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The map label for this gene is recQ [H]

Identifier: 78223913

GI number: 78223913

Start: 3068824

End: 3070629

Strand: Reverse

Name: recQ [H]

Synonym: Gmet_2717

Alternate gene names: 78223913

Gene position: 3070629-3068824 (Counterclockwise)

Preceding gene: 78223914

Following gene: 78223912

Centisome position: 76.82

GC content: 67.61

Gene sequence:

>1806_bases
GTGATCGCCAACAATCCCCTCGACACCCTCCGGACGGTCTTCGGCTACCGCACCTTCCGCCCCTTCCAGGAGGAGATCGT
CACCCGTCTCATCGGCGGCGGCGATGCCTTTGTCCTCATGCCGACGGGGGGCGGAAAGTCCCTCTGCTACCAGATTCCGG
CCATCCACCGTCCCGGCGTCGGCATCGTGGTCTCTCCCCTCATCTCCCTCATGAAGGACCAGGTGGATACGCTGCGGGAG
AACGGCGTGGCGGCCGCGGCCTACAATTCCGCCATGGGCGAGCGGGAGGCCCGGCAGGTCCTGGCCCGGCTCCACGCGGG
CGAGCTGGATCTCCTCTACGTGGCGCCGGAGCGGCTCATGACCGACGCCTTTCTGGAGCGGCTCCGGGAGATCCCCGTGG
CCCTTTTCGCCATCGACGAGGCCCACTGCGTTTCCCAGTGGGGGCACGACTTCCGCCCCGAGTACGTGGGGCTGGGGCGG
CTGCGGGGGCTCTTCCCCGGCGTGCCGGTCATCGCCCTCACCGCCACCGCCGACGTCCAGACCCGCAGCGACATCATCGA
CCGGCTGGGGCTTCGGGACGCCCAGGTCTACGTCACCGGCTTCGACCGGCCGAACATCCGGTACACCGTGGTCGATAAGC
AGAAGCCCTTTCACCAGCTCCTGGCGTTTCTGGGGAACCGCCCTCAGGATGCCGGCATCGTCTACGCCCTCTCCAGAAAG
CGGGTGGAGGAGGTGGCCGGCAAGCTGCGGGATGCCGGCATCGAGGCGGCCGCCTACCATGCGGGGCTGGCCGACGGCGA
GCGGGGCCGGGTCCAGGAGGCGTTCCTGCGGGATGATGTCCGCGTTGTGGTGGCCACCGTCGCCTTCGGCATGGGGATCG
ACAAGCCCAACGTCCGGTTCGTGGTCCACTACGACCTTCCCAAGAACATCGAGAGCTACTACCAGGAGACGGGCCGGGCC
GGGCGCGACGGGCTGCCGGCCGAGGCGCTCCTTCTCTTCGGCTATGGAGATATTGCCGTCTCCCGCTCCCTCATCGAGTC
CGGCAACAATCCGGAACAGGTGCGGATCGAGCTCCACAAGCTGAACGCCATGGTGGGGTTCGCCGAGGCCGGCACCTGCC
GCCGGGAGGCGCTCCTGGGCTATTTCGGCGAGCGGCTTGCCGAGCCGTGCGGCAACTGCGATCTCTGTCTCGATCCCCCC
GAGAGCTTCGACGCCACCGAGGATGCCCGCAAGGCCCTCTCCTGCGTCTACCGGGTGGGGCAGCGCTTCGGCATGGGGCA
TGTGATCGACGTGCTGCGGGGCTCGAAAAACGAGCGGATCCAGCAGCTGGGCCACGATCGCCTCTCCACCTACGGCATCG
GCGCGGACCGCTCCGCCGAGGCGTGGGGAAGCATCATCCGCCAGCTTATTCATCGCGGGTACCTGGAGCAGGACCTGGCC
AACTATTCGGTGCTGAAGCTGACCCCGGCGGCCCGTCCCCTGTTGCGGGGGGAGGTGAGCCTGACCCTTGCGAAGCCCCG
GGTGAAGGTTGCCCCGGTCAAAAAGGAGCCGAAGCGTAAGGGGGTAGTGGCATCGCTGGCCGAGAGGGACGAGGATCTCT
TCCAGGCGCTGAGGGCTCTCCGCAAGCGACTGGCCGACGAGCAGCAGGTCCCCCCCTATGTCATCTTCAGCGACGCCACG
CTGGTCGAGATGGCGACCCTGCGTCCCGCAACCATGGACGACCTCCTGCGGGTGAACGGGGTAGGGGAGCAGAAGCTCGG
GCGCTACGGCGCGGCGTTTCTTGAGGCGATTCGGAACAATTCGTGA

