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The map label for this gene is metX

Identifier: 78223979

GI number: 78223979

Start: 3145778

End: 3146887

Strand: Direct

Name: metX

Synonym: Gmet_2783

Alternate gene names: 78223979

Gene position: 3145778-3146887 (Clockwise)

Preceding gene: 78223978

Following gene: 78223980

Centisome position: 78.7

GC content: 65.05

Gene sequence:

>1110_bases
ATGTCCGTCGGCATCGTACAGGAACAATCAGTAACCTTCGACACGGAACTCCGGCTGGAGAGCGGCCGCATTCTCGGCCC
CATCACCCTCGCCTACGAGACCTACGGCGAGCTGAACGCCGACCGCTCCAACGCGATCCTGGTGGCCCACGCCTGGACCG
GAAACGCCCATCTGGCGGGGAAAAACAGCGAGGAGGACACAAAGCCGGGATGGTGGGACGCCATCGTCGGCCCCGGCCGG
CTCCTGGACACCGACCGGTGCTTCGTCATCTGCTCCAACGTCATCGGCTCCTGCTACGGCTCCACCGGCCCCGCCTCCAT
CAACCCGAAAACCGGCAAGCGCTACAACCTCACCTTTCCCGTCATCACCGTCCGCGACATGGTCAGGGCCCAGGCCCTCC
TCCTCGACCACCTGGGAATCGACCGGCTCCTCACCGTCCTCGGCGGGAGCATGGGGGGGATGCAGGCCCTGGAGTGGGCC
ACCCAGTTCCCGGACCGGATCCGCTCCGCCATCGCCCTGGCCACCACGAGCCGCCCGTCGCCCCAGGCCATTTCCCTCAA
CGCCGTTGCCCGCTGGGCCATCTTCAACGACCCCACGTGGAAGAAGGGGGAATACCGCAAGAACCCCAAGGACGGCCTGG
CCCTGGCCCGGGGGATCGGCCACATCACCTTTCTCTCCGACGAGTCCATGTGGCAGAAGTTCGGCCGCCGCTTCAACGCC
CGGGACGGCCTCTTCGACTTCTTCGGCCAGTTCGAGGTGGAGCGCTACCTCTCCTACAACGGCTACAACTTCGTGGACCG
CTTCGACACCAACTCCTTCCTCTACCTGGCCAAGGCCCTGGACCTCTACGACACGGCCTGGGGGTACGAATCCCTGGAGG
AGGCGTTTTCCCGGGTAAAGGCGCCGATCCAGTTCTTCGCCTTCACCTCCGACTGGCTCTACCCCCCCTACCAGACCGAG
GAGATGGCGACCATCCTCCGCTCCCTCGGCAAGCCGGTCGAATACCACCTGATCGAATCGGCCTACGGCCACGACGCCTT
CCTCCTGGAACACGAGACCTTCGCGCCGATGGTGCGGGAATTCCTCGACAAGGTGGAACGTTCGGAGTAG

Upstream 100 bases:

>100_bases
GAGAACGGCGCTTGACGATAGCCACAACTGTCAACAAAGCCCCTTCTCGCCACCGCGGGAAGGGGCTTTTGTTTCCGAAC
CATTTATTCAGGATTGACGC

Downstream 100 bases:

>100_bases
CCTCGGGTGAACATTGCGTTGCAGTGATGCACTGCCGGGAGGTGAACGATGGCGAGGAAGATCTTCATAGCGGCCACGGG
ACAGAACTGCGGCAAGACCA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAGKNSEEDTKPGWWDAIVGPGR
LLDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFPVITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWA
TQFPDRIRSAIALATTSRPSPQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNA
RDGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVKAPIQFFAFTSDWLYPPYQTE
EMATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVREFLDKVERSE

Sequences:

>Translated_369_residues
MSVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAGKNSEEDTKPGWWDAIVGPGR
LLDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFPVITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWA
TQFPDRIRSAIALATTSRPSPQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNA
RDGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVKAPIQFFAFTSDWLYPPYQTE
EMATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVREFLDKVERSE
>Mature_368_residues
SVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAGKNSEEDTKPGWWDAIVGPGRL
LDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFPVITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWAT
QFPDRIRSAIALATTSRPSPQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNAR
DGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVKAPIQFFAFTSDWLYPPYQTEE
MATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVREFLDKVERSE

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=236, Percent_Identity=39.4067796610169, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_GEOMG (Q39RX3)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385726.1
- STRING:   Q39RX3
- GeneID:   3739286
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2783
- NMPDR:   fig|269799.3.peg.2761
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q39RX3
- ProtClustDB:   CLSK828845
- BioCyc:   GMET269799:GMET_2783-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41582; Mature: 41451

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: ACT_SITE 150-150 ACT_SITE 344-344

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAG
CCCCCEECCCCEEEEEEEECCCCEEEEEEEEEEHHCCCCCCCCCEEEEEEEECCCEEECC
KNSEEDTKPGWWDAIVGPGRLLDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFP
CCCCCCCCCCCCHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWATQFPDRIRSAIALATTSRPS
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
PQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNA
CCEEEHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHCCCC
RDGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVK
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
APIQFFAFTSDWLYPPYQTEEMATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVRE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCEEEEECHHHHHHHHH
FLDKVERSE
HHHHHHCCC
>Mature Secondary Structure 
SVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAG
CCCCEECCCCEEEEEEEECCCCEEEEEEEEEEHHCCCCCCCCCEEEEEEEECCCEEECC
KNSEEDTKPGWWDAIVGPGRLLDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFP
CCCCCCCCCCCCHHCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWATQFPDRIRSAIALATTSRPS
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
PQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNA
CCEEEHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHCCCC
RDGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVK
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
APIQFFAFTSDWLYPPYQTEEMATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVRE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCEEEEECHHHHHHHHH
FLDKVERSE
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA