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The map label for this gene is aphA [H]

Identifier: 78223958

GI number: 78223958

Start: 3119614

End: 3121290

Strand: Reverse

Name: aphA [H]

Synonym: Gmet_2762

Alternate gene names: 78223958

Gene position: 3121290-3119614 (Counterclockwise)

Preceding gene: 78223959

Following gene: 78223957

Centisome position: 78.08

GC content: 64.16

Gene sequence:

>1677_bases
GTGAGTCTGAACAGAGCGACCCTATGGGCACTGCTGGTATTTTCGCTTTTCATGGGGATGGGCGCGGTACTTGCCGGCGA
GCTGGCGCGCGAGCGGAAGCAGGAGTACCGCCAAACCGTGTCCCAGATTGCCGCCAACGCGGCCCATTCCCTTGATCATC
AGCTTTTTCGCTCCCTGTCGGCCACCAACGCCCTGGCCGCCATCCTCCGACAACAGGGCAGAATTGAGAATTTCGCCTCC
CTGGCGGCGGAGATGATCAAGGTCTACGGCGGCATCGACACTCTCCAGCTGGTGCCCGAGGGGGTCATAACCGAGGTCTA
CCCCCTTGCCGGCAACGAAAAGGCCGTCGGGTTCGACATCCTCCGGGACCCTGTTCGCAGCTTCGAAGCGCTGCGGGCCA
TCGAGTCCCGCCGGCTTTCCCTCGATGGTCCCTTCGAGCTCAAACAGGGGGGGAAGGCGGTTGTGGGGCGGCAGGCGGTG
TTCCTTTCCGACGGCCGGGGAGGCGAGCGGTTCTGGGGGTTTACGGCGGCCATCATCCGGCTGCGGACCCTTATGGACGC
CAGCAACCTGAACCTTCTCGCAAAAAACGGCTATGCGTATCGGGTATCCCGCCTCCATCCCGGCAGCGGTGAAAAAATTG
TAGTTGCCCAAGGGGGGGGGACTCTCCTGGCAGATCCGGTGGAGTTTGCCTTCGACGTGCCCAACGGGAAATGGGTACTC
TCGGTGTCGCCGTCGGGGGGATGGCTCACGCGCTCGGGAATAGTGTGGTACGGCGCCACGGTTATCCTGGTCAGCCTGGC
GATGGGGAGTCTTGCCTACCTGTTCCAGCGGCAGCCGGCGCTGTTGCGGATCGAAGTGGCAAAACGGACGGCCGAGCTCC
AGACGGCCAGGGGGCGTCTCGAAGAGGAAGCACGGGAGCGGGCGCGGGTCGAGGAGGAGGTTCGGCGTCTCAATGCCGAT
CTGGAGCAGCGGGTTGCCGAGAGGACTTCCCAGTTGGCGGCCGTCAACCAGGAGCTGGAATTGTTCACCTATTCGGTTTC
CCACGACCTTCGGGCGCCTCTGAACACCATTGAAGGCTTTACCCGGACCCTCAGGGAAGAGCACGCCGGCTCCCTGGACG
AAAACGGCATGCAGATCCTGATGCGGATATGCAAGGCCGGTGACCGGATGAAGGAGCTCATCGGCCATCTCCACGAGTTG
TCCCGGGTGAGCGCCGGCGAACTGGTTCGCCAGAGCGTCGATCTTGGCGCCATGGCCCGGGAAATCGCCGCGGATCTCCA
GGGGGGCGATCCTGGCCGCTCCGTGACCTTCCGTATTGCCGACGGGGTTATGGCGCCGGGCGATGCGGGGCTTCTGCGGG
TTGCCCTGGAAAACCTTCTGGGCAATGCCTGGAAATATACCGGGGGAAAAGAGGGGGCGCTGATCGAATTCGGGGTGGAG
GCCGAGGAGGGGGAGCGGTTTTTTTTCGTCCGGGACAACGGCGCCGGCTTCGACATGAAATACGCCGACAGGCTCTTCGG
CGTGTTCCAGCGGCTGCACGGCGCCGCGGAGTTCGAGGGGACCGGCGTCGGCCTGGCCACGGTGCGGCGGATAATCCTCC
GTCACGGGGGGCGGATTTGGGCGGAGGGGGCGGTCGGCCGTGGAGCCACCTTCTTCTTTACCCTGGGCGAGGAGTAG