Upstream 100 bases:

>100_bases
CCTTCGGGAGCAAGGTCCGTTACATCCGCTCCTCAGCCCGGGGACGCGGCGCCCCCGATGGGCAGTATGTCTATCTCGGC
TTTCGGGTGCTGAGGGAACT

Downstream 100 bases:

>100_bases
GTATTTGTTTCTGAGCGAAATTTTCATTTCCACTATTTTCAACGCCCGGAGGTTCCCATGTCCGTCACCCTCGACGAGGT
AAAACAAGTCTACGCGGAGG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MIANNPLDTLRTVFGYRTFRPFQEEIVTRLIGGGDAFVLMPTGGGKSLCYQIPAIHRPGVGIVVSPLISLMKDQVDTLRE
NGVAAAAYNSAMGEREARQVLARLHAGELDLLYVAPERLMTDAFLERLREIPVALFAIDEAHCVSQWGHDFRPEYVGLGR
LRGLFPGVPVIALTATADVQTRSDIIDRLGLRDAQVYVTGFDRPNIRYTVVDKQKPFHQLLAFLGNRPQDAGIVYALSRK
RVEEVAGKLRDAGIEAAAYHAGLADGERGRVQEAFLRDDVRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRA
GRDGLPAEALLLFGYGDIAVSRSLIESGNNPEQVRIELHKLNAMVGFAEAGTCRREALLGYFGERLAEPCGNCDLCLDPP
ESFDATEDARKALSCVYRVGQRFGMGHVIDVLRGSKNERIQQLGHDRLSTYGIGADRSAEAWGSIIRQLIHRGYLEQDLA
NYSVLKLTPAARPLLRGEVSLTLAKPRVKVAPVKKEPKRKGVVASLAERDEDLFQALRALRKRLADEQQVPPYVIFSDAT
LVEMATLRPATMDDLLRVNGVGEQKLGRYGAAFLEAIRNNS

Sequences:

