Click here to switch to the map view.

The map label for this gene is pkn1 [H]

Identifier: 78223914

GI number: 78223914

Start: 3070626

End: 3071504

Strand: Reverse

Name: pkn1 [H]

Synonym: Gmet_2718

Alternate gene names: 78223914

Gene position: 3071504-3070626 (Counterclockwise)

Preceding gene: 78223918

Following gene: 78223913

Centisome position: 76.84

GC content: 66.1

Gene sequence:

>879_bases
ATGATGAATACCCACCGTCTGGCCACGGGAGCGGCGCTCCTGGCATTTCTCGTTATTGTATCGCCATTGGCTGCCGAAGT
GAAACCCGCGGCAAAAGTTTCTTCGCCTCCCCCCGCGGCCGGCTCGGTTTTCCGCGATCGCCTGAAGAATGGCTCCTCCG
GTCCCGAGATGGTGGTCATCCCCGCCGGCAAGTTCCGGATGGGGGCCATCTTCGGCGGCGGCGACCCCGACGAGAAGCCG
GTCCACTGGGTATCAATCGCCCGCCCCTTCGCCATGGGGAAGTATGAGGTGACCTTCGGGGAGTACGACCGGTTTTGCGA
TGCCACCGGCCGGGAGAAGCCCAAGGACGGCCGTCGCTGGTTCGGTCCTCTCTCCCGGGACTGGGGCCGGGGACGGATGC
CGGCCATGAACGTCAGCTGGGAGGATGCCGTAGCCTATGCCAAGTGGCTGTCGGAGCAGACGGGGCAGAAGTACCGGCTC
CCCAGCGAGGCCGAGTGGGAGTTCGCGGCCCGTGGCGGCAAGGATACCCCCTTCTGGTGGGGGGGAACCGCCGGCGAAAA
AAGGGCCAACTGCAAGGGGTGCGGCAGCAAGTGGGACAACAAGAAGGGTGCGCCGGCGGGCTCCTTCGCCGCGAATCCCT
ATGGCCTCTTCGATACGGCAGGCAACGTCTGGGAATGGTGCCTCGACACCTGGCACGACAGCTATACCGGAGCTCCCACT
GACGGCTCCCCCTGGCTCGGCGGCGACGACACCCGCCGCGTCCAGCGGGGTGGCTCCTTCGGGAGCAAGGTCCGTTACAT
CCGCTCCTCAGCCCGGGGACGCGGCGCCCCCGATGGGCAGTATGTCTATCTCGGCTTTCGGGTGCTGAGGGAACTGTGA

Upstream 100 bases:

>100_bases
GGTGGTTTTTTGCGGGGATCGCTTCTCCGCGAGAGCTCCACCCCTTCCGGGGACTAGCGGTGGAAAATGTGACATAAGTA
GAACTAAAGGAGTATCGGAT

Downstream 100 bases:

>100_bases
TCGCCAACAATCCCCTCGACACCCTCCGGACGGTCTTCGGCTACCGCACCTTCCGCCCCTTCCAGGAGGAGATCGTCACC
CGTCTCATCGGCGGCGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MMNTHRLATGAALLAFLVIVSPLAAEVKPAAKVSSPPPAAGSVFRDRLKNGSSGPEMVVIPAGKFRMGAIFGGGDPDEKP
VHWVSIARPFAMGKYEVTFGEYDRFCDATGREKPKDGRRWFGPLSRDWGRGRMPAMNVSWEDAVAYAKWLSEQTGQKYRL
PSEAEWEFAARGGKDTPFWWGGTAGEKRANCKGCGSKWDNKKGAPAGSFAANPYGLFDTAGNVWEWCLDTWHDSYTGAPT
DGSPWLGGDDTRRVQRGGSFGSKVRYIRSSARGRGAPDGQYVYLGFRVLREL

Sequences:

>Translated_292_residues
MMNTHRLATGAALLAFLVIVSPLAAEVKPAAKVSSPPPAAGSVFRDRLKNGSSGPEMVVIPAGKFRMGAIFGGGDPDEKP
VHWVSIARPFAMGKYEVTFGEYDRFCDATGREKPKDGRRWFGPLSRDWGRGRMPAMNVSWEDAVAYAKWLSEQTGQKYRL
PSEAEWEFAARGGKDTPFWWGGTAGEKRANCKGCGSKWDNKKGAPAGSFAANPYGLFDTAGNVWEWCLDTWHDSYTGAPT
DGSPWLGGDDTRRVQRGGSFGSKVRYIRSSARGRGAPDGQYVYLGFRVLREL
>Mature_292_residues
MMNTHRLATGAALLAFLVIVSPLAAEVKPAAKVSSPPPAAGSVFRDRLKNGSSGPEMVVIPAGKFRMGAIFGGGDPDEKP
VHWVSIARPFAMGKYEVTFGEYDRFCDATGREKPKDGRRWFGPLSRDWGRGRMPAMNVSWEDAVAYAKWLSEQTGQKYRL
PSEAEWEFAARGGKDTPFWWGGTAGEKRANCKGCGSKWDNKKGAPAGSFAANPYGLFDTAGNVWEWCLDTWHDSYTGAPT
DGSPWLGGDDTRRVQRGGSFGSKVRYIRSSARGRGAPDGQYVYLGFRVLREL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=265, Percent_Identity=35.4716981132075, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38202250, Length=290, Percent_Identity=33.1034482758621, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI257470977, Length=285, Percent_Identity=30.8771929824561, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI194248087, Length=277, Percent_Identity=31.4079422382672, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI194248088, Length=292, Percent_Identity=29.1095890410959, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226437577, Length=172, Percent_Identity=36.046511627907, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130397, Length=173, Percent_Identity=34.1040462427746, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31971; Mature: 31971

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTHRLATGAALLAFLVIVSPLAAEVKPAAKVSSPPPAAGSVFRDRLKNGSSGPEMVVI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEE
PAGKFRMGAIFGGGDPDEKPVHWVSIARPFAMGKYEVTFGEYDRFCDATGREKPKDGRRW
CCCCEEEEEEECCCCCCCCCEEEEEHHCHHHCCEEEEECCCHHHHHCCCCCCCCCCCHHH
FGPLSRDWGRGRMPAMNVSWEDAVAYAKWLSEQTGQKYRLPSEAEWEFAARGGKDTPFWW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHCCCCCCCEEE
GGTAGEKRANCKGCGSKWDNKKGAPAGSFAANPYGLFDTAGNVWEWCLDTWHDSYTGAPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
DGSPWLGGDDTRRVQRGGSFGSKVRYIRSSARGRGAPDGQYVYLGFRVLREL
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHC
>Mature Secondary Structure
MMNTHRLATGAALLAFLVIVSPLAAEVKPAAKVSSPPPAAGSVFRDRLKNGSSGPEMVVI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEE
PAGKFRMGAIFGGGDPDEKPVHWVSIARPFAMGKYEVTFGEYDRFCDATGREKPKDGRRW
CCCCEEEEEEECCCCCCCCCEEEEEHHCHHHCCEEEEECCCHHHHHCCCCCCCCCCCHHH
FGPLSRDWGRGRMPAMNVSWEDAVAYAKWLSEQTGQKYRLPSEAEWEFAARGGKDTPFWW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHCCCCCCCEEE
GGTAGEKRANCKGCGSKWDNKKGAPAGSFAANPYGLFDTAGNVWEWCLDTWHDSYTGAPT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
DGSPWLGGDDTRRVQRGGSFGSKVRYIRSSARGRGAPDGQYVYLGFRVLREL
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]