Upstream 100 bases:

>100_bases
GGCAGGAGCTTCTGGCCGGGGGGACCCTGAACTTTGTGAAAAAAGGCGGTACGGAGGGGTGAGGGCATAAGGGAATGGAT
GGGCCGTGGAGCACAAGCCG

Downstream 100 bases:

>100_bases
TGGCATGGGGAGGATTCGGCCATGAAGCATGGCGGTCCGATACGGGGGGCGATCCTGCTCTTCGCTTTGTTTCTGGGAGC
CGGGTCGGTCTTCGTGCGCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSLNRATLWALLVFSLFMGMGAVLAGELARERKQEYRQTVSQIAANAAHSLDHQLFRSLSATNALAAILRQQGRIENFAS
LAAEMIKVYGGIDTLQLVPEGVITEVYPLAGNEKAVGFDILRDPVRSFEALRAIESRRLSLDGPFELKQGGKAVVGRQAV
FLSDGRGGERFWGFTAAIIRLRTLMDASNLNLLAKNGYAYRVSRLHPGSGEKIVVAQGGGTLLADPVEFAFDVPNGKWVL
SVSPSGGWLTRSGIVWYGATVILVSLAMGSLAYLFQRQPALLRIEVAKRTAELQTARGRLEEEARERARVEEEVRRLNAD
LEQRVAERTSQLAAVNQELELFTYSVSHDLRAPLNTIEGFTRTLREEHAGSLDENGMQILMRICKAGDRMKELIGHLHEL
SRVSAGELVRQSVDLGAMAREIAADLQGGDPGRSVTFRIADGVMAPGDAGLLRVALENLLGNAWKYTGGKEGALIEFGVE
AEEGERFFFVRDNGAGFDMKYADRLFGVFQRLHGAAEFEGTGVGLATVRRIILRHGGRIWAEGAVGRGATFFFTLGEE

Sequences:

>Translated_558_residues
MSLNRATLWALLVFSLFMGMGAVLAGELARERKQEYRQTVSQIAANAAHSLDHQLFRSLSATNALAAILRQQGRIENFAS
LAAEMIKVYGGIDTLQLVPEGVITEVYPLAGNEKAVGFDILRDPVRSFEALRAIESRRLSLDGPFELKQGGKAVVGRQAV
FLSDGRGGERFWGFTAAIIRLRTLMDASNLNLLAKNGYAYRVSRLHPGSGEKIVVAQGGGTLLADPVEFAFDVPNGKWVL
SVSPSGGWLTRSGIVWYGATVILVSLAMGSLAYLFQRQPALLRIEVAKRTAELQTARGRLEEEARERARVEEEVRRLNAD
LEQRVAERTSQLAAVNQELELFTYSVSHDLRAPLNTIEGFTRTLREEHAGSLDENGMQILMRICKAGDRMKELIGHLHEL
SRVSAGELVRQSVDLGAMAREIAADLQGGDPGRSVTFRIADGVMAPGDAGLLRVALENLLGNAWKYTGGKEGALIEFGVE
AEEGERFFFVRDNGAGFDMKYADRLFGVFQRLHGAAEFEGTGVGLATVRRIILRHGGRIWAEGAVGRGATFFFTLGEE
>Mature_557_residues
SLNRATLWALLVFSLFMGMGAVLAGELARERKQEYRQTVSQIAANAAHSLDHQLFRSLSATNALAAILRQQGRIENFASL
AAEMIKVYGGIDTLQLVPEGVITEVYPLAGNEKAVGFDILRDPVRSFEALRAIESRRLSLDGPFELKQGGKAVVGRQAVF
LSDGRGGERFWGFTAAIIRLRTLMDASNLNLLAKNGYAYRVSRLHPGSGEKIVVAQGGGTLLADPVEFAFDVPNGKWVLS
VSPSGGWLTRSGIVWYGATVILVSLAMGSLAYLFQRQPALLRIEVAKRTAELQTARGRLEEEARERARVEEEVRRLNADL
EQRVAERTSQLAAVNQELELFTYSVSHDLRAPLNTIEGFTRTLREEHAGSLDENGMQILMRICKAGDRMKELIGHLHELS
RVSAGELVRQSVDLGAMAREIAADLQGGDPGRSVTFRIADGVMAPGDAGLLRVALENLLGNAWKYTGGKEGALIEFGVEA
EEGERFFFVRDNGAGFDMKYADRLFGVFQRLHGAAEFEGTGVGLATVRRIILRHGGRIWAEGAVGRGATFFFTLGEE