>Translated_601_residues
MIANNPLDTLRTVFGYRTFRPFQEEIVTRLIGGGDAFVLMPTGGGKSLCYQIPAIHRPGVGIVVSPLISLMKDQVDTLRE
NGVAAAAYNSAMGEREARQVLARLHAGELDLLYVAPERLMTDAFLERLREIPVALFAIDEAHCVSQWGHDFRPEYVGLGR
LRGLFPGVPVIALTATADVQTRSDIIDRLGLRDAQVYVTGFDRPNIRYTVVDKQKPFHQLLAFLGNRPQDAGIVYALSRK
RVEEVAGKLRDAGIEAAAYHAGLADGERGRVQEAFLRDDVRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRA
GRDGLPAEALLLFGYGDIAVSRSLIESGNNPEQVRIELHKLNAMVGFAEAGTCRREALLGYFGERLAEPCGNCDLCLDPP
ESFDATEDARKALSCVYRVGQRFGMGHVIDVLRGSKNERIQQLGHDRLSTYGIGADRSAEAWGSIIRQLIHRGYLEQDLA
NYSVLKLTPAARPLLRGEVSLTLAKPRVKVAPVKKEPKRKGVVASLAERDEDLFQALRALRKRLADEQQVPPYVIFSDAT
LVEMATLRPATMDDLLRVNGVGEQKLGRYGAAFLEAIRNNS
>Mature_601_residues
MIANNPLDTLRTVFGYRTFRPFQEEIVTRLIGGGDAFVLMPTGGGKSLCYQIPAIHRPGVGIVVSPLISLMKDQVDTLRE
NGVAAAAYNSAMGEREARQVLARLHAGELDLLYVAPERLMTDAFLERLREIPVALFAIDEAHCVSQWGHDFRPEYVGLGR
LRGLFPGVPVIALTATADVQTRSDIIDRLGLRDAQVYVTGFDRPNIRYTVVDKQKPFHQLLAFLGNRPQDAGIVYALSRK
RVEEVAGKLRDAGIEAAAYHAGLADGERGRVQEAFLRDDVRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRA
GRDGLPAEALLLFGYGDIAVSRSLIESGNNPEQVRIELHKLNAMVGFAEAGTCRREALLGYFGERLAEPCGNCDLCLDPP
ESFDATEDARKALSCVYRVGQRFGMGHVIDVLRGSKNERIQQLGHDRLSTYGIGADRSAEAWGSIIRQLIHRGYLEQDLA
NYSVLKLTPAARPLLRGEVSLTLAKPRVKVAPVKKEPKRKGVVASLAERDEDLFQALRALRKRLADEQQVPPYVIFSDAT
LVEMATLRPATMDDLLRVNGVGEQKLGRYGAAFLEAIRNNS

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=635, Percent_Identity=37.1653543307087, Blast_Score=361, Evalue=1e-100,
Organism=Homo sapiens, GI110735439, Length=494, Percent_Identity=37.6518218623482, Blast_Score=332, Evalue=9e-91,
Organism=Homo sapiens, GI169218196, Length=494, Percent_Identity=37.6518218623482, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI14591902, Length=524, Percent_Identity=36.0687022900763, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI14591904, Length=524, Percent_Identity=36.0687022900763, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI148612816, Length=420, Percent_Identity=39.5238095238095, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI51242947, Length=390, Percent_Identity=39.7435897435897, Blast_Score=267, Evalue=3e-71,
Organism=Homo sapiens, GI51242943, Length=390, Percent_Identity=39.7435897435897, Blast_Score=267, Evalue=3e-71,
Organism=Homo sapiens, GI284005309, Length=359, Percent_Identity=38.7186629526462, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI7661920, Length=353, Percent_Identity=20.9631728045326, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI222352149, Length=359, Percent_Identity=23.6768802228412, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI48994977, Length=590, Percent_Identity=56.4406779661017, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI1787016, Length=344, Percent_Identity=25, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788930, Length=323, Percent_Identity=24.4582043343653, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=655, Percent_Identity=36.9465648854962, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32564293, Length=669, Percent_Identity=33.4828101644245, Blast_Score=322, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI71987997, Length=546, Percent_Identity=35.7142857142857, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI71987993, Length=546, Percent_Identity=35.7142857142857, Blast_Score=308, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI17552866, Length=415, Percent_Identity=37.5903614457831, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17507121, Length=354, Percent_Identity=22.5988700564972, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995724, Length=354, Percent_Identity=22.316384180791, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508543, Length=137, Percent_Identity=29.1970802919708, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=521, Percent_Identity=38.7715930902111, Blast_Score=347, Evalue=3e-96,
Organism=Saccharomyces cerevisiae, GI6320041, Length=345, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320224, Length=365, Percent_Identity=22.1917808219178, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322912, Length=333, Percent_Identity=22.5225225225225, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322323, Length=333, Percent_Identity=22.5225225225225, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325138, Length=147, Percent_Identity=27.891156462585, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=37.5987361769352, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24664226, Length=447, Percent_Identity=39.1498881431767, Blast_Score=296, Evalue=4e-80,
Organism=Drosophila melanogaster, GI62472181, Length=447, Percent_Identity=39.1498881431767, Blast_Score=291, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24664230, Length=447, Percent_Identity=39.1498881431767, Blast_Score=291, Evalue=9e-79,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=38.0281690140845, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28574962, Length=339, Percent_Identity=24.188790560472, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24645031, Length=352, Percent_Identity=21.875, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66346; Mature: 66346

