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The map label for this gene is uvrA [H]

Identifier: 78223779

GI number: 78223779

Start: 2933596

End: 2933850

Strand: Reverse

Name: uvrA [H]

Synonym: Gmet_2582

Alternate gene names: 78223779

Gene position: 2933850-2933596 (Counterclockwise)

Preceding gene: 78223780

Following gene: 78223778

Centisome position: 73.39

GC content: 63.53

Gene sequence:

>255_bases
GTGAGGAGAAGCCCCGCGACGTTTTGCGGGGCTTCTGTTTGGGATCACGGGAATCTCGATCTCGACCTTCCCCTTGGTGA
ACTGATCGTCGTCACCGGTGTCTCCGGCTCGGGGAAGTCGTCCCTGGCCTTCGACACGGTCTATGCCGAGGGGCAGCGCC
GCTACGTGGAGACCTTCTCTCCCTACGCCCGCCAGTTCCTGGAGCGGATGGCCTGTCCGCACCCCAGTTCAGTTCCCTCA
GTGCCGTGCTCCTGA

Upstream 100 bases:

>100_bases
CCATATCCTCGATCATGAGGAGCACGACATGATGAGGCCGCTGGTGGTCATCTAGAATGAGCCTCCAGGCGACGACAGCA
ACCCGGTGCGTTAGCGCCGG

Downstream 100 bases:

>100_bases
AGTTGCACAATTTCAACCCTCATCTAGAATTGGAGAAAGCCTTTCTAGCTCGACCGGGGTTAGTGTCGCACTTGTCTGGG
TGAATCTCCGTGGGCGTTGA

Product: excinuclease ATPase subunit-like

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MRRSPATFCGASVWDHGNLDLDLPLGELIVVTGVSGSGKSSLAFDTVYAEGQRRYVETFSPYARQFLERMACPHPSSVPS
VPCS

Sequences:

>Translated_84_residues
MRRSPATFCGASVWDHGNLDLDLPLGELIVVTGVSGSGKSSLAFDTVYAEGQRRYVETFSPYARQFLERMACPHPSSVPS
VPCS
>Mature_84_residues
MRRSPATFCGASVWDHGNLDLDLPLGELIVVTGVSGSGKSSLAFDTVYAEGQRRYVETFSPYARQFLERMACPHPSSVPS
VPCS

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=64, Percent_Identity=65.625, Blast_Score=86, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 9107; Mature: 9107

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSPATFCGASVWDHGNLDLDLPLGELIVVTGVSGSGKSSLAFDTVYAEGQRRYVETFS
CCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHCC
PYARQFLERMACPHPSSVPSVPCS
HHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRSPATFCGASVWDHGNLDLDLPLGELIVVTGVSGSGKSSLAFDTVYAEGQRRYVETFS
CCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEHHHHCCCCHHHHHHCC
PYARQFLERMACPHPSSVPSVPCS
HHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]