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=29.2887029288703, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=28.6259541984733, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788549, Length=213, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=206, Percent_Identity=29.126213592233, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61050; Mature: 60918

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50839 CHASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNRATLWALLVFSLFMGMGAVLAGELARERKQEYRQTVSQIAANAAHSLDHQLFRSLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATNALAAILRQQGRIENFASLAAEMIKVYGGIDTLQLVPEGVITEVYPLAGNEKAVGFDI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHEEECCCCCCCCHHHH
LRDPVRSFEALRAIESRRLSLDGPFELKQGGKAVVGRQAVFLSDGRGGERFWGFTAAIIR
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCEEEEEECCCCCCHHHHHHHHHHH
LRTLMDASNLNLLAKNGYAYRVSRLHPGSGEKIVVAQGGGTLLADPVEFAFDVPNGKWVL
HHHHHCCCCCEEEEECCCEEEEEEECCCCCCEEEEECCCCEEEECCHHHEEECCCCCEEE
SVSPSGGWLTRSGIVWYGATVILVSLAMGSLAYLFQRQPALLRIEVAKRTAELQTARGRL
EECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
EEEARERARVEEEVRRLNADLEQRVAERTSQLAAVNQELELFTYSVSHDLRAPLNTIEGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHCHHHHHHHH
TRTLREEHAGSLDENGMQILMRICKAGDRMKELIGHLHELSRVSAGELVRQSVDLGAMAR
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIAADLQGGDPGRSVTFRIADGVMAPGDAGLLRVALENLLGNAWKYTGGKEGALIEFGVE
HHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEECCC
AEEGERFFFVRDNGAGFDMKYADRLFGVFQRLHGAAEFEGTGVGLATVRRIILRHGGRIW
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEE
AEGAVGRGATFFFTLGEE
ECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SLNRATLWALLVFSLFMGMGAVLAGELARERKQEYRQTVSQIAANAAHSLDHQLFRSLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATNALAAILRQQGRIENFASLAAEMIKVYGGIDTLQLVPEGVITEVYPLAGNEKAVGFDI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHEEECCCCCCCCHHHH
LRDPVRSFEALRAIESRRLSLDGPFELKQGGKAVVGRQAVFLSDGRGGERFWGFTAAIIR
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCEEEEEECCCCCCHHHHHHHHHHH
LRTLMDASNLNLLAKNGYAYRVSRLHPGSGEKIVVAQGGGTLLADPVEFAFDVPNGKWVL
HHHHHCCCCCEEEEECCCEEEEEEECCCCCCEEEEECCCCEEEECCHHHEEECCCCCEEE
SVSPSGGWLTRSGIVWYGATVILVSLAMGSLAYLFQRQPALLRIEVAKRTAELQTARGRL
EECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
EEEARERARVEEEVRRLNADLEQRVAERTSQLAAVNQELELFTYSVSHDLRAPLNTIEGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHCHHHHHHHH
TRTLREEHAGSLDENGMQILMRICKAGDRMKELIGHLHELSRVSAGELVRQSVDLGAMAR
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIAADLQGGDPGRSVTFRIADGVMAPGDAGLLRVALENLLGNAWKYTGGKEGALIEFGVE
HHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEECCC
AEEGERFFFVRDNGAGFDMKYADRLFGVFQRLHGAAEFEGTGVGLATVRRIILRHGGRIW
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEE
AEGAVGRGATFFFTLGEE
ECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]