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANNPLDTLRTVFGYRTFRPFQEEIVTRLIGGGDAFVLMPTGGGKSLCYQIPAIHRPGV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCC
GIVVSPLISLMKDQVDTLRENGVAAAAYNSAMGEREARQVLARLHAGELDLLYVAPERLM
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHCCCCEEEEEECHHHHH
TDAFLERLREIPVALFAIDEAHCVSQWGHDFRPEYVGLGRLRGLFPGVPVIALTATADVQ
HHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCHHCHHHHHHHCCCCCEEEEEECCCCH
TRSDIIDRLGLRDAQVYVTGFDRPNIRYTVVDKQKPFHQLLAFLGNRPQDAGIVYALSRK
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEHHHHH
RVEEVAGKLRDAGIEAAAYHAGLADGERGRVQEAFLRDDVRVVVATVAFGMGIDKPNVRF
HHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VVHYDLPKNIESYYQETGRAGRDGLPAEALLLFGYGDIAVSRSLIESGNNPEQVRIELHK
EEEECCCHHHHHHHHHHCCCCCCCCCHHEEEEEECCHHHHHHHHHHCCCCCHHEEEEHHH
LNAMVGFAEAGTCRREALLGYFGERLAEPCGNCDLCLDPPESFDATEDARKALSCVYRVG
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
QRFGMGHVIDVLRGSKNERIQQLGHDRLSTYGIGADRSAEAWGSIIRQLIHRGYLEQDLA
HHCCCHHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHC
NYSVLKLTPAARPLLRGEVSLTLAKPRVKVAPVKKEPKRKGVVASLAERDEDLFQALRAL
CCEEEEECCCCCHHHCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
RKRLADEQQVPPYVIFSDATLVEMATLRPATMDDLLRVNGVGEQKLGRYGAAFLEAIRNN
HHHCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MIANNPLDTLRTVFGYRTFRPFQEEIVTRLIGGGDAFVLMPTGGGKSLCYQIPAIHRPGV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCC
GIVVSPLISLMKDQVDTLRENGVAAAAYNSAMGEREARQVLARLHAGELDLLYVAPERLM
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCHHHHHHHHHHHCCCCEEEEEECHHHHH
TDAFLERLREIPVALFAIDEAHCVSQWGHDFRPEYVGLGRLRGLFPGVPVIALTATADVQ
HHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCHHCHHHHHHHCCCCCEEEEEECCCCH
TRSDIIDRLGLRDAQVYVTGFDRPNIRYTVVDKQKPFHQLLAFLGNRPQDAGIVYALSRK
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEHHHHH
RVEEVAGKLRDAGIEAAAYHAGLADGERGRVQEAFLRDDVRVVVATVAFGMGIDKPNVRF
HHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VVHYDLPKNIESYYQETGRAGRDGLPAEALLLFGYGDIAVSRSLIESGNNPEQVRIELHK
EEEECCCHHHHHHHHHHCCCCCCCCCHHEEEEEECCHHHHHHHHHHCCCCCHHEEEEHHH
LNAMVGFAEAGTCRREALLGYFGERLAEPCGNCDLCLDPPESFDATEDARKALSCVYRVG
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHH
QRFGMGHVIDVLRGSKNERIQQLGHDRLSTYGIGADRSAEAWGSIIRQLIHRGYLEQDLA
HHCCCHHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHC
NYSVLKLTPAARPLLRGEVSLTLAKPRVKVAPVKKEPKRKGVVASLAERDEDLFQALRAL
CCEEEEECCCCCHHHCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHH
RKRLADEQQVPPYVIFSDATLVEMATLRPATMDDLLRVNGVGEQKLGRYGAAFLEAIRNN
HHHCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]