEVRRQQITEAALRIIGTKGISGATTAEIASASGISEGNLYRHFKGKEEILG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH
SVIDKIGNDLASILDAAADIAEPLRRLEEIFKRHLSYIEEHVGIPRTIFTEEVLVLNETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
REKVRGNLMHYFRGISAVIEQGQEAGALNREMDPNALATMFIGTVNFTALRWVMNKFSSK
HHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSDEGERLWETFVKSLVCKV
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPRKKEPTEVRRQQITEAALRIIGTKGISGATTAEIASASGISEGNLYRHFKGKEEILG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH
SVIDKIGNDLASILDAAADIAEPLRRLEEIFKRHLSYIEEHVGIPRTIFTEEVLVLNETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
REKVRGNLMHYFRGISAVIEQGQEAGALNREMDPNALATMFIGTVNFTALRWVMNKFSSK
HHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSDEGERLWETFVKSLVCKV
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]